anti-Neurogenin 3 (NEUROG3) Antibodies

The protein encoded by NEUROG3 is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. Additionally we are shipping Neurogenin 3 Proteins (9) and Neurogenin 3 Kits (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NEUROG3 50674 Q9Y4Z2
NEUROG3 11925 P70661
NEUROG3 60329  
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Top anti-Neurogenin 3 Antibodies at antibodies-online.com

Showing 10 out of 110 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Neurog3 Antibody Titration: 1.0 ug/ml Positive Control: Mouse Pancreas 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC (p), WB The Neurogenin3 N-term polyclonal antibody (ABIN388770) is used in Western blot to detect Neurogenin3 in mouse liver tissue lysate. Neurogenin3 Antibody (C54) (ABIN388770) western blot analysis in NCI-H460 cell line lysates (35 µg/lane).This demonstrates the Neurogenin3 antibody detected the Neurogenin3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-NEUROG3 / NGN3 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100. 50 μL Log in to see 11 to 14 Days
$727.83
Details
Human Mouse Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: Neurogenin-3 Antibody (3B5) [NBP1-47878] - Neurogenin3 Immunofluorescent staining of HeLa cells transiently transfected by pCMV6-ENTRY Neurogenin-3. Immunohistochemistry-Paraffin: Neurogenin-3 Antibody (3B5) [NBP1-47878] - Staining of paraffin-embedded Human lymph node tissue using anti-Neurogenin-3 mouse monoclonal antibody. 0.1 mL Log in to see 8 to 11 Days
$587.60
Details
Human Mouse Un-conjugated WB 100 μL Log in to see 11 to 14 Days
$507.83
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western blot analysis of extracts of mouse livertissue lysate, using NEUROG3 antibody.   The lane on the left is treated with the antigen-specific peptide. ABIN6277336 at 1/100 staining Mouse heart tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse small intestine labeled with Anti-NGN3/Neurogenin 3 Polyclonal Antibody, Unconjugated (ABIN729868) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$329.45
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg Log in to see 13 to 16 Days
$350.00
Details
Human Mouse Un-conjugated ELISA, WB 100 μL Log in to see 11 to 14 Days
$478.50
Details

Top referenced anti-Neurogenin 3 Antibodies

  1. Human Monoclonal Neurogenin 3 Primary Antibody for ELISA, WB - ABIN966645 : Gradwohl, Dierich, LeMeur, Guillemot: neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. in Proceedings of the National Academy of Sciences of the United States of America 2000 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal Neurogenin 3 Primary Antibody for IF (p), IHC (p) - ABIN729868 : Jian, Mao, Xu, Li, Wang, Luo, Zhou, He, Wang, Zhang: Generation of insulin-producing cells from C3H10T1/2 mesenchymal progenitor cells. in Gene 2015 (PubMed)

More Antibodies against Neurogenin 3 Interaction Partners

Xenopus laevis Neurogenin 3 (NEUROG3) interaction partners

  1. These results provide new detail regarding the Ngn3 transcriptional network operating in endocrine progenitor cells to specify a beta cell phenotype

Human Neurogenin 3 (NEUROG3) interaction partners

  1. novel homozygous nonsense mutation (p.Q4*) as the genetic cause of neonatal diabetes mellitus and severe malabsorptive diarrhea in 2 cousins

  2. PDX1, Neurogenin-3, and MAFA are critical transcription regulators for beta cell development and regeneration. (Review)

  3. Sox9 and Ngn3, key transcription factors associated with pancreatic development.

  4. This reviews the expression and function of NEUROG3 in both mouse and human pancreatic development. [Review Article]

  5. Neurogenin3 controls its ability to promote pancreatic endocrine differentiation and to maintain beta cell function in the presence of pro-proliferation cues

  6. Phosphorylation of NEUROG3 links endocrine differentiation to the cell cycle in pancreatic progenitors

  7. Collectively, our results demonstrate that the STAT3(K392R) mutation causes premature endocrine differentiation through direct induction of NEUROG3 expression.

