anti-Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) Antibodies

The protein encoded by MARCKS is a substrate for protein kinase C. Additionally we are shipping MARCKS Kits (20) and MARCKS Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MARCKS 17118 P26645
MARCKS 25603  
MARCKS 4082 P29966
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Top anti-MARCKS Antibodies at antibodies-online.com

Showing 10 out of 245 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>Sample:</b> SH-SY5Y cells 2.0x10<sup>5</sup> cells<b><br></b><b>Primary dilution:</b> 1:2500<br><b>Secondary Antibody</b>: HRP-conjugated goat anti-rabbit IgG<br><b>Secondary dilution:</b> 1:5000<br><b>Image Submitted by</b>:Atsuhiro Tanabe<br>Pharma Sci Kitasato University 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-MARCKS AntibodyTitration: 1.0 µg/mL <br /> Positive Control: Fetal Liver 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Chicken Rabbit Un-conjugated IP, WB Western blot analysis of MARCKS expression in HeLa (A), RAW264.7 (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Chicken Rabbit Un-conjugated WB Western blot analysis of MARCKS (pS163) expression in MCF7 PMA-treated (A), SP2/0 PMA-treated (B), PC12 PMA-treated (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$575.00
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from Jurkat cells, using MARCKS (Ab-158) Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of A549 cells, using MARCKS (Ab-158) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of hMARCKS-K254 (ABIN389097) in Hela cell line lysates (35 µg/lane). MARCKS (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from K562 cells treated with EGF 200ng/ml 30', using MARCKS (Phospho-Ser158) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated WB MARCKS monoclonal antibody (M04), clone 2H4. Western Blot analysis of MARCKS expression in Raw 264.7. Detection limit for recombinant GST tagged MARCKS is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to MARCKS on HeLa cell (antibody concentration 10 µg/mL). MARCKS monoclonal antibody (M06), clone 2C2. Western Blot analysis of MARCKS expression in Raw 264.7. (OMIN,80 kDa,http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=177061 50 μg Log in to see 8 to 11 Days
$450.00
Details

MARCKS Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-MARCKS Antibodies

  1. Chinese Hamster Polyclonal MARCKS Primary Antibody for WB - ABIN152966 : Zhang, Ahmed, McFarlane, Capone, Boreham, Truant, Igdoura, Trigatti: Regulation of SR-BI-mediated selective lipid uptake in Chinese hamster ovary-derived cells by protein kinase signaling pathways. in Journal of lipid research 2007 (PubMed)
    Show all 2 Pubmed References

  2. Human MARCKS Primary Antibody for IHC - ABIN966535 : Pariser, Herradon, Ezquerra, Perez-Pinera, Deuel: Pleiotrophin regulates serine phosphorylation and the cellular distribution of beta-adducin through activation of protein kinase C. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)

  3. Human Polyclonal MARCKS Primary Antibody for IF, WB - ABIN362996 : Litherland, Elias, Hui, Macdonald, Catterall, Barter, Farren, Jefferson, Rowan: Protein kinase C isoforms zeta and iota mediate collagenase expression and cartilage destruction via STAT3- and ERK-dependent c-fos induction. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 Pubmed References

More Antibodies against MARCKS Interaction Partners

Xenopus laevis Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) interaction partners

  1. The results indicated MARCKS may be the missing link in the regulation of the function (i.e., sodium transport) of epithelial sodium channels by anionic phospholipids.

Mouse (Murine) Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) interaction partners

  1. ENaC (show SCNN1A Antibodies) activity is regulated by calpain-2 (show CAPN2 Antibodies) proteolysis of MARCKS.

  2. In the absence of Pin1 (show PIN1 Antibodies), MARCKS is hyper-phosphorylated, leading to loss of cell adhesions, and collapse of the growth cone.

  3. Findings suggest that MIR429 modulates mucin (show SLC13A2 Antibodies) secretion in human colorectal cells and mouse colitis tissues by up-regulating of MARCKS expression.

  4. Conditional deletion of MARCKS in ECs induces intracellular accumulation of mucins, elevated oxidative stress, and lipid droplet buildup.

  5. MARCKS acts as a "molecular switch," binding to and regulating PIP2 signaling to regulate processes like proplatelet extension (microtubule-driven) vs proplatelet branching (Arp2/3 and actin polymerization-driven).

  6. MARCKS knockdown arrested VSMC cell cycle by decreasing KIS (show UHMK1 Antibodies) expression. Decreased KIS (show UHMK1 Antibodies) expression resulted in nuclear trapping of p27kip1 (show CDKN1B Antibodies) in VSMCs.

  7. MARCKS regulates the expression of proinflammatory cytokines in macrophages through activation of p38 (show CRK Antibodies)/JNK (show MAPK8 Antibodies) MAPK (show MAPK1 Antibodies) and NF-kappaB (show NFKB1 Antibodies).

  8. Targeting phospho-MARCKS overcomes drug-resistance and induces antitumor activity in preclinical models of multiple myeloma.

  9. Grin 1 (show GPRIN1 Antibodies) is identified as a novel Cdk5 (show CDK5 Antibodies) substrate and MARCKS is confirmed as a Cdk5 (show CDK5 Antibodies) substrate.

  10. MARCKS appears to be a nonessential regulatory protein in mast cell exocytosis but exerts a negative modulation.

Zebrafish Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) interaction partners

  1. Marcksb is required for proper gastrulation movements of zebrafish.

Human Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) interaction partners

  1. we propose a role for MARCKS in a novel mechanism of BTZ (show CASC3 Antibodies) resistance via exocytosis of ubiquitinated proteins in BTZ (show CASC3 Antibodies)-resistant cells leading to quenching of proteolytic stress.

  2. MARCKS overexpression might in part explain the poor prognosis of inflammatory breast cancer.

  3. Authors determined that myristoylated alanine-rich C-kinase substrate (MARCKS) was highly expressed in ovarian stroma, and was required for the differentiation and tumor promoting function of CAFs (show TBX1 Antibodies).

  4. Data indicate MARCKS (myristoylated alanine-rich C-kinase substrate) as a target of miR (show MLXIP Antibodies)-21.

  5. data suggest a major contribution of MARCKS to kidney cancer growth and provide an alternative therapeutic strategy of improving the efficacy of multikinase inhibitors.

  6. These data suggested that miR34c3p acts as a tumor suppressor via regulation of MARCKS expression in OS progression

  7. Ca(2+)-PKC-MARCKS-PIP2-PI3K-PIP3 system functions as an activation module in vitro

  8. Findings show that calmodulin (CaM) stimulates phosphoinositide-3-kinase (PI3K) lipid kinase activity by binding MARCKS and displacing it from phosphatidylinositol 4,5-bisphosphate (PIP2) headgroups, thereby releasing free PIP2 that recruits active PI3K to the membrane and serves as the substrate for the generation of phosphatidylinositol 3,4,5-trisphosphate (PIP3).

  9. Findings suggest that MIR429 modulates mucin (show SLC13A2 Antibodies) secretion in human colorectal cells and mouse colitis tissues by up-regulating of MARCKS expression.

  10. Knockdown of MARCKS in HepG2 cells reduced cell migration and invasion, but not cell proliferation.

Cow (Bovine) Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) interaction partners

  1. MARCKS protein mediates hydrogen peroxide regulation of endothelial permeability.

  2. a critical role for H(2)O(2) in angiotensin-II signaling to the endothelial cytoskeleton in a novel pathway that is critically dependent on MARCKS, Rac1, and c-Abl.

  3. These findings demonstrate a critical role for MARCKS-phosphatidylinositol-4,5-diphosphate signaling in regulating dendrite development.

  4. Protein kinase C (show PKC Antibodies) mediated inhibition of endothelial L-arginine (show GATM Antibodies) transport is mediated by MARCKS protein

MARCKS Antigen Profile

Protein Summary

The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

Gene names and symbols associated with MARCKS

  • myristoylated alanine-rich protein kinase C substrate (marcks) antibody
  • myristoylated alanine rich protein kinase C substrate (MARCKS) antibody
  • methyl binding domain106 (mbd106) antibody
  • myristoylated alanine-rich protein kinase C substrate S homeolog (marcks.S) antibody
  • myristoylated alanine rich protein kinase C substrate (Marcks) antibody
  • myristoylated alanine-rich protein kinase C substrate b (marcksb) antibody
  • 80K-L antibody
  • KINC antibody
  • MACS antibody
  • MARCKS antibody
  • MGC89127 antibody
  • PKCSL antibody
  • PRKCSL antibody
  • wu:fb55c06 antibody
  • wu:fb92d04 antibody
  • wu:fc19b04 antibody
  • wu:fc44a10 antibody
  • zgc:110235 antibody

Protein level used designations for MARCKS

myristoylated alanine-rich protein kinase C substrate , methyl binding domain , Zmmbd2 , PCO124731 , PCO124731_ov , myristoylated alanine-rich C-kinase substrate , Myristoylated alanine-rich protein kinase C substrate , protein kinase C substrate 80 kDa protein , myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L) , phosphomyristin , protein kinase C substrate, 80 kDa protein, light chain , myristoylated alanine-rich C kinase substrate (MARCKS) , ACAMP-81

GENE ID SPECIES
448317 Xenopus (Silurana) tropicalis
694077 Macaca mulatta
742020 Pan troglodytes
100345174 Oryctolagus cuniculus
542069 Zea mays
379767 Xenopus laevis
17118 Mus musculus
25603 Rattus norvegicus
323201 Danio rerio
4082 Homo sapiens
396473 Gallus gallus
613548 Bos taurus
612436 Canis lupus familiaris
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