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Nischarin Antibodies

(Nischarin (NISCH))
This gene encodes a nonadrenergic imidazoline-1 receptor protein that localizes to the cytosol and anchors to the inner layer of the plasma membrane. The orthologous mouse protein has been shown to influence cytoskeletal organization and cell migration by binding to alpha-5-beta-1 integrin. In humans, this protein has been shown to bind to the adapter insulin receptor substrate 4 (IRS4) to mediate translocation of alpha-5 integrin from the cell membrane to endosomes. Expression of this protein was reduced in human breast cancers while its overexpression reduced tumor growth and metastasis\; possibly by limiting the expression of alpha-5 integrin. In human cardiac tissue, this gene was found to affect cell growth and death while in neural tissue it affected neuronal growth and differentiation. Alternative splicing results in multiple transcript variants encoding differerent isoforms. Some isoforms lack the expected C-terminal domains of a functional imidazoline receptor. [provided by RefSeq, Jan 2013].
anti-Nischarin (NISCH) (AA 1246-1346) antibody anti-Nischarin (NISCH) (AA 1246-1346) antibody anti-Nischarin (NISCH) (AA 1246-1346) antibody (ABIN1869472)

NISCH Reactivity: Human ICC, IHC, WB Host: Rabbit Polyclonal unconjugated

anti-Nischarin (NISCH) (AA 1335-1435) antibody anti-Nischarin (NISCH) (AA 1335-1435) antibody anti-Nischarin (NISCH) (AA 1335-1435) antibody (ABIN1980473)

NISCH Reactivity: Mouse ICC, IHC, WB Host: Rabbit Polyclonal unconjugated

anti-Nischarin (NISCH) (AA 1246-1345) antibody anti-Nischarin (NISCH) (AA 1246-1345) antibody anti-Nischarin (NISCH) (AA 1246-1345) antibody (ABIN524609)

NISCH Reactivity: Human ELISA, WB Host: Mouse Monoclonal 3B8 unconjugated

Nischarin Antibodies by Reactivity

Find Nischarin Antibodies for a variety of species such as anti-Human Nischarin, anti-Mouse Nischarin, anti-Rat Nischarin. The species listed below are among those available. Click on a link to go to the corresponding products.

Nischarin Antibodies by Application

Find Nischarin Antibodies validated for a specific application such as WB, ELISA, IHC, ICC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Nischarin Antibodies by Host

Find Nischarin Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

Nischarin Antibodies by Binding Specificity

Find Nischarin Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Nischarin Antibodies by Clonality

Find available monoclonal or polyclonal Nischarin Antibodies. Click on a link to go to the corresponding products.

Nischarin Antibodies by Clone

Find Nischarin Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

Popular Nischarin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC
Validations
Cat. No. ABIN7161622
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IP, WB
Validations
Cat. No. ABIN7116889
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
Cat. No. ABIN7135234
Quantity 150 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN5672022
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
Cat. No. ABIN7094392
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
Cat. No. ABIN6242733
Quantity 200 μL
Datasheet Datasheet
Reactivity Mouse
Application WB
Validations
Cat. No. ABIN2586261
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
Cat. No. ABIN2772893
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
Cat. No. ABIN2327371
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IF/ICC, IHC, IP, WB
Validations
Cat. No. ABIN6335986
Quantity 1 mL
Datasheet Datasheet

Latest Publications for our Nischarin Antibodies

Alahari, Nasrallah: "A membrane proximal region of the integrin alpha5 subunit is important for its interaction with nischarin." in: The Biochemical journal, Vol. 377, Issue Pt 2, pp. 449-57, (2004) (PubMed).

Alahari, Reddig, Juliano: "The integrin-binding protein Nischarin regulates cell migration by inhibiting PAK." in: The EMBO journal, Vol. 23, Issue 14, pp. 2777-88, (2004) (PubMed).

Juliano, Reddig, Alahari, Edin, Howe, Aplin: "Integrin regulation of cell signalling and motility." in: Biochemical Society transactions, Vol. 32, Issue Pt3, pp. 443-6, (2004) (PubMed).

Alahari: "Nischarin inhibits Rac induced migration and invasion of epithelial cells by affecting signaling cascades involving PAK." in: Experimental cell research, Vol. 288, Issue 2, pp. 415-24, (2003) (PubMed).

Alahari, Lee, Juliano: "Nischarin, a novel protein that interacts with the integrin alpha5 subunit and inhibits cell migration." in: The Journal of cell biology, Vol. 151, Issue 6, pp. 1141-54, (2001) (PubMed).

Aliases for Nischarin Antibodies

nischarin (NISCH) Antibodies
nischarin (Cyan7822_6841) Antibodies
nischarin S homeolog (nisch.S) Antibodies
nischarin (nisch) Antibodies
nischarin (Nisch) Antibodies
1200007D05Rik Antibodies
3202002H23Rik Antibodies
AW494485 Antibodies
hIRAS Antibodies
I-1 Antibodies
IR1 Antibodies
IRAS Antibodies
NISCH Antibodies
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