NDUFS1 Proteins

Protein Summary

The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with NDUFS1

• NADH dehydrogenase (ubiquinone) Fe-S protein 1 (Ndufs1) antibody
• NADH:ubiquinone oxidoreductase core subunit S1 (Ndufs1) antibody
• NADH:ubiquinone oxidoreductase core subunit S1 (NDUFS1) antibody

• 5830412M15Rik antibody
• 9930026A05Rik antibody
• CI-75k antibody
• CI-75Kd antibody
• PRO1304 antibody

Protein level used designations for NDUFS1

CI-75kD , NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial , complex I-75kD , NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa , complex I 75kDa subunit , complex I, mitochondrial respiratory chain, 75-kD subunit , mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit