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The protein encoded by NDUFB2 is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I).
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NADH:ubiquinone oxidoreductase (show TXNRD1 Antibodies) gene may have a role in the regulation of molecular changes during the global cardiac ischemia/reperfusion injury during CPB (show CPB1 Antibodies)
The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays a important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Hydropathy analysis revealed that this subunit and 4 other subunits have an overall hydrophilic pattern, even though they are found within the hydrophobic protein (HP) fraction of complex I.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial
, NADH-ubiquinone oxidoreductase AGGG subunit
, complex I-AGGG
, complex I AGGG subunit