anti-Nestin (NES) Antibodies

NES encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells. Additionally we are shipping Nestin Kits (35) and Nestin Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NES 10763 P48681
NES 18008 Q6P5H2
NES 25491 P21263
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Top anti-Nestin Antibodies at

Showing 10 out of 267 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Mouse FITC ICC, IF 50 μL 7 to 8 Days
Human Rabbit Un-conjugated IHC (p), WB Nestin was detected in paraffin-embedded sections of human melanoma tissues using rabbit anti- Nestin Antigen Affinity purified polyclonal antibody at 1 μg/mL. The immunohistochemical section was developed using SABC method Nestin was detected in paraffin-embedded sections of rat kidney tissues using rabbit anti- Nestin Antigen Affinity purified polyclonal antibody at 1 μg/mL. The immunohistochemical section was developed using SABC method 100 μg 4 to 6 Days
Cow Rabbit Un-conjugated IHC, WB 100 μL 2 to 3 Days
Mouse Rabbit Un-conjugated IF, WB 100 μL 13 to 14 Days
Mouse Rabbit Un-conjugated FACS, IF (p), IHC (p) Formalin-fixed and paraffin embedded rat brain labeled with Anti-Nestin Polyclonal Antibody (ABIN723530), Unconjugated 1:300 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat hippocampus labeled with Anti-Nestin Polyclonal Antibody (ABIN723530), Unconjugated 1:300 followed by conjugation to the secondary antibody and DAB staining 100 μL 3 to 7 Days
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of Nestin Antibody (S1409) (ABIN388764) in HepG2 cell line lysates (35 µg/lane). NES (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with Nestin Antibody (S1409), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL 10 to 11 Days
Mouse Rat Un-conjugated ICC, IHC 100 μg 9 to 11 Days
Human Rabbit Un-conjugated EIA, FACS, IF, IHC (p), WB   0.4 mL 4 to 8 Days
Human Rabbit Un-conjugated IHC, ELISA, WB Immunohistochemistry with anti-nestin antibody showing nestin staining in cytoplasm of of ductal epithelium of human salivary gland (B) and in nucleus and cytoplasm of human breast tissue (C). Formalin fixed/paraffin embedded sections were subjected to heat induced epitope retrieval (HIER) at pH 6.2 and then incubated with rabbit anti-nestin antibody at 4.0 µg/ml for 60 minutes. The reaction was developed using MACH 1 universal HRP polymer detection system and visualized with 3’3-diamino-benzidine substrate (DAB). Immunohistochemistry with Anti-nestin antibody Tissue: mouse kidney (Left) and human kidney (Right). Fixation: formalin-fixed, paraffin-embedded tissue Antigen retrieval: heat-induced Primary antibody: 5 µg/ml Staining: antibody as precipitated red signal with a hematoxylin purple nuclear counterstain. 100 μg 5 to 7 Days
Human Mouse Un-conjugated ICC, IHC, IHC (fro), IHC (p), WB Anti-Nestin antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959423 concentration 10 ug/ml. 0.05 mg 11 to 14 Days

Top referenced anti-Nestin Antibodies

  1. Human Monoclonal Nestin Primary Antibody for CyTOF, FACS - ABIN4900824 : Lee, Graham, Collins, Lee, Hong, Mcnicol, Shapovalova, Bhatia: Reversible lineage-specific priming of human embryonic stem cells can be exploited to optimize the yield of differentiated cells. in Stem cells (Dayton, Ohio) 2015 (PubMed)
    Show all 62 Pubmed References

  2. Human Polyclonal Nestin Primary Antibody for ICC, IF - ABIN151151 : Shi, Cui, Alam, Gunning, Nestor, Giovannucci, Zhang, Ding: Nestin expression defines both glial and neuronal progenitors in postnatal sympathetic ganglia. in The Journal of comparative neurology 2008 (PubMed)
    Show all 36 Pubmed References

