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NCF4 Proteins

(Neutrophil Cytosolic Factor 4, 40kDa (NCF4))
The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
NCF4 Protein (AA 1-339) (His tag) NCF4 Protein (AA 1-339) (His tag) NCF4 Protein (AA 1-339) (His tag) (ABIN7124162)

NCF4 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

NCF4 Protein (AA 1-339) (His tag) NCF4 Protein (AA 1-339) (His tag) NCF4 Protein (AA 1-339) (His tag) (ABIN3121165)

Crystallography grade NCF4 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

NCF4 Protein (AA 132-339) (His tag) (ABIN7415086)

NCF4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC

NCF4 Proteins by Grade

Find NCF4 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

NCF4 Proteins by Origin

Find NCF4 Proteins for a variety of species such as anti-Human NCF4, anti-Mouse NCF4. The species listed below are among those available. Click on a link to go to the corresponding products.

NCF4 Proteins by Source

Here you will find NCF4 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

NCF4 Proteins by Protein Type

Here you can find NCF4 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

NCF4 Proteins by Application

Find NCF4 Proteins validated for a specific application such as WB, ELISA, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular NCF4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124162
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3121165
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7415086
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7415035
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312099
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312101
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2726889
Quantity 20 μg
Datasheet Datasheet

Aliases for NCF4 Proteins

neutrophil cytosolic factor 4 (ncf4) Proteins
neutrophil cytosolic factor 4 (Ncf4) Proteins
neutrophil cytosolic factor 4 (NCF4) Proteins
AI451400 Proteins
NCF Proteins
p40phox Proteins
P40PHOX Proteins
SH3PXD4 Proteins
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