anti-NPC1 Antibodies

NPC1 encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain.

Data Quality
  • 2
  • 17
Type
  • 68
    Primary antibodies
Antigen
  • 68
Reactivity
  • 60
  • 17
  • 8
Application
  • 48
  • 46
  • 34
  • 18
  • 11
Detection Method
  • 3
Host
  • 51
  • 9
  • 8
Clonality
  • 56
  • 12
Clone
  • 3
  • 2
  • 2
  • 1
  • 1
Binding Specificity
  • 15
  • 12
  • 7
  • 7
  • 5
Conjugate
  • 42
  • 4
  • 4
  • 3
  • 3
Isotype
  • 36
  • 6
  • 2
  • 1
Format
  • 52
  • 1
68 Products
ReactivityHuman
Application FACS, IHC, ELISA, WB
Order details Cat. No. ABIN1845969
$464.30
100 μg
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application IF, IHC, ELISA, WB
Order details Cat. No. ABIN3031998
$452.38
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
$464.30
100 μg
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application IHC, ELISA, WB
Order details Cat. No. ABIN1724876
$430.10
0.1 mg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityHuman
Application IF, IHC, IHC (p), IP, WB
Order details Cat. No. ABIN462125
$727.83
50 μg
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN1590132
$429.87
100 μg
Plus shipping costs $45.00
Delivery in 6 to 7 Business Days
ReactivityHuman
Application IHC, ELISA, WB
Order details Cat. No. ABIN1030549
$370.00
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application ELISA, IHC, WB
Order details Cat. No. ABIN5584666
$460.00
100 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IHC, ELISA
Order details Cat. No. ABIN2433479
$493.90
Plus shipping costs $45.00
Delivery in 12 to 14 Business Days
ReactivityHuman
Application EIA, IHC (p), WB
Order details Cat. No. ABIN500383
$500.50
0.1 mg
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
Reactivity
Application IEM, IF, IHC, IP, WB
Order details Cat. No. ABIN540364
$542.86
100 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman, Mouse (Murine)
Application ELISA, IHC, IHC (p), WB
Order details Cat. No. ABIN959667
$616.00
50 μg
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
ReactivityHuman
Application IHC (p), IHC, ELISA, WB
Order details Cat. No. ABIN1737464
$670.26
50 μg
Plus shipping costs $45.00
Delivery in 12 to 14 Business Days
ReactivityMouse (Murine)
Application ELISA
Order details Cat. No. ABIN570865
$278.78
100 μg
Plus shipping costs $45.00
Delivery in 6 to 7 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN2147755
$483.57
50 μL
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application ELISA, WB
Order details Cat. No. ABIN5693129
$240.00
100 μg
Plus shipping costs $45.00
Delivery in 4 to 6 Business Days
ReactivityHuman
Application ELISA, FM, IHC, WB
Order details Cat. No. ABIN6655360
$405.90
100 μg
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 1 to 2 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN562034
$440.00
100 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application IHC (p)
Order details Cat. No. ABIN5584667
$577.33
100 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application ELISA
Order details Cat. No. ABIN6923952
ISO
$206.25
Plus shipping costs $45.00
Delivery in 14 to 16 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IF (p), IHC (p), WB
Order details Cat. No. ABIN872416
$327.80
100 μL
Plus shipping costs $45.00
Delivery in 3 to 7 Business Days
$394.90
100 μL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application FACS, IF (cc), IF (p), IHC (p), WB
Order details Cat. No. ABIN6949575
$413.49
100 μL
Plus shipping costs $45.00
Delivery in 14 to 21 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application FACS, IF (cc), IF (p), IHC (p), WB
Order details Cat. No. ABIN6947619
$413.49
100 μL
Plus shipping costs $45.00
Delivery in 14 to 21 Business Days
$416.90
100 μL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
$416.90
100 μL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
$416.90
100 μL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
$416.90
100 μL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
$416.90
100 μL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application FACS, IF (cc), IF (p), IHC (p), WB
Order details Cat. No. ABIN6944307
$426.80
100 μL
Plus shipping costs $45.00
Delivery in 14 to 21 Business Days
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NPC1 Antigen Profile

Protein Summary

This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.

Gene names and symbols associated with NPC1

  • NPC intracellular cholesterol transporter 1 (NPC1) antibody
  • Niemann-Pick disease, type C1 (npc1) antibody
  • Niemann-Pick C1 protein (LOC579887) antibody
  • NPC intracellular cholesterol transporter 1 (Npc1) antibody
  • A430089E03Rik antibody
  • C85354 antibody
  • Cdig2 antibody
  • D18Ertd139e antibody
  • D18Ertd723e antibody
  • im:7149020 antibody
  • lcsd antibody
  • nmf164 antibody
  • NPC antibody
  • spm antibody
  • wu:fb53a12 antibody
  • wu:fc29a12 antibody

Protein level used designations for NPC1

Niemann-Pick C1 protein , Niemann-Pick type C1 disease protein , Nasopharyngeal carcinoma 1 , Niemann-Pick C1 , Niemann-Pick disease, type C1 , sphingomyelinosis , Niemann-Pick C disease protein

GENE ID SPECIES
403698 Canis lupus familiaris
455338 Pan troglodytes
493693 Felis catus
553330 Danio rerio
579887 Strongylocentrotus purpuratus
100008746 Oryctolagus cuniculus
18145 Mus musculus
4864 Homo sapiens
397591 Sus scrofa
421076 Gallus gallus
266732 Rattus norvegicus
100718604 Cavia porcellus
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