anti-Myomesin 1 (MYOM1) Antibodies

The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MYOM1 8736 P52179
MYOM1 17929 Q62234
MYOM1 316740  
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Top anti-Myomesin 1 Antibodies at antibodies-online.com

Showing 10 out of 56 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB Host: RabbitTarget Name: MYOM1Antibody Dilution: 1.0ug/mlSample Tissue: NCI-H226 cell lysate 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human skeletal muscle, using MYOM1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p) 100 μL 11 to 14 Days
$493.17
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis in HL-60 cell line lysates (35ug/lane). MYOM1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated ELISA, IHC   100 μL Available
$363.46
Details
Human Rabbit Un-conjugated WB   100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, IHC (p) Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue using MYOM1 polyclonal antibody . Peptide 100 μg 11 to 12 Days
$374.67
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged MYOM1 is 0.03 ng/ml as a capture antibody. Western Blot detection against Immunogen (36.63 KDa) . 100 μg 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cardiac muscle with MYOM1 polyclonal antibody  shows moderate cytoplasmic positivity in myocytes at 1:2500-1:5000 dilution. 100 μL 11 to 12 Days
$577.33
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   200 μL 11 to 16 Days
$658.43
Details

More Antibodies against Myomesin 1 Interaction Partners

Human Myomesin 1 (MYOM1) interaction partners

  1. Crystal structure of the obscurin(-like-1):myomesin complex reveals a trans-complementation mechanism whereby an incomplete immunoglobulin-like domain assimilates an isoform-specific myomesin interdomain sequence.

  2. individual subfragments of titin and myomesin composed of Fn type III and Ig-like domains can activate expression of two IGF-1 splice forms in cultured myoblasts

  3. myomesin could act as a highly elastic ribbon to maintain the overall structural organization of the sarcomeric M-band.

  4. Our results suggest that the downregulation of MBNL proteins should lead to the abnormal splicing of MYOM1 exon 17a in DM1 muscle.

  5. EH-myomesin levels were up-regulated at least 10 times in dilated cardiomyopathy patients compared to controls.

  6. This missense mutation caused significant changes of biochemical and biophysical properties of myomesin fragments indicating a role in the pathogenesis of hypertrophic cardiomyopathy .

  7. Results identify muscle-type creatine kinase as a binding partner of a central portion of myomesin and the closely related M-protein.

  8. visco-elastic properties of myomesin might be crucial for the stability of the sarcomere

Mouse (Murine) Myomesin 1 (MYOM1) interaction partners

  1. Skelemin association with alphaIIbbeta3 integrin: a structural model.

  2. ectopically expressed Myomesin-I was primarily targeted to the nucleus; presence of Myomesin-I in the nucleus led to the differential expression of more than 42 genes

Myomesin 1 (MYOM1) Antigen Profile

Protein Summary

The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II, in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50% sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure of the sarcomere arises from muscle-specific members of the superfamily of immunoglobulin-like proteins. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with anti-Myomesin 1 (MYOM1) Antibodies

  • myomesin 1 (MYOM1) antibody
  • myomesin 1 (Myom1) antibody
  • myomesin 1, 185kDa (MYOM1) antibody
  • D430047A17Rik antibody
  • SKELEMIN antibody

Protein level used designations for anti-Myomesin 1 (MYOM1) Antibodies

190 kDa connectin-associated protein , 190 kDa titin-associated protein , EH-myomesin , myomesin (M-protein) 1 (190kD) , myomesin 1 (skelemin) 185kDa , myomesin 1, 185kDa , myomesin family member 1 , myomesin-1 , skelemin

GENE ID SPECIES
8736 Homo sapiens
17929 Mus musculus
316740 Rattus norvegicus
538404 Bos taurus
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