anti-N-Myc Downstream Regulated 1 (NDRG1) Antibodies

NDRG1 is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. Additionally we are shipping N-Myc Downstream Regulated 1 Proteins (17) and N-Myc Downstream Regulated 1 Kits (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NDRG1 10397 Q92597
NDRG1 17988 Q62433
NDRG1 299923 Q6JE36
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Top anti-N-Myc Downstream Regulated 1 Antibodies at antibodies-online.com

Showing 10 out of 195 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: NDRG1 Antibody [NBP1-86636] - Staining of human stomach shows strong cytoplasmic positivity in glandular cells. Western Blot: NDRG1 Antibody [NBP1-86636] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells); Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells). 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Mouse Un-conjugated ELISA, IF, IHC, WB Immunoperoxidase of monoclonal antibody to NDRG1 on formalin-fixed paraffin-embedded human endometrium (antibody concentration 0.7 µg/mL).  Detection limit for recombinant GST tagged NDRG1 is approximately 1 ng/mL as a capture antibody. 100 μg Log in to see 8 to 11 Days
$461.00
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN184872 staining (0.1µg/ml) of Human Kidney lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 6 to 7 Days
$358.02
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-NDRG1 Antibody Titration:  2.5ug/ml  Positive Control:  HepG2 cell lysate Rabbit Anti-NDRG1 Antibody   Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-NDRG1 Antibody Titration:  2.5ug/ml  Positive Control:  HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: NDRG1 Antibody [NBP1-32074] - A. 30 ug 293T whole cell lysate/extract, B. 30 ug HepG2 whole cell lysate/extract 10 % SDS-PAGE gel, antibody dilution 1:1000. Western Blot: NDRG1 Antibody [NBP1-32074] - Sample (30 ug of whole cell lysate) A:NIH-3T3 10% SDS PAGE diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Human Goat Un-conjugated IHC (p), IHC, ELISA, WB Immunohistochemistry-Paraffin: NDRG1 Antibody [ABIN268580] - (0.5ug/ml) staining of paraffin embedded Human hepatocelluar carcinoma. Data obtained from C. Furer, Visceral Surgery, University of Bern, Switzerland. Western Blot: NDRG1 Antibody [ABIN268580] - staining (1ug/ml) of Human Testis lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Rabbit Un-conjugated IF, IHC, WB Immunohistochemistry of paraffin-embedded mouse kidney using NDRG1 antibody at dilution of 1:100 (x400 lens). 100 μL Log in to see 16 Days
$334.02
Details
Human Goat Un-conjugated ELISA, IHC, IHC (p), WB Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 11 to 14 Days
$484.00
Details

Top referenced anti-N-Myc Downstream Regulated 1 Antibodies

  1. Human Polyclonal NDRG1 Primary Antibody for ICC, IF - ABIN4338332 : Schilling, Hjelmeland, Radiloff, Liu, Wakeman, Fielhauer, Foster, Lathia, Rich, Wang, Datto: NDRG4 is required for cell cycle progression and survival in glioblastoma cells. in The Journal of biological chemistry 2009 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal NDRG1 Primary Antibody for IF, IHC (p) - ABIN564518 : Leth-Larsen, Lund, Hansen, Laenkholm, Tarin, Jensen, Ditzel: Metastasis-related plasma membrane proteins of human breast cancer cells identified by comparative quantitative mass spectrometry. in Molecular & cellular proteomics : MCP 2009 (PubMed)
    Show all 2 Pubmed References

  3. Arabidopsis thaliana Polyclonal NDRG1 Primary Antibody for IHC - ABIN966642 : Century, Shapiro, Repetti, Dahlbeck, Holub, Staskawicz: NDR1, a pathogen-induced component required for Arabidopsis disease resistance. in Science (New York, N.Y.) 1997 (PubMed)
    Show all 2 Pubmed References

  4. Arabidopsis thaliana Polyclonal NDRG1 Primary Antibody for IHC - ABIN966641 : Coppinger, Repetti, Day, Dahlbeck, Mehlert, Staskawicz: Overexpression of the plasma membrane-localized NDR1 protein results in enhanced bacterial disease resistance in Arabidopsis thaliana. in The Plant journal : for cell and molecular biology 2004 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal NDRG1 Primary Antibody for IHC (p), IHC - ABIN268580 : Zhou, Salnikow, Costa: Cap43, a novel gene specifically induced by Ni2+ compounds. in Cancer research 1998 (PubMed)

  6. Human Polyclonal NDRG1 Primary Antibody for IHC, IHC (p) - ABIN442051 : Chaudhari, Talwar, Lefebvre Dhellencourt, Ravanan: CDDO and ATRA Instigate Differentiation of IMR32 Human Neuroblastoma Cells. in Frontiers in molecular neuroscience 1970 (PubMed)

More Antibodies against N-Myc Downstream Regulated 1 Interaction Partners

Human N-Myc Downstream Regulated 1 (NDRG1) interaction partners

  1. In summary, CAPE attenuates Nasopharyngeal carcinoma (NPC (show NPC1 Antibodies))cell proliferation and invasion by upregulating NDRG1 expression via MAPK (show MAPK1 Antibodies) pathway and by inhibiting phosphorylation of STAT3 (show STAT3 Antibodies). Considering the poor prognosis of NPC (show NPC1 Antibodies) patients with metastasis, CAPE could be a promising agent against NPC (show NPC1 Antibodies).