  3. Human Polyclonal Nestin Primary Antibody for IHC (p), WB - ABIN3044529 : Bin, Ma, Xu, Shi: Embryonic hepatocyte transplantation for hepatic cirrhosis: efficacy and mechanism of action. in World journal of gastroenterology 2012 (PubMed)
    Show all 18 Pubmed References

  4. Human Monoclonal Nestin Primary Antibody for CyTOF, FACS - ABIN152605 : Gangemi, Griffero, Marubbi, Perera, Capra, Malatesta, Ravetti, Zona, Daga, Corte: SOX2 silencing in glioblastoma tumor-initiating cells causes stop of proliferation and loss of tumorigenicity. in Stem cells (Dayton, Ohio) 2009 (PubMed)
    Show all 16 Pubmed References

  5. Human Monoclonal Nestin Primary Antibody for ICC, IHC (fro) - ABIN335378 : Messam, Hou, Berman, Major: Analysis of the temporal expression of nestin in human fetal brain derived neuronal and glial progenitor cells. in Brain research. Developmental brain research 2002 (PubMed)
    Show all 10 Pubmed References

  6. Human Monoclonal Nestin Primary Antibody for ICC, IF - ABIN4338652 : Moncla, Chappell, Debo, Meyn: The Effects of Hormones and Vaginal Microflora on the Glycome of the Female Genital Tract: Cervical-Vaginal Fluid. in PLoS ONE 2016 (PubMed)
    Show all 8 Pubmed References

  7. Mouse (Murine) Monoclonal Nestin Primary Antibody for FACS - ABIN4897663 : Hu, Rotschafer, Lokensgard, Cheeran: Activated CD8+ T lymphocytes inhibit neural stem/progenitor cell proliferation: role of interferon-gamma. in PLoS ONE 2014 (PubMed)
    Show all 6 Pubmed References

  8. Human Monoclonal Nestin Primary Antibody for FACS - ABIN4898756 : Fusi, Reichelt, Busse, Ochsenreither, Rietz, Maisel, Keilholz: Expression of the stem cell markers nestin and CD133 on circulating melanoma cells. in The Journal of investigative dermatology 2011 (PubMed)
    Show all 6 Pubmed References

  9. Human Polyclonal Nestin Primary Antibody for ICC, IF - ABIN314945 : Ohnishi, Iwatsuki, Shinzawa, Ishihara, Moriwaki, Umegaki, Kishima, Yoshimine: Adult olfactory sphere cells are a source of oligodendrocyte and Schwann cell progenitors. in Stem cell research 2013 (PubMed)
    Show all 4 Pubmed References

  10. Human Polyclonal Nestin Primary Antibody for IF, IHC - ABIN187958 : Tchaicha, Mobley, Hossain, Aldape, McCarty: A mosaic mouse model of astrocytoma identifies alphavbeta8 integrin as a negative regulator of tumor angiogenesis. in Oncogene 2010 (PubMed)
    Show all 4 Pubmed References

More Antibodies against Nestin Interaction Partners

Human Nestin (NES) interaction partners

  1. FOXA1 was expressed mostly in ER-positive breast cancer metastases. Expression of Nestin was related to triple-negative metastases, where brain was the most frequent metastatic site. These findings highlight the clinical utility of FOXA1 and Nestin expression and warrant their inclusion in routine immunohistochemical panels for breast carcinoma.

  2. tyrosinase and nestin immunohistochemical expression in melanocytic nevi as a histopathologic pattern to trace melanocyte differentiation and nevogenesis

  3. Nestin immunohistochemical positivity is associated with the poor clinical outcomes and reduced survival rates in breast cancer patients that characterize the gene expression basal-like subtype.

  4. Nestin stabilizes lamin A-C for maintaining nuclear integrity and protecting tumor cells from senescence.

  5. We found an increased expression of Nestin and GAP43 (growth associated protein 43) in treated cells. In conclusion, Periodontal ligament mesenchymal stem cells (hPDLSCs) treated with Moringin and Cannabidiol showed an improved survival capacity and neuronal differentiation potential

  6. Melatonin disturbs SUMOylation-mediated crosstalk between c-Myc and nestin via MT1 activation and promotes the sensitivity of paclitaxel in brain cancer stem cells.

