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Induces rhoa activation and activates nppa transcription and myofibrillar organization through the rho/rock signaling pathway (By similarity). Additionally we are shipping MURC Antibodies (23) and MURC Proteins (7) and many more products for this protein.
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murcb mutant zebrafish, display impaired swimming capacity, skeletal muscle fibrosis and T-tubule abnormalities during development.
MURC/cavin-4, especially in combination with Cav-3 (show CAV3 ELISA Kits), may play a consistent role in the differentiation process of rhabdomyosarcoma.
MURC mutations impart loss-of-function effects on MURC functions and probably are causal variants in human dilated cardiomyopathy
MURC modulates RhoA (show RHOA ELISA Kits) signaling, and MURC plays an important role in the development of cardiac dysfunction and conduction disturbance with increased vulnerability to atrial arrhythmias.
The MURC/Cavin-4 in vascular smooth muscle cells modulates abdominal aortic aneurysm (AAA (show AAAS ELISA Kits)) progression at the early stage via the activation of JNK (show MAPK8 ELISA Kits) and MMP-9 (show MMP9 ELISA Kits). MURC/Cavin-4 is a potential therapeutic target against AAA (show AAAS ELISA Kits) progression.
MURC/Cavin-4 facilitates recruitment of ERK (show EPHB2 ELISA Kits) to caveolae and concentric cardiac hypertrophy induced by alpha1-adrenergic receptors.
findings suggest that MURC is involved in the skeletal myogenesis that results from modulation of myogenin (show MYOG ELISA Kits) expression and ERK (show EPHB2 ELISA Kits) activation; MURC may play pivotal roles in the molecular mechanisms of skeletal myogenic differentiation
Data show that MURC/Cavin-4 forms a multiprotein complex that associates with caveolae, and identify Cavin-4 as a novel muscle disease candidate caveolar protein.
Induces rhoa activation and activates nppa transcription and myofibrillar organization through the rho/rock signaling pathway (By similarity).
muscle-related coiled-coil protein
, muscle-restricted coiled-coil protein
, PTRF/SDPR family protein