N-Acylethanolamine Acid Amidase Proteins (NAAA)

NAAA encodes an N-acylethanolamine-hydrolyzing enzyme which is highly similar to acid ceramidase. Additionally we are shipping NAAA Antibodies (43) and NAAA Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NAAA 27163 Q02083
NAAA 67111 Q9D7V9
NAAA 497009 Q5KTC7
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Top NAAA Proteins at antibodies-online.com

Showing 6 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
$5,370.21
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
$5,370.21
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
$6,749.58
Details
Escherichia coli (E. coli) Human His tag 100 μg 15 to 18 Days
$774.00
Details
Wheat germ Human GST tag 10 μg 11 to 12 Days
$414.29
Details
Yeast Rat His tag   1 mg 60 to 71 Days
$2,887.50
Details

NAAA Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine) ,

Rat (Rattus)

More Proteins for N-Acylethanolamine Acid Amidase (NAAA) Interaction Partners

Human N-Acylethanolamine Acid Amidase (NAAA) interaction partners

  1. Variants a1 and a2 encoded the same full-length NAAA protein.

  2. The results suggest that N-acylethanolamine acid amidase and protein tyrosine kinase 7 may be used as potential tissue biomarkers to avoid overtreatment of non-aggressive prostate cancer

  3. MALDI-TOF MS analysis of the human NAAA zymogen (47.7 kDa) treated with peptide-N-glycosidase F (PNGase F) identified 4 glycosylation sites, and acid cleavage of the zymogen into alpha- and beta-subunits (14.6 and 33.3 kDa) activated the enzyme.

  4. The level and activity of acid ceramidase in Alzheimer disease (AD) brain may play a role in controlling neuronal apoptosis and may mediate signalling pathways involved in the molecular mechanism of AD.

  5. Asn-37, Asn-107, Asn-309, and Asn-333 are actual N-glycosylation sites. The glycosylation appeared to play an important role in stabilizing the enzyme protein.

  6. we describe the overexpression and processing of recombinant human acid ceramidase in insect cells, its purification and characterization

  7. These results showed that both N-acylethanolamine-hydrolysing acid amidase and fatty acid amide hydrolase are functionally active in human prostate cancer cells.

Mouse (Murine) N-Acylethanolamine Acid Amidase (NAAA) interaction partners

  1. Both inhibitors reduced several markers of macrophage activation, such as mRNA expression of inflammatory mediators, as well as cytokine and prostaglandin production, with however some differences between FAAH and NAAA inhibition. Our results support an important role for inhibition of NAE hydrolysis and NAAA inhibition in particular in controlling macrophage activation, and thus inflammation.

  2. NAAA inhibition increases palmitoylethanolamide levels in the colon and reduces colon inflammation and systemic inflammation

  3. NAAA regulates peripheral pain initiation by interrupting endogenous fatty acid ethanolamide signaling at PPAR-alpha.

  4. Results suggest that N-acylethanolamine-hydrolyzing acid amidase and fatty acid amide hydrolase cooperatively degrade anandamide and other N-acylethanolamines in macrophages.

NAAA Protein Profile

Protein Summary

This gene encodes an N-acylethanolamine-hydrolyzing enzyme which is highly similar to acid ceramidase. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with NAAA

  • N-acylethanolamine acid amidase (NAAA)
  • N-acylethanolamine acid amidase (naaa)
  • N-acylethanolamine acid amidase L homeolog (naaa.L)
  • N-acylethanolamine acid amidase (Naaa)
  • 2210023K21Rik protein
  • 3830414F09Rik protein
  • Asahl protein
  • MGC88955 protein
  • NAAA protein
  • PLT protein

Protein level used designations for NAAA

N-acylsphingosine amidohydrolase (acid ceramidase)-like , N-acylethanolamine acid amidase , N-acylsphingosine amidohydrolase-like protein , N-acylethanolamine-hydrolyzing acid amidase-like , n-acylethanolamine-hydrolyzing acid amidase-like , ASAH-like protein , N-acylethanolamine-hydrolyzing acid amidase , acid ceramidase-like protein

GENE ID SPECIES
422641 Gallus gallus
448239 Xenopus (Silurana) tropicalis
700991 Macaca mulatta
739402 Pan troglodytes
100399529 Callithrix jacchus
100450814 Pongo abelii
100596863 Nomascus leucogenys
447407 Xenopus laevis
27163 Homo sapiens
515375 Bos taurus
67111 Mus musculus
497009 Rattus norvegicus
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