Neurotensin Receptor 1 (High Affinity) Proteins (NTSR1)

Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. Additionally we are shipping NTSR1 Antibodies (90) and NTSR1 Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat NTSR1 NTSR1 366274 P20789
NTSR1 18216 O88319
NTSR1 4923 P30989
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Top NTSR1 Proteins at

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
Insect Cells Human rho-1D4 tag,His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 40 Days
Wheat germ Human Un-conjugated   10 μg Log in to see 11 to 12 Days
Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 11 to 18 Days
Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days

NTSR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,

Human , ,

More Proteins for Neurotensin Receptor 1 (High Affinity) (NTSR1) Interaction Partners

Mouse (Murine) Neurotensin Receptor 1 (High Affinity) (NTSR1) interaction partners

  1. The weight loss behaviors are mediated by distinct signaling pathways: Nts (show NTS Proteins) action via NtsR1 is essential for the anorectic effect of the lateral hypothalamic Nts (show NTS Proteins) circuit, but not for regulation of locomotor or drinking behavior.

  2. Data demonstrate that the NTR1 can modulate the methamphetamine-induced striatal neuronal apoptosis independent of body temperature regulation. Possible mechanisms of NTR1 modulating methamphetamine-induced apoptosis include the regulation of dopamine and glutamate (show GRIN1 Proteins) neurotransmission in the striatum.

  3. The roles of neurotensin and its receptor NTR-1 on sperm capacitation and acrosome reaction in mice are reported.

  4. sleep traits and a relationship between Ntsr1 and anxiety and despair behaviors in knockout mice

  5. Data show that NTS1 (show NTS Proteins)(-/-) mouse is an animal model of schizophrenia, particularly for the dysfunction of the prefrontal cortex.

  6. Ntsr1 knockout mice showed a higher freezing rate than wild type mice at both first and second exposures under the condition where a relatively weak unconditioned stimulus (footshock)

  7. Ntsr1 receptor subtype is necessary for normal dopaminergic function.

  8. These findings support the role for Ntsr1 in the mediation of the metabolic effect of xenin (show COPA Proteins) as well as neurotensin (show NTS Proteins).

  9. Neurotensin (show NTS Proteins) type 1 receptor does not play a role in NT-induced analgesia, but that it is clearly implicated in thermal and feeding regulation, weight control, and NT-induced hypolocomotion.

  10. constant activation of NT1 receptor generates an oncogenic regulation

Human Neurotensin Receptor 1 (High Affinity) (NTSR1) interaction partners

  1. This study strongly suggests that the addition of NTSR1 inhibitor in combination with platinum salt-based therapy will improve the response to the drug.

  2. Our findings identify promoter methylation as an important process regulating the differential expression or silencing of NTSR1/2 in Colorectal cancer (CRC (show CALR Proteins)) cells. Moreover, inhibition of NTSR1 repressed tumorigenic effects in CRC (show CALR Proteins) cells, suggesting that NTSR1 may be used as a therapeutic target for CRC (show CALR Proteins).

  3. inducing exogenous neurotensin stimulation and enhancing NTR1 expression promoted tumor invasion rather than proliferation by accelerating epithelial-to-mesenchymal transition in hepatocellular carcinoma cells.

  4. High NTR1 expression is associated with pancreatic ductal adenocarcinoma.

  5. Data suggest that small molecule ligand binding to neurotensin receptor 1 (NTSR1) could facilitate the structure-based design of non-peptide ligands for the evaluation of the pharmacological potential of NTSR1 in neurological disorders and cancer.

  6. The results reveal a positive feedback loop between NTS (show NTS Proteins)/NTSR1 and Wnt (show WNT2 Proteins)/beta-Catenin (show CTNNB1 Proteins) signaling in glioblastoma cells that might be important for tumor development and provide potential therapeutic targets for glioblastoma.

  7. NTSR1 overexpression is a poor prognostic factor in endometrial cancer, highlighting the contribution of NTS (show NTS Proteins) in endometrial cancer progression

  8. Heterodimerization of the kappa opioid receptor (show OPRK1 Proteins) and neurotensin receptor 1 contributes to a novel beta-arrestin-2 (show ARRB2 Proteins)-signaling pathway.

  9. Silencing of miR-133alpha or overexpression of aftiphilin attenuated NTR1 trafficking to plasma membrane in human colonocytes.

  10. Neurotensin (show NTS Proteins) receptor-targeted oncolytic adenovirus co-expressing decorin (show DCN Proteins) and Wnt (show WNT2 Proteins) antagonist useful for systemic treatment of NTR-overexpressing pancreatic cancer.

NTSR1 Protein Profile

Protein Summary

Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion.

Gene names and symbols associated with NTSR1

  • neurotensin receptor 1 (NTSR1)
  • neurotensin receptor 1 (high affinity) (NTSR1)
  • neurotensin receptor 1 (Ntsr1)
  • NT-1R protein
  • NTR protein
  • NTR-1 protein
  • NTR1 protein
  • Ntsr protein
  • NTSR1 protein

Protein level used designations for NTSR1

neurotensin receptor type 1 , neurotensin receptor 1 (high affinity) , neurotensin receptor type 1-like , NT-R-1 , NTR1 , NTRH , high-affinity levocabastine-insensitive neurotensin receptor

428149 Gallus gallus
458392 Pan troglodytes
485963 Canis lupus familiaris
528416 Bos taurus
698936 Macaca mulatta
100394234 Callithrix jacchus
100479759 Ailuropoda melanoleuca
366274 Rattus norvegicus
18216 Mus musculus
4923 Homo sapiens
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