Mitochondrial Ribosomal Protein S15 Proteins (MRPS15)

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S15P family. The encoded protein is more than two times the size of its E. coli counterpart, with the 12S rRNA binding sites conserved. Between human and mouse, the encoded protein is the least conserved among small subunit ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 15q and 19q.

• CG4207 gene product from transcript CG4207-RA (bonsai)
• mitochondrial ribosomal protein S15 (mrps15)
• mitochondrial ribosomal protein S15 (MRPS15)
• mitochondrial ribosomal protein S15 (mrpS15)
• mitochondrial ribosomal protein S15 L homeolog (mrps15.L)
• Show all gene names
• mitochondrial ribosomal protein S15 (Mrps15)

• 1500003E24Rik protein
• 2410002B11Rik protein
• CG4207 protein
• Dmel\\CG4207 protein
• DmMRPS15 protein
• Show all synonym aliases
• MPR-S15 protein
• Mprs15 protein
• MRP-S15 protein
• mRpS15 protein
• RPMS15 protein
• S15mt protein
• zgc:92862 protein

CG4207-PA , bonsai-PA , 28S ribosomal protein S15, mitochondrial , S15mt , MRP-S15 , mitochondrial ribosomal protein S15