N-Acetyltransferase 10 (GCN5-Related) Proteins (NAT10)

May have histone acetyltransferase (Potential). Additionally we are shipping NAT10 Antibodies (67) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NAT10 55226 Q9H0A0
NAT10 98956 Q8K224
Rat NAT10 NAT10 311257  
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Top NAT10 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,376.85
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,376.85
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$888.80
Details
Wheat germ Human GST tag 2 μg 11 to 12 Days
$297.14
Details

NAT10 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for N-Acetyltransferase 10 (GCN5-Related) (NAT10) Interaction Partners

Human N-Acetyltransferase 10 (GCN5-Related) (NAT10) interaction partners

  1. High NAT10 expression is associated with Hutchinson-Gilford progeria syndrome by sequestering TNPO1 in the cytoplasm.

  2. we demonstrate that the acetylation status of NAT10 is important for the anabolism-catabolism transition in response to energy stress, providing a novel mechanism by which nucleolar proteins control rRNA synthesis and autophagy in response to the cellular energy supply.

  3. immunohistochemistry staining of NAT10 in hepatocellular carcinoma tissues demonstrates that the cytoplasmic NAT10 is correlated with poorer prognosis compared with nuclear NAT10, while the membranous NAT10 predicts the poorest clinical outcome of the patients.

  4. Increased NAT10 expression levels are associated with shortened hepatocellular carcinoma (HCC) patient survival and correlated with mutant p53 levels. NAT10 upregulates mutant p53 level and might enhance its tumorigenic activity. Hence, it is proposed that NAT10 could be a potential prognostic and therapeutic candidate for p53-mutated HCC.

  5. NAT10 is acetylated in vivo and autoacetylated in vitro

  6. NAT10 translocates to nucleoplasm to bind and acetylate p53 at K120 upon cellular stress.

  7. The subcellular redistribution of NAT10 can be induced by decreases in GSK-3b activity. This redistribution increases cancer cell motility, and is, thus, correlated with invasive potential and poorer clinical outcome

  8. Identification of NAT10 as responsible for both 18S rRNA and leucine/serine tRNA acetylation.

  9. NAT10 is an ATP-dependent RNA acetyltransferase responsible for formation of N(4)-acetylcytidine (ac(4)C) at position 1842 in the terminal helix of mammalian 18 S rRNA.

  10. we identified hALP, a histone acetyl-transferase as a novel t-UTP

  11. hALP is a nucleolar protein, and the nucleolar localization is mediated by its carboxy terminal domain.

  12. The investigation suggested that hALP influences the activity of histone acetylation and could up-regulate telomerase activity through transactivation of hTERT promoter.

  13. The above results suggested that NAT10 could be involved in DNA damage response and increased cellular resistance to genotoxicity.

  14. chromosome de-condensation needs the function of an inner nuclear membrane (INM) protein hsSUN1 and a membrane-associated histone acetyltransferase (HAT), hALP.

  15. NAT10 may play an important role in cell division through facilitating reformation of the nucleolus and midbody in the late phase of cell mitosis, and stabilization of microtubules.

NAT10 Protein Profile

Protein Summary

May have histone acetyltransferase (Potential).

Gene names and symbols associated with NAT10

  • N-acetyltransferase 10 (NAT10)
  • N-acetyltransferase 10 (Nat10)
  • N-acetyltransferase 10 (nat10)
  • N-acetyltransferase 10 (CC1G_12871)
  • N-acetyltransferase 10 (MCYG_05927)
  • N-acetyltransferase 10 (PITG_19671)
  • N-acetyltransferase 10 (MGYG_06040)
  • N-acetyltransferase 10 (GCN5-related) (nat10)
  • ribosome biogenesis ATPase (predicted) (SPAC20G8.09c)
  • hypothetical protein (nat10)
  • N-acetyltransferase 10 (GCN5-related) L homeolog (nat10.L)
  • AI429152 protein
  • ALP protein
  • DDBDRAFT_0190093 protein
  • DDBDRAFT_0234062 protein
  • DDB_0190093 protein
  • DDB_0234062 protein
  • NET43 protein
  • RGD1306717 protein
  • zgc:66119 protein

Protein level used designations for NAT10

N-acetyltransferase 10 , N-acetyltransferase-like protein , novel putative ATPase domain containing protein , N-acetyltransferase 10 (GCN5-related) , N-acetyltransferase Nat10 (predicted) , N-acetyltransferase 10-like , n-acetyltransferase 10-like

GENE ID SPECIES
55226 Homo sapiens
98956 Mus musculus
393617 Danio rerio
426609 Gallus gallus
483431 Canis lupus familiaris
515001 Bos taurus
6016175 Coprinopsis cinerea okayama7130
9224347 Arthroderma otae CBS 113480
9467098 Phytophthora infestans T30-4
10026747 Arthroderma gypseum CBS 118893
466485 Pan troglodytes
717452 Macaca mulatta
779537 Xenopus (Silurana) tropicalis
2542520 Schizosaccharomyces pombe 972h-
8616722 Dictyostelium discoideum AX4
100031449 Monodelphis domestica
100059185 Equus caballus
100174807 Xenopus laevis
100340636 Oryctolagus cuniculus
100386800 Callithrix jacchus
100460914 Pongo abelii
100474201 Ailuropoda melanoleuca
100511365 Sus scrofa
100543407 Meleagris gallopavo
100566182 Anolis carolinensis
100582525 Nomascus leucogenys
311257 Rattus norvegicus
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