  7. Data indicated that nestin regulated NF-kappa B (NF-kappaB) activity in foetal spinal cord tissues.

  8. Nestin, originally identified as a marker of neural stem cells, was demonstrated to be expressed in breast cancer (BC). In normal breast tissue, nestin is expressed in the basal/myoepithelial cells. In BC, nestin identifies basal-like tumors and predicts aggressive behavior and poor prognosis. Also, it is been detected in BC stem cells and newly-formed tumor vessels promoting invasion and metastasis. [review]

  9. This review presents the current knowledge on the role of Nestin in essential stem cell functions, including self-renewal/proliferation, differentiation and migration, in the context of the cytoskeleton. [review]

  10. Results showed that nestin was expressed in various tissues of the embryo in patients with placenta previa, and nestin expression decreased as the embryo matured.

  11. In summary, Nestin was strongly associated with germline BRCA1 related breast cancer, a basal-like phenotype, reduced survival, and stemness characteristics.

  12. this meta-analysis indicated both CD133 and Nestin expression were significantly associated with advanced FIGO stage, larger size of residual cancer in EOC patients.

  13. Nestin expression in breast tumour cells is associated with enhanced angiogenesis and poor prognosis.

  14. results suggest that nestin might be a reliable marker for angiogenesis evaluation in patients with colorectal cancer. In contrast to CD34, the expression of nestin in blood vessels seems to be a more sensitive marker of cancer progression

  15. Benign and borderline lesions more frequently than malignant ovarian tumors displayed low or medium values of nestin-positive microvessel density. Significant correlations between PDGF-B and nestin expression in malignant tumor microvessels were also found.

  16. Nestin silencing inhibits proliferation and migration of malignant melanoma cells via G1/S arrest in a Akt-GSK3beta-Rb pathway.

  17. In this study demonstrated persistence of nestin-expressing cells in a stereotypical pattern. Striking observations included chains or rows of nestin-expressing cell in hippocampus and temporal lobe.

  18. Nestin expression was significantly higher in large cell neuroendocrine carcinomas.

  19. nestin expression in vessels was associated with a shorter overall survival (OS) and earlier relapse, and in the case of OS nestin was an independent prognostic factor. Finally, we further confirmed that nestin expression in endothelial cells reflects a progenitor nature of newly forming vessels.

  20. nestin may be a novel therapeutic target for tumor angiogenesis and a combination therapy that includes nestin-targeting agents may be an effective therapeutic approach. In addition, detection of Nestin/stem cells and Nestin/MVD can be used as predictors of disease

Mouse (Murine) Nestin (NES) interaction partners

  1. results show that a Nestin-Cdk5-Drp1 axis negatively regulates mitochondrial OXPHOS, which is indispensable for the maintenance of NSPC stemness.

  2. nestin plays a seminal role in the cell cycle re-entry of cardiomyocytes.

  3. results give new insights into the yet underestimated role of proliferating nestin-expressing vascular SMCs during postnatal development and repair of the epididymis.

  4. Nestin silencing inhibits proliferation and migration of malignant melanoma cells via G1/S arrest in a Akt-GSK3beta-Rb pathway.

  5. In mouse neural stem spheres and neuronal precursors, nestin expression was increased in morphine treated cells whereas it was downregulated in both HAT inhibitor and HAT inhibitor in combination with morphine.

  6. These results indicate that the first intron enhancer may be activated in differentiated odontoblasts. Intriguingly, Nestin-GFP expression in the subodontoblastic layer was found to be restricted to the coronal pulp of molars, which is susceptible to tooth injuries.

  7. These results reveal that nestin deficiency generates a spontaneous regenerative phenotype in skeletal muscle that relates to a disturbed proliferation cycle that is associated with uncontrolled Cdk5 activity.

