anti-Neuropeptide S (NPS) Antibodies

Modulates arousal and anxiety. Additionally we are shipping NPS Kits (30) and NPS Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NPS 594857 P0C0P6
NPS 100043254 P0C0P8
NPS 100360071 P0C0P7
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Top anti-NPS Antibodies at

Showing 10 out of 103 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Guinea Pig Rabbit Un-conjugated WB 100 μL Log in to see 11 to 14 Days
Human Rabbit Un-conjugated ELISA, IHC, WB Western blot analysis NPS using HepG2 whole cell lysates ABIN6279614 at 1/100 staining Mouse kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Log in to see 11 to 12 Days
Mouse Rabbit Un-conjugated WB Western blot analysis of Neuropeptide S using anti-Neuropeptide S antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: rat brain tissue lysates, Lane 2: mouse brain tissue lysates.  After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-Neuropeptide S antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for Neuropeptide S at approximately 19KD. The expected band size for Neuropeptide S is at 10KD. 100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated ICC, IHC, WB DAB staining on IHC-P; Samples: Human Liver Tissue 100 μg Log in to see 15 to 18 Days
Mouse Rabbit Un-conjugated ICC, IHC, WB DAB staining on IHC-P;;Samples: Mouse Kidney Tissue 100 μg Log in to see 13 to 16 Days
Rat Rabbit Un-conjugated ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin-embedded Brain tissue 100 μg Log in to see 13 to 16 Days
Rat Rabbit Un-conjugated WB   100 μL Log in to see 11 to 14 Days
Mouse Rabbit Un-conjugated IHC   100 μL Log in to see 11 to 14 Days
Human Rabbit Un-conjugated IHC   100 μL Log in to see 11 to 14 Days

More Antibodies against NPS Interaction Partners

Human Neuropeptide S (NPS) interaction partners

  1. SNPs modify asthma risk

  2. A SNP within the neuropeptide s gene is associated with decreased bioactivity.

  3. NPS is able to stimulate human monocyte chemotaxis and that this effect is entirely due to selective NPSR activation.

  4. The available information regarding NPS and its receptor and the biological actions modulated by the NPS-NPSR system, is summarized.

  5. NPS-NPSR1 signaling is likely involved in anxiety

  6. NPS has a novel role in the stimulation of the hypothalamo-pituitary-adrenal axis

  7. the C-terminal region of neuropeptide S maintains importance for in vivo activity

  8. the key residues of NPS involved in NPSR activation and suggest a molecular basis for the functional effects of the N107I mutation and for its putative pathophysiological link with asthma

  9. Because remodeling of airway epithelium is a feature of chronic asthma, the up-regulation of MMP10 and TIMP3 by NPS-NPSR1 signaling may be of relevance in the pathogenesis of asthma.

  10. NPS acts as a novel modulator of arousal and anxiety-related behaviours by promoting a unique pattern of effects: stimulation associated with anxiolysis.

Mouse (Murine) Neuropeptide S (NPS) interaction partners

  1. Study showed that the actions of neuropeptide S influenced the excitability of dorsal raphe and laterodorsal tegmentum neurons, which could play a role in the anxiolytic and arousal-promoting effects of this peptide.

  2. NPS-/- mice display significant deficits in exploratory activity, long-term memory and arousal.

  3. Findings demonstrate that neuropeptide S, via selective activation of the neurons bearing neuropeptide S receptor in the subiculum complex, ameliorates olfactory spatial memory impairment induced by scopolamine and MK801 in mice.

  4. these results indicate that NPS-NPSR system may regulate locomotion together with the CRF1 system in SN.

  5. Study demonstrated that NPS produces anti-aggressive effects in mice through the selective activation of NPSR and that the endogenous NPS/NPSR system can exert a role in the control of aggressiveness levels under the present experimental conditions

  6. These data provide evidence for a direct interaction between the corticotropin-releasing factor and the NPS system and thereby extend previous observations of NPS-modulated stress responsiveness towards a mechanistic level.

  7. Neuropeptide S knock-out mice display deficits in inhibitory avoidance memory indicating involvement in central noradrenergic systems.

  8. Results describe the neuroanatomical, molecular, and functional aspects of neuropeptide S-producing neurons in the mouse brain.

  9. These data demonstrate that the distribution pattern of the central neuropeptide S system is only partially conserved between mice and rats.

  10. results demonstrate that neuropeptide S and NPSR1 regulate respiratory function through a central nervous system-mediated pathway

  11. Data suggest that lithium evokes antagonistic effects on the mediation of hyperlocomotion and protection against lipid peroxidation induced by neuropeptide S.

  12. analysis of a neuropeptide S responsive circuitry shaping amygdala activity via the endopiriform nucleus

  13. NPS facilitates spatial memory and mitigates MK801-induced spatial memory impairment in mice.

NPS Antigen Profile

Protein Summary

Modulates arousal and anxiety. May play an important anorexigenic role. Binds to its receptor NPSR1 with nanomolar affinity to increase intracellular calcium concentrations (By similarity).

Gene names and symbols associated with anti-Neuropeptide S (NPS) Antibodies

  • neuropeptide S (NPS) antibody
  • neuropeptide S (Nps) antibody
  • ENSMUSG00000073804 antibody

Protein level used designations for anti-Neuropeptide S (NPS) Antibodies

prepro-neuropeptide S , neuropeptide S

594857 Homo sapiens
100043254 Mus musculus
100188981 Sus scrofa
100302434 Oryctolagus cuniculus
100360071 Rattus norvegicus
100297291 Bos taurus
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