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NES encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells. Additionally we are shipping Nestin Kits (30) and Nestin Proteins (7) and many more products for this protein.
Showing 10 out of 309 products:
Human Monoclonal Nestin Primary Antibody for CyTOF, FACS - ABIN4900824
Lee, Graham, Collins, Lee, Hong, Mcnicol, Shapovalova, Bhatia: Reversible lineage-specific priming of human embryonic stem cells can be exploited to optimize the yield of differentiated cells. in Stem cells (Dayton, Ohio) 2015
Show all 46 Pubmed References
Human Polyclonal Nestin Primary Antibody for ICC, IF - ABIN151151
Shi, Cui, Alam, Gunning, Nestor, Giovannucci, Zhang, Ding: Nestin expression defines both glial and neuronal progenitors in postnatal sympathetic ganglia. in The Journal of comparative neurology 2008
Show all 29 Pubmed References
Human Monoclonal Nestin Primary Antibody for CyTOF, FACS - ABIN152605
Gangemi, Griffero, Marubbi, Perera, Capra, Malatesta, Ravetti, Zona, Daga, Corte: SOX2 silencing in glioblastoma tumor-initiating cells causes stop of proliferation and loss of tumorigenicity. in Stem cells (Dayton, Ohio) 2009
Show all 12 Pubmed References
Rat (Rattus) Monoclonal Nestin Primary Antibody for FM, FACS - ABIN967492
Dahlstrand, Collins, Lendahl: Expression of the class VI intermediate filament nestin in human central nervous system tumors. in Cancer research 1992
Show all 9 Pubmed References
Human Monoclonal Nestin Primary Antibody for ICC, IHC (fro) - ABIN335378
Messam, Hou, Berman, Major: Analysis of the temporal expression of nestin in human fetal brain derived neuronal and glial progenitor cells. in Brain research. Developmental brain research 2002
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Human Monoclonal Nestin Primary Antibody for IF, WB - ABIN968628
Jin, Zhu, Sun, Mao, Xie, Greenberg: Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo. in Proceedings of the National Academy of Sciences of the United States of America 2002
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Human Monoclonal Nestin Primary Antibody for IF, WB - ABIN968629
Kernie, Erwin, Parada: Brain remodeling due to neuronal and astrocytic proliferation after controlled cortical injury in mice. in Journal of neuroscience research 2001
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Human Monoclonal Nestin Primary Antibody for ICC, IF - ABIN4338652
Moncla, Chappell, Debo, Meyn: The Effects of Hormones and Vaginal Microflora on the Glycome of the Female Genital Tract: Cervical-Vaginal Fluid. in PLoS ONE 2016
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Mouse (Murine) Monoclonal Nestin Primary Antibody for FACS - ABIN4897663
Hu, Rotschafer, Lokensgard, Cheeran: Activated CD8+ T lymphocytes inhibit neural stem/progenitor cell proliferation: role of interferon-gamma. in PLoS ONE 2014
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Mouse (Murine) Polyclonal Nestin Primary Antibody for FACS, IF (p) - ABIN723530
Yamamizu, Fujihara, Tachibana, Katayama, Takahashi, Hara, Imai, Shinkai, Yamashita: Protein kinase A determines timing of early differentiation through epigenetic regulation with G9a. in Cell stem cell 2012
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nestin may be a novel therapeutic target for tumor angiogenesis and a combination therapy that includes nestin-targeting agents may be an effective therapeutic approach. In addition, detection of Nestin/stem cells and Nestin/MVD (show MVD Antibodies) can be used as predictors of disease
Knockdown of Nestin significantly reduced tumor volume in vivo.
Nestin plays an important role in the prediction of the clinicopathology and poor prognosis of glioma patients.
The authors found that high/positive SOX2 (show SOX2 Antibodies) alterations, either DNA amplification or protein expression, were favorable for overall survival (OS) in non-small cell lung cancer. On the contrary, high/positive Nestin protein expression was poor for OS.