  8. Nestin promotesneural progenitor cells (NPCs) proliferation via p38-MAPK and EGFR pathways, and reveals the necessity of these pathways in NPCs self-renewal.

  9. the loss of Nestin(+) cells might be an etiology to DCM pathogenesis, and these cells could be a promising candidate cell source for study and treatment of DCM patients

  10. Nestin regulates neural stem cell migration via controlling the cell contractility

  11. demonstrate that following postnatal ablation of granule cell progenitors, Nestin-expressing progenitors, specified during mid-embryogenesis to produce astroglia and interneurons, switch their fate and generate granule neurons in mice.

  12. The nestin(+) cells contribute to all subsets of the complex stromal populations that can be found in lymph nodes.

  13. nestin may label progenitor cells during inner ear development and may not be a stem cell marker in the mature organ of Corti

  14. Nestin(+) cells are one important type of progenitor cell in bone marrow and are associated with bone remodeling. These data indicate that DMP1 plays negative roles in differentiation of Nestin(+) cells and bone formation.

  15. Our findings show how Nestin drives hedgehog pathway-driven cancers and the tumor-promoting effects of Nestin were mediated by binding to Gli3, a zinc finger transcription factor that negatively regulates hedgehog signaling.

  16. Based on a nestin-green fluorescent protein (NGFP) transgenic model, a histological inventory has been performed to deliver an overview of neuronal and glial markers for the various parts of the gastrointestinal tract in newborn (postnatal day 7) and adult mice under homeostatic conditions.

  17. EGFR and Nestin showed to have vital role during mice development, and considered to be suitable markers for the study of skin stem cells.

  18. Nestin was shown to affect cell number and was significantly enhanced in lungs early during development of pulmonary hypertension.

  19. We show that their primary processes follow a tortuous path from the subgranular zone through the granule cell layer and ensheathe local synapses and vasculature in the inner molecular layer.

  20. Chromatin Remodeling Factor Brg1 Supports the Early Maintenance and Late Responsiveness of Nestin-Lineage Adult Neural Stem and Progenitor Cells.

Zebrafish Nestin (NES) interaction partners

  1. Morphine increases GFP in nestin:GFP embryos and overexpresses the NSC marker Nestin. Morphine also exerts a hyperacetylation effect on H3K27 and decreases DNA methylation in a region 18 Kb upstream of the nestin transcription starting site. A binding site for the transcription factor complex Sox2/Oct4/Nanog was predicted.

  2. Nestin gene may serve as a marker for stem cells and proliferating precursors in the developing embryonic nervous system as well as in the postembryonic brain[Nestin]

  3. Results suggest that nestin is essential for brain and eye development probably through control of progenitor cell apoptosis.

  4. Cells expressing the two reporters display radial glial morphology, colocalize with the NSC marker Sox2, undergo proliferation, and are capable of self-renewal within the matrix of distinct thickness in the telencephalon.

Nestin (NES) Antigen Profile

Protein Summary

This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells.

Gene names and symbols associated with anti-Nestin (NES) Antibodies

  • nestin (NES) antibody
  • nestin S homeolog (nes.S) antibody
  • nestin (Nes) antibody
  • nestin (nes) antibody
  • AA166324 antibody
  • C78523 antibody
  • ESTM46 antibody
  • NES antibody
  • paranemin antibody

Protein level used designations for anti-Nestin (NES) Antibodies

transitin , tanabin , nestin , nestin-like , intermediate filament protein

742303 Pan troglodytes
395890 Gallus gallus
397776 Xenopus laevis
100064419 Equus caballus
100409695 Callithrix jacchus
100456772 Pongo abelii
100472137 Ailuropoda melanoleuca
100584337 Nomascus leucogenys
10763 Homo sapiens
18008 Mus musculus
25491 Rattus norvegicus
490410 Canis lupus familiaris
522383 Bos taurus
100008641 Oryctolagus cuniculus
100150939 Danio rerio
101843961 Mesocricetus auratus
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