  2. These results indicate the N-terminus region and phosphorylation at Ser330 could be crucial for NDRG1 nuclear localization and function. PTEN silencing indicated that p-NDRG1 (Thr346) could be regulated differentially in different tumor cell-types, indicating PTEN may be involved in the mechanism(s) underlying the pleiotropic activity of NDRG1.

  3. present study shows that HER4 and/or NDRG1 might play a critical role for the cell survival and chemo-resistance of Osteosarcoma (OS), and could be used as potential therapeutic targets in OS.

  4. our study described two homozygous missense mutations in NDRG1 in CMT patients and mentioned the function of NDRG1 in protein recycling, which plays an important role in myelination of the peripheral nerve system.

  5. NDRG1 over-expression promoted apoptosis in colorectal cancer cells whereas depletion of NDRG1 resulted in resistance to oxaliplatin treatment.

  6. HCV coopts the MYC pathway responsible for NDRG1 expression and phosphorylation that regulates lipid droplet formation and metabolism. NDRG1 appears to restrict HCV by suppressing the lipid droplet formation that is necessary for HCV assembly.

  7. these data show that NDRG1 is regulated by the oncogenic MAP kinase (show MAPK1 Antibodies)-interacting kinase pathway, a target for cancer therapy

  8. The research findings provide novel insights suggesting that loss of N-myc downregulated gene 1 (NDRG1) leads to a decrease in actin-mediated cellular motility but an increase in cellular invasion, resulting in increased tumor dissemination which positively impacts metastatic outcome.

  9. Our experiments revealed that long-term (24 h), but not short-term hypoxia led to the induction of NDRG1 expression in human glioma cell lines. NDRG1 expression was found to correlate with the protein expression of HIF-1alpha (show HIF1A Antibodies), SP1 (show PSG1 Antibodies), CEBPalpha, YB-1 (show YBX1 Antibodies) and Smad7 (show SMAD7 Antibodies)

  10. Data show that LSD1 affects motility and invasiveness of neuroblastoma cells by modulating the transcription of the metastasis suppressor NDRG1. Mechanistically, results found that LSD1 co-localizes with MYCN at the promoter region of the NDRG1 gene and inhibits its expression.

Mouse (Murine) N-Myc Downstream Regulated 1 (NDRG1) interaction partners

  1. NDR1 interacts with TRAF3 and interferes with the association of TRAF3 and IL-17R, resulting in increased formation of the activation complex IL-17R-Act1, which is required for the downstream signaling and production of pro-inflammatory factors

  2. NDR1 (show STK38 Antibodies) kinase, activated by the Rap1 (show TERF2IP Antibodies) signaling cascade through RAPL (show RASSF5 Antibodies) and Mst1 (show MST1 Antibodies)/Mst2 (show STK3 Antibodies), associated with and recruited kindlin-3 (show FERMT3 Antibodies) to the immunological synapses, which was required for high-affinity LFA-1 (show ITGAL Antibodies)/ICAM-1 (show ICAM1 Antibodies) binding.

  3. Snell, GHKRO, and PAPPA (show PAPPA Antibodies)-KO mice express high levels of two proteins involved in DNA repair, O-6-methylguanine-DNA methyltransferase (MGMT (show MGMT Antibodies)) and N-myc downstream-regulated gene 1 (NDRG1).

  4. NDRG1 deficiency attenuates the differentiation of macrophage lineage cells, suppressing bone remodeling and inflammatory angiogenesis. This study strongly suggests the crucial role of NDRG1 in differentiation process for macrophages.

  5. Using double knockout of NDR1 (show STK38 Antibodies) and 2 shows that NDRs acted downstream of MST1 (show MST1 Antibodies) to mediate the egress of mature thymocytes from the thymus, as well as the interstitial migration of naive T cells within popliteal lymph nodes.

  6. Ndrg1 is phosphorylated and degraded by CD28 (show CD28 Antibodies) signalling in a proteasome-dependent manner.

  7. Ndr1 (show STK38 Antibodies)/2-double null embryos show defects in somitogenesis and cardiac looping, which reveals their essential functions and shows that the NDR (show STK38 Antibodies) kinases are critically required during the early phase of organogenesis

  8. Rassf5 (show RASSF5 Antibodies) and Ndr1 (show STK38 Antibodies) or Ndr2 (show STK38L Antibodies) kinases regulate neuronal polarity through Par3 (show F2RL2 Antibodies) phosphorylation.