Study clarified the relationship between Nestin overexpression and poor prognosis in recurrent human hepatocellular carcinoma (HCC (show FAM126A Antibodies)) patients receiving FOLFOX regimen, and its association with chemoresistance and epithelial-mesenchymal transition in HCC (show FAM126A Antibodies) cell lines.
Results show that the positive rates and expression levels of nestin, tyrosine hydroxylase (TH (show TH Antibodies)), GFAP (show GFAP Antibodies) and IL-17 (show IL17A Antibodies) were significantly decreased while Foxp3 (show FOXP3 Antibodies) and the ratio of Foxp3 (show FOXP3 Antibodies)/IL-17 (show IL17A Antibodies) were statistically elevated in BM of AML (show RUNX1 Antibodies) patients.
Nestin may have an important role in GIST malignancy by regulating mitochondrial dynamics and altering intracellular ROS (show ROS1 Antibodies) levels. The findings provide new clues to reveal mechanisms by which nestin mediates the proliferation and invasion of GISTs.
he present study reveals that nestin expression is a prognostic indicator of a poorer survival probability in NSCLC patients receiving adjuvant platinum-based chemotherapy , although its prognostic significance still requires confirmation with larger patient populations
Data suggest that negative feedback mediated by GLI3 (show GLI3 Antibodies) (GLI (show GLI1 Antibodies)-Kruppel family member) acts to finely tune SHH (sonic hedgehog (show SHH Antibodies)) signaling. During medulloblastoma (MB) formation, nerve tissue cells appear to express nestin which hyperactivates SHH (show SHH Antibodies) signaling by abolishing negative feedback by GLI3 (show GLI3 Antibodies). Restoration of intrinsic negative feedback by repressing nestin expression represents a promising approach to treat MB. [REVIEW]
the induction of P-gp (show ABCB4 Antibodies) expression is causally associated with the expression of nestin in leukemia cells
These results reveal that nestin deficiency generates a spontaneous regenerative phenotype in skeletal muscle that relates to a disturbed proliferation cycle that is associated with uncontrolled Cdk5 (show CDK5 Antibodies) activity.
Nestin promotesneural progenitor cells (NPCs) proliferation via p38-MAPK (show MAPK14 Antibodies) and EGFR (show EGFR Antibodies) pathways, and reveals the necessity of these pathways in NPCs self-renewal.
the loss of Nestin(+) cells might be an etiology to DCM pathogenesis, and these cells could be a promising candidate cell source for study and treatment of DCM patients
Nestin regulates neural stem cell migration via controlling the cell contractility
demonstrate that following postnatal ablation of granule cell progenitors, Nestin-expressing progenitors, specified during mid-embryogenesis to produce astroglia and interneurons, switch their fate and generate granule neurons in mice.
The nestin(+) cells contribute to all subsets of the complex stromal populations that can be found in lymph nodes.
nestin may label progenitor cells during inner ear development and may not be a stem cell marker in the mature organ of Corti
Nestin(+) cells are one important type of progenitor cell in bone marrow and are associated with bone remodeling. These data indicate that DMP1 (show DMP1 Antibodies) plays negative roles in differentiation of Nestin(+) cells and bone formation.
Our findings show how Nestin drives hedgehog (show SHH Antibodies) pathway-driven cancers and the tumor-promoting effects of Nestin were mediated by binding to Gli3 (show GLI3 Antibodies), a zinc finger transcription factor (show OSR1 Antibodies) that negatively regulates hedgehog (show SHH Antibodies) signaling.
Based on a nestin-green fluorescent protein (NGFP) transgenic model, a histological inventory has been performed to deliver an overview of neuronal and glial markers for the various parts of the gastrointestinal tract in newborn (postnatal day 7) and adult mice under homeostatic conditions.
Nestin gene may serve as a marker for stem cells and proliferating precursors in the developing embryonic nervous system as well as in the postembryonic brain[Nestin]
Results suggest that nestin is essential for brain and eye development probably through control of progenitor cell apoptosis.
Cells expressing the two reporters display radial glial morphology, colocalize with the NSC marker Sox2 (show SOX2 Antibodies), undergo proliferation, and are capable of self-renewal within the matrix of distinct thickness in the telencephalon.
This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells.
, intermediate filament protein