anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila) Antibodies

MLL encodes a transcriptional coactivator that plays an essential role in regulating gene expression during early development and hematopoiesis.

Data Quality
  • 6
  • 11
Type
  • 48
    Primary
Target
  • 48
Reactivity
  • 48
  • 15
  • 10
Application
  • 25
  • 25
  • 23
  • 9
  • 5
Host
  • 41
  • 7
Clonality
  • 42
  • 6
Clone
  • 4
  • 1
Binding Specificity
  • 10
  • 7
  • 7
  • 4
  • 3
Conjugate
  • 29
  • 3
  • 2
  • 2
  • 2
Isotype
  • 23
  • 6
  • 3
Format
  • 31
  • 1
Suggested next Filters
48 Products
ReactivityHuman
Application IHC, ELISA, WB
Order details Cat. No. ABIN969286
$393.80
100 μL
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityHuman, Mouse
Application ChIP-seq, ChIP, ICC, IF, WB
Order details Cat. No. ABIN2668494
$530.83
100 μg
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 1 to 2 Business Days
ReactivityHuman
Application IHC
Order details Cat. No. ABIN966301
Pubmed
$559.35
0.1 mg
Plus shipping costs $45.00
Delivery in 4 to 6 Business Days
$559.35
0.1 mg
Plus shipping costs $45.00
Delivery in 4 to 6 Business Days
ReactivityHuman
Application ELISA, IHC (p), WB
Order details Cat. No. ABIN5583588
$374.67
100 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application IHC (p)
Order details Cat. No. ABIN543317
$431.43
400 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application EIA, IHC (p), WB
Order details Cat. No. ABIN1108254
$462.00
0.1 mL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman
Application EIA, IHC (p), WB
Order details Cat. No. ABIN356674
$522.50
0.4 mL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman
Application FACS, IHC (p)
Order details Cat. No. ABIN5536269
$550.00
400 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application FACS, IHC
Order details Cat. No. ABIN2996098
$590.93
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman, Mouse, Rat
Application ELISA, IHC (p)
Order details Cat. No. ABIN4901952
$369.83
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN2140641
$382.86
100 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman
Application ELISA, IHC (p), WB
Order details Cat. No. ABIN4901951
$540.68
100 μL
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN561828
$238.67
50 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman, Mouse, Rat
Application IF, WB
Order details Cat. No. ABIN6715146
$390.55
100 μL
Plus shipping costs $45.00
Delivery in 6 to 11 Business Days
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Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila) (MLL) Antigen Profile

Protein Summary

This gene encodes a transcriptional coactivator that plays an essential role in regulating gene expression during early development and hematopoiesis. The encoded protein contains multiple conserved functional domains. One of these domains, the SET domain, is responsible for its histone H3 lysine 4 (H3K4) methyltransferase activity which mediates chromatin modifications associated with epigenetic transcriptional activation. This protein is processed by the enzyme Taspase 1 into two fragments, MLL-C and MLL-N. These fragments reassociate and further assemble into different multiprotein complexes that regulate the transcription of specific target genes, including many of the HOX genes. Multiple chromosomal translocations involving this gene are the cause of certain acute lymphoid leukemias and acute myeloid leukemias. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with MLL

  • lysine methyltransferase 2A (KMT2A) antibody
  • lysine (K)-specific methyltransferase 2A (Kmt2a) antibody
  • lysine methyltransferase 2A (Kmt2a) antibody
  • 6430520K01 antibody
  • ALL-1 antibody
  • All1 antibody
  • Cxxc7 antibody
  • HRX antibody
  • HTRX1 antibody
  • mKIAA4050 antibody
  • Mll antibody
  • MLL/GAS7 antibody
  • Mll1 antibody
  • MLL1A antibody
  • TET1-MLL antibody
  • TRX1 antibody
  • WDSTS antibody

Protein level used designations for MLL

CDK6/MLL fusion protein , CXXC-type zinc finger protein 7 , MLL-AF4 der(11) fusion protein , MLL/GAS7 fusion protein , MLL/GMPS fusion protein , histone-lysine N-methyltransferase 2A , lysine N-methyltransferase 2A , myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) , myeloid/lymphoid or mixed-lineage leukemia protein 1 , trithorax-like protein , zinc finger protein HRX , histone-lysine N-methyltransferase MLL , myeloid/lymphoid or mixed-lineage leukemia 1 , trithorax Drosophila , Mixed-lineage leukemia (also acute lymphocytic leukemia 1 or tritorax Drosophila gene)

GENE ID SPECIES
4297 Homo sapiens
214162 Mus musculus
315606 Rattus norvegicus