  9. NDRG1 promotes fetal growth and regulates the metabolic response to intrauterine hypoxic injury in a sexually dichotomous manner

  10. early growth response 1 (show EGR1 Antibodies), a transcription factor that binds to the NDRG1 promoter, was mediated in the NDRG1 expression regulation by PKD2 (show PKD2 Antibodies).

Zebrafish N-Myc Downstream Regulated 1 (NDRG1) interaction partners

  1. ndrg1b and fam49ab are 2 new modulators of PTEN signaling that control lymphoid differentiation in the zebrafish thymus.

Arabidopsis thaliana N-Myc Downstream Regulated 1 (NDRG1) interaction partners

  1. NDR1 plays a broad role both in mediating primary cellular functions in Arabidopsis through maintaining the integrity of the cell wall-plasma membrane connection and as a key signaling component of these responses during pathogen infection.

  2. SR1 plays an important role in plant immunity and ethylene signaling by directly regulating NDR1 and EIN3.

  3. The induction of defence responses and disease resistance to X. campestris pv. campestris strain 8004 requires NDR1 , RAR1 and SGT1b, suggesting that effector-triggered immunity plays a large role in resistance to this strain.

  4. Sequence analysis and mass spectrometry suggest that NDR1 (show STK38 Antibodies) is localized to the PM via a C-terminal glycosylphosphatidyl-inositol (GPI (show GPI Antibodies)) anchor.

  5. demonstrate that the RIN4-NDR1 interaction occurs on the cytoplasmically localized N-terminal portion of NDR1 and that this interaction is required for the activation of resistance signaling following infection by P. syringae

  6. Mutations in NDR1 (show STK38 Antibodies) abolished the enhanced resistance of dnd (show DND1 Antibodies) mutants against Pseudomonas syringae pv. tomato and Hyaloperonospora parasitica but not Botrytis cinerea.

N-Myc Downstream Regulated 1 (NDRG1) Antigen Profile

Protein Summary

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with NDRG1

  • N-myc downstream regulated 1 (NDRG1) antibody
  • N-myc downstream regulated gene 1 (Ndrg1) antibody
  • N-myc downstream regulated 1 (Ndrg1) antibody
  • N-myc downstream regulated 1 S homeolog (ndrg1.S) antibody
  • N-myc downstream regulated 1 (ndrg1) antibody
  • N-myc downstream regulated 1a (ndrg1a) antibody
  • Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family (NDR1) antibody
  • N-myc downstream regulated 1 L homeolog (ndrg1.L) antibody
  • N-myc downstream regulated 1b (ndrg1b) antibody
  • cap43 antibody
  • cb775 antibody
  • cmt4d antibody
  • DRG-1 antibody
  • drg1 antibody
  • gc4 antibody
  • hmsnl antibody
  • ndr1 antibody
  • NDRG1 antibody
  • ndrg1-a antibody
  • ndrg1-b antibody
  • ndrg1l antibody
  • ndrg4 antibody
  • Ndrl antibody
  • nmsl antibody
  • NON-RACE SPECIFIC DISEASE RESISTANCE PROTEIN antibody
  • non race-specific disease resistance 1 antibody
  • proxy1 antibody
  • rit42 antibody
  • rtp antibody
  • targ1 antibody
  • tdd5 antibody
  • wu:fb60h02 antibody
  • xndrg1 antibody
  • xNDRG1-A antibody
  • zgc:63944 antibody
  • zgc:73047 antibody

Protein level used designations for NDRG1

N-myc downstream-regulated gene 1 protein , differentiation-related gene 1 protein , nickel-specific induction protein Cap43 , protein NDRG1 , protein regulated by oxygen-1 , reducing agents and tunicamycin-responsive protein , N-myc downstream regulated 1 , protein Ndr1 , N-myc downstream regulated gene 1 , protein NDRG1-B , xNDRG1-B , protein NDRG1-like , protein NDRG1-A , xNDRG1-A , N-myc downstream regulated gene 1, like , N-myc downstream regulated gene 1b , n-myc downstream-regulated gene 1b

GENE ID SPECIES
10397 Homo sapiens
17988 Mus musculus
299923 Rattus norvegicus
380319 Xenopus laevis
420321 Gallus gallus
464411 Pan troglodytes
482049 Canis lupus familiaris
493508 Xenopus (Silurana) tropicalis
504499 Bos taurus
792085 Danio rerio
100068997 Equus caballus
100230327 Taeniopygia guttata
100401077 Callithrix jacchus
100466806 Ailuropoda melanoleuca
100596235 Nomascus leucogenys
697752 Macaca mulatta
821607 Arabidopsis thaliana
100728790 Cavia porcellus
447720 Xenopus laevis
393665 Danio rerio
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