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NAT5 is a component of N-acetyltransferase complex B (NatB). Additionally we are shipping N-Acetyltransferase 5 Antibodies (38) and N-Acetyltransferase 5 Kits (6) and many more products for this protein.
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The human NatB complex composed of Naa20 (NAT3) and Naa25 (MDM20) N-terminally acetylates Met-Glu-, Met-Asp-, Met-Asn- and Met-Gln- N-termini, and is important for the structure and function of actomyosin fibers and for proper cellular migration.
hNat3 (NAT5) is the catalytic subunit and hMdm20 the auxiliary subunit of the human NatB N-terminal acetyltransferase complex. This ribosome associated complex acetylates nascent Met-Asp/Glu- polypeptides.
Mdm20 is not necessarily co-expressed with Nat5 in the developing mouse brain.
ARD1 functions as an inhibitor of the mTOR pathway and that dysregulation of the ARD1-TSC2-mTOR axis may contribute to cancer development
NAT5 is a component of N-acetyltransferase complex B (NatB). Human NatB performs cotranslational N(alpha)-terminal acetylation of methionine residues when they are followed by asparagine (Starheim et al., 2008
N-acetyltransferase 3 homolog
, N-acetyltransferase 5 (ARD1 homolog, S. cerevisiae)
, N-acetyltransferase 5 (GCN5-related, putative)
, N-acetyltransferase 5, ARD1 subunit (arrest-defective 1, S. cerevisiae, homolog)
, N-alpha-acetyltransferase 20
, N-alpha-acetyltransferase 20, NatB catalytic subunit
, N-terminal acetyltransferase B complex catalytic subunit NAA20
, N-terminal acetyltransferase B complex catalytic subunit NAT5
, N-terminal acetyltransferase complex ARD1 subunit
, methionine N-acetyltransferase
, natB catalytic subunit
, natB complex subunit NAT5
, N-acetyltransferase 5