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ZAK is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). Additionally we are shipping ZAK Antibodies (70) and ZAK Proteins (9) and many more products for this protein.
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This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
mitogen-activated protein kinase kinase kinase MLT
, MLK-like mitogen-activated protein triple kinase
, human cervical cancer suppressor gene 4 protein
, mixed lineage kinase 7
, mixed lineage kinase with a leucine zipper and a sterile alpha motif
, mixed lineage kinase-related kinase MRK-beta
, MLK-related kinase
, leucine zipper- and sterile alpha motif kinase ZAK
, mixed lineage kinase-related kinase
, sterile alpha motif- and leucine zipper-containing kinase AZK
, sterile-alpha motif and leucine zipper containing kinase AZK