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The protein encoded by NTM is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. Additionally we are shipping Neurotrimin Antibodies (48) and Neurotrimin Proteins (12) and many more products for this protein.
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NTM is not a susceptibility gene for autism spectrum disorders.
Both the AFF3 and NTM triglyceride associations were replicated among Multi-ethnic Study of Atherosclerosis study participants (P = 1.00 x 10(-7) and 8.00 x 10(-5), respectively).
The generation and cardiac phenotype of single and double heterozygous gene-targeted OPCML and Neurotrimin knockout mice.
A translocation breaks intron 1 of a splicing isoform of Neurotrimin at 11q25 in a family with intracranial and thoracic aortic aneurysm.
A quantitative analysis of central corneal thickness and a subsequent analysis of primary open-angle glaucoma (POAG), SNPs in two cell adhesion molecules, NTM and CNTNAP4, were identified and may increase POAG susceptibility in a subset of cases.
The finding of this study provided evidence that NTM at 11q25 chromosome regions affecting IQ.
Human neurotrimin is expressed on the surface of CHO cells and could strengthen their aggregation.
NTM shows close linkage to OPCML on chromosome 11q25.
Phenotyping neurons derived from the hippocampi of Lsamp(-/-), Ntm(-/-) and Lsamp(-/-)Ntm(-/-) mice was performed in parallel with behavioral testing. While the anatomy of mutant brains revealed no gross changes, the Ntm(-/-) hippocampal neurons exhibited premature sprouting of neurites and manifested accelerated neurite elongation and branching.
This study demonstrated that in neurotrimin knockout mice showed a deficit in emotional learning in the active avoidance task and decreased sensitivity to the locomotor stimulating effect of amphetamine.
This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules. The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism. This gene is closely linked to a related family member, opioid binding protein/cell adhesion molecule-like (OPCML), on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene.
IgLON family member 2
, protein CEPU-1
, CEPU-Se alpha 1 isoform
, CEPU-Se alpha 2 isoform
, IgLON family protein
, neural secreted glycoprotein