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NXPH1 is a member of the neurexophilin family and encodes a secreted protein with a variable N-terminal domain, a highly conserved, N-glycosylated central domain, a short linker region, and a cysteine-rich C-terminal domain.
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Zebrafish nxph1 is expressed dynamically in various clusters of post-mitotic neurons and in glia in the central nervous system.
Nxph1 plays an instructive role in synaptic short-term plasticity and the configuration with GABA receptors.
results demonstrate the presence and function of a regulated signaling axis in hematopoiesis centered on NRXN1alpha and its modulation by DAG1 and NXPH1
Study on the expression of NXPH1 in the develo (show NRXN1 ELISA Kits)ping and adult olfactory bulb
identification of SNPs within the IQCJ, NXPH1, PHF17 and MYB (show MYB ELISA Kits) genes partly explaining the large interindividual variability observed in plasma triglyceride levels in response to an n-3 fatty acid supplementation
A genome-wide association study (GWAS) identified loci associated with the plasma triglyceride (TG) response to omega-3 fatty acid (FA) supplementation in IQCJ, NXPH1, PHF17 and MYB (show MYB ELISA Kits).
The role of NXPH1 in in paranoid schizophrenia development in Russians.
Rs2349775 (NXPH1) and rs17837965 (CDC42 (show CDC42 ELISA Kits)) were associated with diarrhoea and constipation predominant irritable bowel syndrome, respectively, in two independent cohorts.
Data indicate that median methylation levels of BCAN (show BCAN ELISA Kits), HOXD1, KCTD8, KLF11 (show KLF11 ELISA Kits), NXPH1, POU4F1 (show POU4F1 ELISA Kits), SIM1, and TCF7L1 (show TCF3 ELISA Kits) were >/=30% higher than in normal samples, representing potential biomarkers for tumor diagnosis.
Data indicate taht candidate genes ACTB, BZW, OCM, MACC1, NXPH1, PRPS1L1, RAC1 and RPA3, which lie within the DFNB90 region, were sequenced and no potentially causal variants were identified.
In rat, neurexophilin 1 forms a very tight complex with neurexin I alpha (show NRXN1 ELISA Kits).
In rat, the secreted ligand for alpha-neurexin (show NRXN1 ELISA Kits), neurexophilin 1, is expressed in the postnatal olfactory bulb.
This gene is a member of the neurexophilin family and encodes a secreted protein with a variable N-terminal domain, a highly conserved, N-glycosylated central domain, a short linker region, and a cysteine-rich C-terminal domain. This protein forms a very tight complex with alpha neurexins, a group of proteins that promote adhesion between dendrites and axons.
, neurexophilin 1