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The protein encoded by MTRF1 was determined by in silico methods to be a mitochondrial protein with similarity to the peptide chain release factors (RFs) discovered in bacteria and yeast. Additionally we are shipping MTRF1 Antibodies (31) and MTRF1 Proteins (2) and many more products for this protein.
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Purified mtRF1 did not induce translation termination in vitro nor did mtRF1 restore mitochondrial translation machinery in mutated S. cerevisiae in vivo. A different mtRF, mtRF1a, was found.
The protein encoded by this gene was determined by in silico methods to be a mitochondrial protein with similarity to the peptide chain release factors (RFs) discovered in bacteria and yeast. The peptide chain release factors direct the termination of translation in response to the peptide chain termination codons. Initially thought to have a role in the termination of mitochondria protein synthesis, a recent publication found no mitochondrial translation release functionality. Multiple alternatively spliced transcript variants have been suggested by mRNA and EST data\; however, their full-length natures are not clear.
mitochondrial translational release factor 1
, mitochondrial translational release factor 1-like
, peptide chain release factor 1, mitochondrial-like
, mitochontrial peptide chain release factor 1
, peptide chain release factor 1, mitochondrial