  8. inflammatory cytokine insults stimulate epithelial-to-mesenchymal transition (EMT) as well as the endocrine program in human pancreatic ductal cells via STAT3-dependent NGN3 activation.

  9. ChIP experiments confirmed that Pdx1 activates the expression of the downstream transcription factors, Ngn3 and Pax6, by combined with the promoter regions of insulin (Insulin-P), Ngn3 (Ngn3-P), and Pax6 (Pax6-P).

  10. NGN3 expression in the adult human exocrine pancreas marks a dedifferentiating cell population.

  11. conclude that NEUROG3 is essential for endocrine pancreas development in humans and that as little as 10% NEUROG3 is sufficient for formation of pancreatic endocrine cells

  12. NEUROG3 deficiency produces a rare clinical syndrome characterised by severe malabsorptive diarrhoea from early life and mild diabetes with a variable age of onset.

  13. Activation of the developmental pathway neurogenin-3/microRNA-7a regulates cholangiocyte proliferation in response to injury.

  14. The expression of transcription factor Ngn3 and pancreatic mesenchymal microenvironment are important and necessary to promote pancreatic progenitors differentiated to islet cells regardless of pancreatic development or islets regeneration.

  15. Recessively inherited NEUROG-3 mutations were originally identified in three patients with unexplained congenital malabsorptive diarrhea and an absence of EC.

  16. Prospectively isolated NGN3-expressing progenitors from human embryonic stem cells give rise to pancreatic endocrine cells.

  17. Data indicate associations of SNPs in eight loci CXCR4, HHEX, FOXA2, NGN3, TCF7L2, FLJ39370 (C4orf32), LOC646279 (RPL21P7) and THADA with body mass index (BMI) and weight.

  18. Ngn3-mediated pancreatic duct-to-endocrine cell reprogramming was measured employing genome wide mRNA profiling.

  19. CCAR1 is a novel partner of Ngn3 in mediating endocrine differentiation.

  20. The variants in HNFA and NEUROG3 indicate a strong predisposition of normal-weight/lean subjects to T2D in North Indians.

Mouse (Murine) Neurogenin 3 (NEUROG3) interaction partners

  1. Transgenic mice study findings suggest that pancreatic ductal cells could represent a renewable source of new beta-like cells and that strategies aiming at controlling the expression of Neurog3, or of its molecular targets/co-factors, may pave new avenues for the improved treatments of diabetes.

  2. ROCK-nmMyoII activity, Neurog3 gene-dose and Notch signaling integrate endocrine fate allocation with epithelial plexus growth and morphogenesis, representing a feedback control circuit that coordinates morphogenesis with lineage diversification in the endocrine-birth niche.

  3. Dorsal pancreas dysgenesis and ectopic pancreas is Neurog3 dependent

  4. Our data show that chemical inhibition of the H3K27me3 demethylases Jmjd3/Utx blunts Neurogenin3-dependent gene activation in vitro. Conversely, inhibition of the H3K27me3 methyltransferase Ezh2 enhances both the transactivation ability of Neurogenin3 in cultured cells and the formation of insulin-producing cells during directed differentiation from pluripotent cells

  5. This reviews the expression and function of NEUROG3 in both mouse and human pancreatic development. [Review Article]

  6. Data suggest that hepatocytes can be reprogrammed into insulin-producing cells in vivo by transfection of neurogenin-3, Pdx1, and MafA genes using non-viral hydrodynamics injection; this procedure was used in treatment of streptozotocin diabetes; fasting blood glucose was reduced to normal. (Pdx1 = pancreatic and duodenal homeobox 1; MafA = v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A)

  7. Neurogenin3 controls its ability to promote pancreatic endocrine differentiation and to maintain beta cell function in the presence of pro-proliferation cues

  8. Phosphorylation of NEUROG3 links endocrine differentiation to the cell cycle in pancreatic progenitors

  9. limiting Neurog3 expression dramatically increased the proportional representation of Sox9(+) Neurog3(TA.LO) progenitors, with a doubling of its mitotic index relative to normal Neurog3 expression, suggesting that low Neurog3 expression is a defining feature of this cycling endocrine-biased state

  10. inflammatory cytokine insults stimulate epithelial-to-mesenchymal transition (EMT) as well as the endocrine program in human pancreatic ductal cells via STAT3-dependent NGN3 activation.

