Myb-Binding Protein 1A (MYBBP1A) ELISA Kits

Mouse (Murine) Myb-Binding Protein 1A (MYBBP1A) interaction partners

1. Mybbp1a is a novel negative regulator of Sirt7.

2. Data show that down-regulation of MYBBP1A decreases the growth rate of wild type mouse embryonic stem cells, embryo fibroblasts (MEFs) and of human HeLa cells, where it also promotes apoptosis.

3. Mybbp1a may play a dual role in the rRNA metabolism, potentially linking and coordinating ribosomal DNA transcription and pre-rRNA processing to allow for the efficient synthesis of ribosomes.

4. Myb-binding protein 1a was identified as a novel negative regulator of muscle-specific gene expression and myoblast differentiation.

5. Myb-binding protein p160 is a novel target of the von Hippel-Lindau tumor suppressor.

6. Ipr1 might be involved in apoptosis pathway via MYBBP1A.

7. Myb-binding protein 1a augments AhR-dependent gene expression

8. Mybbp1a is a nucleocytoplasmic shuttling protein involved in nuclear import and export via CRM1-dependent and -independent pathways.

9. These data show that p160 is a novel regulator of Prep1-Pbx1 transcriptional activity.

10. SRC-3 alone of the p160 coactivators enhanced CAR transactivation in hepatic cells without PB treatment.

11. Mybbp1a may connect the ribosome biogenesis and the Myb-dependent transcription, which controls cell cycle progression and proliferation.

12. Results suggest that Prep1 controls insulin sensitivity through the p160-GLUT4 pathway.

Human Myb-Binding Protein 1A (MYBBP1A) interaction partners

1. The results indicated that both the heterozygous genotype GC and homozygous genotype CC in rs3809849 in MYBBP1A had significant effects on the risk of pulmonary tuberculosis, and heterozygous genotype CT in rs9061 in SP110 also had similar effects.

2. We propose that the nucleolus functions as a stress sensor to modulate p53 protein levels and its acetylation status, determining cell fate between cell cycle arrest and apoptosis by regulating MYBBP1A translocation.

3. MYBBP1A(low)AKT(Ser473)(high) staining pattern serves not only as a marker for the pre-senescent stage but also as an indicator of OPSCC patients at high risk for treatment failure.

4. TPPII, MYBBP1A and CDK2 form a protein-protein interaction network.

5. MYBBP1A functions to enhance p53 tetramerization that is necessary for p53 activation.

6. Mybbp1a is a novel negative regulator of Sirt7.

7. Regulators, including BCL11A, MYB, and KLF1, hold great promise to develop targeted and more effective approaches for HbF induction.

8. MYBBP1A-p53 binding property can account for efficient p53-activation by MYBBP1A under nucleolar stress. Our results support the idea that MYBBP1A plays catalytic roles in p53 acetylation and activation

9. Suggest that MYBBP1A is required for p53 activation during anoikis; therefore, it is involved in suppressing colony formation and the tumorigenesis of breast cancer cells.

10. Data show that down-regulation of MYBBP1A decreases the growth rate of wild type mouse embryonic stem cells, embryo fibroblasts (MEFs) and of human HeLa cells, where it also promotes apoptosis.

11. Study suggests that a combination of SP110 and MYBBP1A gene polymorphisms may serve as a novel marker for identifying the risk of developing TB in the Chinese Han population.

12. Results from our present work reveal a previously unrecognized co-repressor role of Mybbp1a in rRNA expression.

13. Mybbp1a may play a dual role in the rRNA metabolism, potentially linking and coordinating ribosomal DNA transcription and pre-rRNA processing to allow for the efficient synthesis of ribosomes.

14. We provide experimental evidence that MYBBP1A is an important molecular switch in the regulation of tumor cell proliferation versus migration in head and neck squamous cell carcinoma cells.

15. When rRNA transcription was suppressed by nucleolar stress, MYBBP1A translocated to the nucleoplasm and facilitated p53-p300 interaction to enhance p53 acetylation.

16. identified MYBBP1A as a novel Aurora B substrate and serine 1303 as the major phosphorylation site

17. Myb-binding protein 1a was identified in anti-SMN pulldowns as interacting with SMN proteins.

18. These results indicate that MYBBP1a is a novel NF-kappaB co-repressor of transcription that competes with p300 and may function to regulate cell type specific genes.

19. Expression of Ets-2, SRC-1 and c-Myc individually are all associated with reduced disease-free survival in breast cancer

20. SRC-1 is a strong independent predictor of reduced disease free survival, whereas the interactions of the p160 proteins with estrogen receptor alpha can predict the response of patients to endocrine treatment.