MYOT encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction.
Myotilin (MYOT) Protein Profile
This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Gene names and symbols associated with Myotilin Proteins (MYOT)
myotilin (MYOT) antibody
myotilin (Myot) antibody
myotilin (myot) antibody
Protein level used designations for Myotilin Proteins (MYOT)
57 kDa cytoskeletal protein
, myofibrillar titin-like Ig domains protein
, titin immunoglobulin domain protein (myotilin)
, titan-like protein
, titin immunoglobulin domain protein
, LOW QUALITY PROTEIN: myotilin