NUAK1 Proteins

Serine/threonine-protein kinase involved in various processes such as cell adhesion, regulation of cell ploidy and senescence, cell proliferation and tumor progression.

Data Quality
  • 8
Type
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    Protein
Antigen
  • 9
Reactivity
  • 7
  • 2
Application
  • 6
  • 6
  • 6
  • 3
  • 2
Host
  • 5
  • 2
  • 2
Binding Specificity
  • 4
  • 1
  • 1
  • 1
  • 1
Conjugate
  • 4
  • 2
  • 1
  • 1
  • 1
Protein Type
  • 9
Format
  • 5
Biological Activity
  • 1
9 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3094295
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3135583
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
ReactivityHuman
Application Func, SDS
Order details Cat. No. ABIN5569713
$516.00
5 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application Func, SDS
Order details Cat. No. ABIN5569712
$1,502.67
100 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1313129
$338.33
2 μg
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1313130
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity ≥ 98 %
ReactivityHuman
Application ELISA, IP, SDS, WB
Order details Cat. No. ABIN4990973
$656.00
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity ≥ 90 %
ReactivityMouse (Murine)
Application ELISA, IP, SDS, WB
Order details Cat. No. ABIN4990974
$688.00
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
Recombinant Protein, Insect Cells (Source), Purity 70 % - 90 %
ReactivityHuman
Application Func
Order details Cat. No. ABIN5509049
$340.00
10 μg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
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NUAK1 Protein Profile

Protein Summary

Serine/threonine-protein kinase involved in various processes such as cell adhesion, regulation of cell ploidy and senescence, cell proliferation and tumor progression. Phosphorylates ATM, CASP6, LATS1, PPP1R12A and p53/TP53. Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1, thereby controlling its stability. Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex. Acts by mediating PPP1R12A then interacts with 14-3-3, leading to reduced dephosphorylation of myosin MLC2 by myosin PP1. May be involved in 392' and is recruited to the CDKN1A/WAF1 promoter to participate to transcription activation by p53/TP53. May also act as a tumor malignancy-associated factor by promoting tumor invasion and metastasis under regulation and phosphorylation by AKT1. Suppresses Fas-induced apoptosis by mediating phosphorylation of CASP6, thereby suppressing the activation of the caspase and the subsequent cleavage of CFLAR.

Gene names and symbols associated with NUAK1

  • NUAK family kinase 1 (NUAK1) antibody
  • NUAK family, SNF1-like kinase, 1 (Nuak1) antibody
  • ARK5 antibody
  • AU014801 antibody
  • AW494241 antibody
  • B230104P22Rik antibody
  • Omphk1 antibody

Protein level used designations for NUAK1

AMP-activated protein kinase family member 5 , AMPK-related protein kinase 5 , NUAK family SNF1-like kinase 1 , omphalocele kinase 1 , ZNUAK family, SNF1-like kinase, 1

GENE ID SPECIES
9891 Homo sapiens
77976 Mus musculus