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Catalytic subunit of the N-terminal acetyltransferase C (NatC) complex. Additionally we are shipping NAA30 Antibodies (22) and many more products for this protein.
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ARFRP1 (show ARFRP1 Proteins) shifted from a predominantly cis (show CISH Proteins)-Golgi and endosome-to-trans-Golgi network localization to localizing both Golgi and non-Golgi vesicular structures in hNaa30-depleted cells.
Overexpression of full-length Naa30 increased cell viability.
Data show that the human NatC complex Nt-acetylates a broad range of cellular proteins, and that depletion of the catalytic subunit Naa30 affects mitochondrial morphology and function.
NAT12/NAA30 plays an important role in growth and survival of GICs possibly by regulating hypoxia response (HIF1a (show HIF1A Proteins)), levels of p-MTOR (show FRAP1 Proteins) (Ser2448) and the p53 (show TP53 Proteins) pathway.
Human Naa30 (MAK3) is the catalytic subunit of the human NatC N-terminal acetyltransferase (show NAA15 Proteins) complex. NatC acetylates hydrophobic Met-starting N-termini, and NatC knockdown induces p53 (show TP53 Proteins)-dependent apoptosis.
Catalytic subunit of the N-terminal acetyltransferase C (NatC) complex. Catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Leu-Ala and Met-Leu-Gly. Necessary for the lysosomal localization and function of ARL8B.
N-acetyltransferase 12 (GCN5-related, putative)
, N-acetyltransferase MAK3 homolog
, N-alpha-acetyltransferase 30
, N-alpha-acetyltransferase 30, NatC catalytic subunit
, natC catalytic subunit
, putative N-acetyltransferase
, N-acetyltransferase 12
, Nalpha acetyltransferase 30