  11. Duplication of pre-existing beta-cells is not the sole source of new beta-cells during pregnancy; Ngn3 may be involved in this process.

  12. data demonstrate that HIF1-alpha negatively controls beta cell differentiation in vivo by regulating NGN3 expression, and that this effect is mediated by signals from blood vessels.

  13. Data indicate that all neurogenin 3 (Neurog3)-tuberous sclerosis complex 1 (Tsc1)-/- mice developed notable adenocarcinoma-like lesions in pancreas starting from the age of 100 days old.

  14. Activation of the developmental pathway neurogenin-3/microRNA-7a regulates cholangiocyte proliferation in response to injury.

  15. Hnf1b plays a crucial role in the regulatory networks that control pancreatic MPC expansion, acinar cell identity, duct morphogenesis and generation of endocrine precursors.

  16. The role of neurogenin 3 and PD-L1 in the genesis of neo-islets in NOD mice is reported.

  17. the prophylactic administration of Ad-hNgn3 before diabetic induction protected mice from developing hyperglycemia

  18. Neurog3 establishes the posterior boundary of the serotonergic system by actively suppressing serotonergic specification in the spinal cord.

  19. Insm1 works to promote endocrine cell differentiation in a pathway that involves Neurog3 and Ripply3

  20. three transcription factors, PDX1, NGN3 and MAFA, are very important in pancreatic development. Overexpression of these three factors can reprogram both pancreatic exocrine and SOX9-positive cells of the liver into cells resembling pancreatic beta cells

Zebrafish Neurogenin 3 (NEUROG3) interaction partners

  1. The control of endocrine cell fate is instead fulfilled by two basic helix-loop-helix factors, Ascl1b and Neurod1 and NEUROG3 is not the unique pancreatic endocrine cell fate determinant in vertebrates.

  2. Nkx2.2 coordinately activates NeuroD1 with Ngn3 in the endocrine progenitor cell and plays a role in the maintenance of NeuroD1 expression to regulate beta cell function in the mature islet.

Neurogenin 3 (NEUROG3) Antigen Profile

Protein Summary

The protein encoded by this gene is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4).

Gene names and symbols associated with anti-Neurogenin 3 (NEUROG3) Antibodies

  • neurogenin 3 (NEUROG3) antibody
  • neurogenin 3 (neurog3) antibody
  • neurogenin 3 S homeolog (neurog3.S) antibody
  • neurogenin-3 (Tsp_02556) antibody
  • neurogenin 3 (Neurog3) antibody
  • atoh4 antibody
  • Atoh5 antibody
  • bHLHa7 antibody
  • Math4B antibody
  • neurog3 antibody
  • NGN-3 antibody
  • ngn2 antibody
  • Ngn3 antibody
  • ngn3a antibody
  • Relax antibody

Protein level used designations for anti-Neurogenin 3 (NEUROG3) Antibodies

neurogenin 3 , neurogenin-3 , class A basic helix-loop-helix protein 7 , protein atonal homolog 5 , NGN-3 , Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B) , atonal homolog 5 , helix-loop-helix protein mATH-4B , transcriptional regulator, Relax , Zath4b , atonal homolog 4

GENE ID SPECIES
711583 Macaca mulatta
748874 Pan troglodytes
100038294 Xenopus (Silurana) tropicalis
100188927 Xenopus laevis
100461771 Pongo abelii
10898849 Trichinella spiralis
50674 Homo sapiens
11925 Mus musculus
60329 Rattus norvegicus
489022 Canis lupus familiaris
540130 Bos taurus
780450 Ovis aries
114411 Danio rerio
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