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The protein encoded by NDUFS1 belongs to the complex I 75 kDa subunit family. Additionally we are shipping NDUFS1 Antibodies (80) and NDUFS1 Kits (6) and many more products for this protein.
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The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene.
, NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
, complex I-75kD
, NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa
, complex I 75kDa subunit
, complex I, mitochondrial respiratory chain, 75-kD subunit
, mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit