Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

anti-NPC1 Antibodies

NPC1 encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain.

50 results:

anti-NPC1 antibody (Niemann-Pick Disease, Type C1) (AA 34-174) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivity: Human IHC, ELISA, WB Host: Mouse Monoclonal 8D10B6 unconjugated
Pubmed 2
Catalog No. ABIN1724876
$448.80
Plus shipping costs $45.00
0.1 mg
local_shipping Shipping to: United States
Delivery in 3 to 4 Business Days

anti-NPC1 antibody (Niemann-Pick Disease, Type C1) (AA 34-174) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivity: Human FACS, IHC, ELISA, WB Host: Mouse Monoclonal unconjugated
Catalog No. ABIN1845969
$478.68
Plus shipping costs $45.00
100 μg
local_shipping Shipping to: United States
Delivery in 11 to 16 Business Days

anti-NPC1 antibody (Niemann-Pick Disease, Type C1) (AA 591-620) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivity: Human IF, IHC, ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3031998
$493.63
Plus shipping costs $45.00
0.4 mL (More quantities available)
local_shipping Shipping to: United States
Delivery in 2 to 3 Business Days

anti-NPC1 antibody (Niemann-Pick Disease, Type C1) (C-Term) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivity: Human ELISA, FM, IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6655360
$379.00
Plus shipping costs $45.00 and $24.00 dry ice
100 μg
local_shipping Shipping to: United States
Delivery in 1 to 2 Business Days

anti-NPC1 antibody (Niemann-Pick Disease, Type C1) (AA 151-250) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivity: Human ELISA, WB Host: Mouse Monoclonal 4H2 unconjugated
Catalog No. ABIN562034
$440.00
Plus shipping costs $45.00
100 μg
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

anti-NPC1 antibody (Niemann-Pick Disease, Type C1) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivity: Human IF, IHC, IHC (p), IP, WB Host: Mouse Monoclonal unconjugated
Catalog No. ABIN462125
$727.83
Plus shipping costs $45.00
50 μg
local_shipping Shipping to: United States
Delivery in 11 to 14 Business Days

anti-NPC1 antibody (Niemann-Pick Disease, Type C1) (C-Term) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivity: Human EIA, IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500383
$511.50
Plus shipping costs $45.00
0.1 mg
local_shipping Shipping to: United States
Delivery in 6 to 8 Business Days

anti-NPC1 antibody (Niemann-Pick Disease, Type C1) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 IEM, IF, IHC, IP, WB Host: Rabbit Polyclonal unconjugated
Pubmed 3
Catalog No. ABIN540364
$542.86
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

anti-NPC1 antibody (Niemann-Pick Disease, Type C1) (C-Term) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivity: Human, Mouse ELISA, IHC, IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN959667
$616.00
Plus shipping costs $45.00
50 μg
local_shipping Shipping to: United States
Delivery in 11 to 14 Business Days

anti-NPC1 antibody (Niemann-Pick Disease, Type C1) (Internal Region) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivity: Human ELISA, WB Host: Goat Polyclonal unconjugated
Catalog No. ABIN1590132
$481.84
Plus shipping costs $45.00
100 μg
local_shipping Shipping to: United States
Delivery in 6 to 7 Business Days
  • Type Primary
    • Primary
  • Target Niemann-Pick Disease, Type C1 (NPC1)
    • Niemann-Pick Disease, Type C1 (NPC1)
    • Histone 3 (H3)
    • Tumor Protein P53 (TP53)
    • Epidermal Growth Factor Receptor (EGFR)
    • Mast/stem Cell Growth Factor Receptor (KIT)
    • Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
    • CD4 Molecule (CD4)
    • tau Protein
    • Tumor Necrosis Factor alpha (TNF)
    • Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2)
    • V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)
    • Interferon gamma (IFNG)
    • Estrogen Receptor 1 (ESR1)
    • Albumin (ALB)
    • Nuclear Factor-KB P65 (NFkBP65)
    • BCL2-Associated Agonist of Cell Death (BAD)
    • V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
    • B-Cell CLL/lymphoma 2 (BCL2)
    • Tuberous Sclerosis 2 (TSC2)
    • CD44
    • Amyloid beta (A4) Precursor Protein (APP)
    • CD19 Molecule (CD19)
    • CD8a Molecule (CD8A)
    • Hemagglutinin (HA)
    • Platelet/endothelial Cell Adhesion Molecule (PECAM1)
    • CD3e Molecule, epsilon (CD3-TCR Complex) (CD3E)
    • Myc Proto-Oncogene protein (MYC)
    • Integrin alpha M (ITGAM)
    • CD8
    • Histone H4
    • Interleukin 6 (IL6)
    • Vimentin (VIM)
    • Jun Proto-Oncogene (JUN)
    • Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1)
    • Epithelial Cell Adhesion Molecule (EPCAM)
    • C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
    • Interleukin 2 Receptor, alpha (IL2RA)
    • CD5 Molecule (CD5)
    • Interleukin 2 (IL2)
    • CD3
    • PTK2 Protein tyrosine Kinase 2 (PTK2)
    • Synuclein, alpha (SNCA)
    • Glial Fibrillary Acidic Protein (GFAP)
    • Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1)
    • CD14
    • Androgen Receptor (AR)
    • Mucin 1, Cell Surface Associated (MUC1)
    • Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR)
    • CD34
    • Cyclin-Dependent Kinase 1 (CDK1)
    • Activating Transcription Factor 2 (ATF2)
  • Application
    • ELISA
    • Western Blotting (WB)
    • Immunohistochemistry (IHC)
    • Immunofluorescence (IF)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunocytochemistry (ICC)
    • Flow Cytometry (FACS)
    • Immunoprecipitation (IP)
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Enzyme Immunoassay (EIA)
    • Fluorescence Microscopy (FM)
    • Immunoelectron Microscopy (IEM)
    • Immunofluorescence (Cultured Cells) (IF (cc))
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Images available
  • Host
    • Rabbit
    • Goat
    • Mouse
  • Clonality
    • Polyclonal
    • Monoclonal
  • Clone
    • 14i194
    • 1B12
    • 4H2
    • 8D10B6
  • Binding Specificity
    • Internal Region
    • AA 590-620
    • Center
    • AA 591-620
    • C-Term
    • AA 23-269
    • AA 34-174
    • AA 1022-1278
    • AA 151-250
    • AA 372-622
  • Conjugate
    • Un-conjugated
    • Biotin
    • FITC
    • APC
    • Alkaline Phosphatase (AP)
    • HRP
    • PE
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
  • Isotype
    • IgG
    • IgG1
    • Ig Fraction
    • IgG2a kappa
  • Format
    • Liquid
    • Lyophilized

NPC1 Antigen Profile

Protein Summary

This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.

Gene names and symbols associated with NPC1

  • NPC intracellular cholesterol transporter 1 (NPC1) antibody
  • Niemann-Pick disease, type C1 (npc1) antibody
  • Niemann-Pick C1 protein (LOC579887) antibody
  • NPC intracellular cholesterol transporter 1 (Npc1) antibody
  • A430089E03Rik antibody
  • C85354 antibody
  • Cdig2 antibody
  • D18Ertd139e antibody
  • D18Ertd723e antibody
  • im:7149020 antibody
  • lcsd antibody
  • nmf164 antibody
  • NPC antibody
  • spm antibody
  • wu:fb53a12 antibody
  • wu:fc29a12 antibody

Protein level used designations for NPC1

Niemann-Pick C1 protein , Niemann-Pick type C1 disease protein , Nasopharyngeal carcinoma 1 , Niemann-Pick C1 , Niemann-Pick disease, type C1 , sphingomyelinosis , Niemann-Pick C disease protein

GENE ID SPECIES
403698 Canis lupus familiaris
455338 Pan troglodytes
493693 Felis catus
553330 Danio rerio
579887 Strongylocentrotus purpuratus
100008746 Oryctolagus cuniculus
18145 Mus musculus
4864 Homo sapiens
397591 Sus scrofa
421076 Gallus gallus
266732 Rattus norvegicus
100718604 Cavia porcellus

Did you look for something else?

You are here: