N-Acylaminoacyl-Peptide Hydrolase Proteins (APEH)

APEH encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. Additionally we are shipping APEH Antibodies (74) and APEH Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
APEH 327 P13798
APEH 24206 P13676
APEH 235606 Q8R146
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Top APEH Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,741.67
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,741.67
Details
Wheat germ Human GST tag 10 μg 11 to 12 Days
$340.00
Details
Yeast Rat His tag   1 mg 60 to 71 Days
$4,139.67
Details

APEH Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Rat (Rattus)

Mouse (Murine)

More Proteins for N-Acylaminoacyl-Peptide Hydrolase (APEH) Interaction Partners

Human N-Acylaminoacyl-Peptide Hydrolase (APEH) interaction partners

  1. Although APEH is primarily localized in the cytoplasm, a sub-fraction of this enzyme is sequestered at sites of nuclear damage following UVA irradiation or following oxidative stress. APEH interacts with the amino-terminal domain of XRCC1, and APEH facilitates both single-strand break repair and cell survival following exposure to H2O2. Thus, APEH as a novel proteolytic component of the DNA damage response.

  2. APEH polymorphism has significant influence on valproic acid pharmacokinetics in Chinese population

  3. Studies indicate that the cylindromatosis/turban tumor syndrome gene (CYLD) ranked highest, followed by acylaminoacyl-peptidase (APEH), dystroglycan (DAG1), macrophage-stimulating protein (MST1) and ubiquitin-specific peptidase 4 (USP4).

Pig (Porcine) N-Acylaminoacyl-Peptide Hydrolase (APEH) interaction partners

  1. His507 is an important residue that is probably involved in the formation of the 3-dimensional structure (acylaminoacyl peptidase)

  2. crystallographic analysis of porcine acylaminoacyl peptidase

APEH Protein Profile

Protein Summary

This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.

Gene names and symbols associated with APEH

  • acylaminoacyl-peptide hydrolase (APEH)
  • acylaminoacyl-peptide hydrolase (Apeh)
  • acylpeptide hydrolase (Apeh)
  • acylaminoacyl-peptide hydrolase (apeh)
  • AAP protein
  • AARE protein
  • ACPH protein
  • APH protein
  • cb5 protein
  • D3F15S2 protein
  • D3S48E protein
  • DNF15S2 protein
  • OPH protein
  • sb:cb5 protein
  • wu:fi37d02 protein

Protein level used designations for APEH

N-acylaminoacyl-peptide hydrolase , acyl-peptide hydrolase , acylamino-acid-releasing enzyme , acylaminoacyl-peptidase , oxidized protein hydrolase , AARE , APH , acylpeptide hydrolase , N-acylpeptide hydrolase , acylamino acid-releasing enzyme , acylaminoacyl peptidase , N-acylaminoacyl peptide hydrolase , Acyl-peptide hydrolase , Acylaminoacyl-peptidase , LOW QUALITY PROTEIN: acylamino-acid-releasing enzyme , acylamino-acid-releasing enzyme-like

GENE ID SPECIES
327 Homo sapiens
24206 Rattus norvegicus
396961 Sus scrofa
415926 Gallus gallus
476622 Canis lupus familiaris
100354109 Oryctolagus cuniculus
235606 Mus musculus
514666 Bos taurus
100333019 Danio rerio
100730493 Cavia porcellus
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