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May have histone acetyltransferase (Potential). Additionally we are shipping NAT10 Proteins (4) and and many more products for this protein.
Showing 10 out of 64 products:
Human Polyclonal NAT10 Primary Antibody for IHC (p), IHC - ABIN451608
Yin, Ma, Selliah, Shivers, Cron, Finkel: Effective gene suppression using small interfering RNA in hard-to-transfect human T cells. in Journal of immunological methods 2006
immunohistochemistry staining of NAT10 in hepatocellular carcinoma tissues demonstrates that the cytoplasmic NAT10 is correlated with poorer prognosis compared with nuclear NAT10, while the membranous NAT10 predicts the poorest clinical outcome of the patients.
Increased NAT10 expression levels are associated with shortened hepatocellular carcinoma (HCC (show FAM126A Antibodies)) patient survival and correlated with mutant p53 (show TP53 Antibodies) levels. NAT10 upregulates mutant p53 (show TP53 Antibodies) level and might enhance its tumorigenic activity. Hence, it is proposed that NAT10 could be a potential prognostic and therapeutic candidate for p53 (show TP53 Antibodies)-mutated HCC (show FAM126A Antibodies).
NAT10 is acetylated in vivo and autoacetylated in vitro
NAT10 translocates to nucleoplasm to bind and acetylate p53 (show TP53 Antibodies) at K120 upon cellular stress.
The subcellular redistribution of NAT10 can be induced by decreases in GSK-3b activity. This redistribution increases cancer cell motility, and is, thus, correlated with invasive potential and poorer clinical outcome
Identification of NAT10 as responsible for both 18S rRNA and leucine/serine tRNA acetylation.
NAT10 is an ATP-dependent RNA acetyltransferase responsible for formation of N(4)-acetylcytidine (ac(4 (show ADCY4 Antibodies))C) at position 1842 in the terminal helix of mammalian 18 S rRNA.
we identified hALP, a histone acetyl-transferase (show HAT1 Antibodies) as a novel t-UTP
hALP is a nucleolar protein (show MCRS1 Antibodies), and the nucleolar localization is mediated by its carboxy terminal domain.
The above results suggested that NAT10 could be involved in DNA damage response and increased cellular resistance to genotoxicity.
May have histone acetyltransferase (Potential).
, N-acetyltransferase-like protein
, novel putative ATPase domain containing protein
, N-acetyltransferase 10 (GCN5-related)
, N-acetyltransferase Nat10 (predicted)
, N-acetyltransferase 10-like
, n-acetyltransferase 10-like