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NSMCE2 Proteins

E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination.

8 results:

Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2) (AA 1-247) protein (His tag) Protein

NSMCE2 Origin: Human Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3094191
$7,167.70
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 50 Business Days
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Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2) (AA 1-247) protein (His tag) Protein

NSMCE2 Origin: Mouse Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3136789
$7,167.70
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 50 Business Days
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Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2) protein (His tag) Protein

NSMCE2 Origin: Human Source: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Catalog No. ABIN2727651
$302.50
Plus shipping costs $45.00 and $24.00 dry ice
50 μg
local_shipping Shipping to: United States
Will be delivered in 11 Business Days
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Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2) (AA 1-247) protein (GST tag) Protein

NSMCE2 Origin: Human Source: Wheat germ Recombinant AP, AA, ELISA, WB
Catalog No. ABIN1313078
$414.29
Plus shipping costs $45.00 and $24.00 dry ice
10 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days
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Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2) (AA 1-238) protein (His tag) Protein

NSMCE2 Origin: Xenopus laevis Source: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1678295
$2,603.33
Plus shipping costs $45.00
1 mg
local_shipping Shipping to: United States
Delivery in 60 to 71 Business Days
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Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2) (AA 1-247) protein (His tag) Protein

NSMCE2 Origin: Rat Source: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1631717
$2,632.67
Plus shipping costs $45.00
1 mg
local_shipping Shipping to: United States
Delivery in 60 to 71 Business Days
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Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2) (AA 1-248) protein (His tag) Protein

NSMCE2 Origin: Cow Source: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1626331
$2,634.50
Plus shipping costs $45.00
1 mg
local_shipping Shipping to: United States
Delivery in 60 to 71 Business Days
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Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2) (AA 1-250) protein (His tag) Protein

NSMCE2 Origin: Schizosaccharomyces pombe Source: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1630605
$2,641.83
Plus shipping costs $45.00
1 mg
local_shipping Shipping to: United States
Delivery in 60 to 71 Business Days
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  • Type Protein
    • Protein
  • Target Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
    • Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interferon gamma (IFNG)
    • Interleukin 6 (IL6)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Interleukin 4 (IL4)
    • Thymidylate Kinase (Tmk)
    • Interleukin 1, beta (IL1B)
    • Interleukin 2 (IL2)
    • Uracil-DNA Glycosylase (UNG)
    • Growth Hormone 1 (GH1)
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Lipoyl synthase lipA
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Leptin (LEP)
    • Epidermal Growth Factor (EGF)
    • Interleukin 8 (IL8)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • Hemoglobin, alpha 1 (HBA1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • phosphatidylserine Decarboxylase (PISD)
    • Interleukin 1 alpha (IL1A)
    • Prolactin (PRL)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Albumin (ALB)
    • Interleukin 13 (IL13)
    • CD40 Ligand (CD40LG)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phosphoglucosamine Mutase (GLMM)
    • Interleukin 15 (IL15)
    • Porphobilinogen Deaminase (HEMC)
    • beta-2-Microglobulin (B2M)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Adiponectin (ADIPOQ)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Gp120
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
    • Interleukin 33 (IL33)
    • Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1)
  • Application
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Crystallization (Crys)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Protein Interaction (PI)
    • Standard (STD)
  • Reactivity
    • Human
    • Cow
    • Mouse
    • Rat
    • Schizosaccharomyces pombe
    • Xenopus laevis
  • Images available
  • Host
    • Yeast
    • Insect Cells
    • Escherichia coli (E. coli)
    • Wheat germ
  • Binding Specificity
    • AA 1-247
    • AA 1-238
    • AA 1-248
    • AA 1-250
  • Conjugate
    • Un-conjugated
    • His tag
    • GST tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid

NSMCE2 Protein Profile

Protein Summary

E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. Is not be required for the stability of the complex.The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, the shelterin complex subunits TERF1, TERF2, TINF2 and TERF2IP, and maybe the cohesin components RAD21 and STAG2. Required for recruitment of telomeres to PML nuclear bodies. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair. Required for sister chromatid cohesion during prometaphase and mitotic progression (By similarity).

Gene names and symbols associated with NSMCE2

  • NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (Nsmce2) antibody
  • NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (NSMCE2) antibody
  • NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase L homeolog (nsmce2.L) antibody
  • Smc5-6 complex non-SMC subunit 2 (nse2) antibody
  • 1110014D18Rik antibody
  • AI661537 antibody
  • C8orf36 antibody
  • MMS21 antibody
  • Non-SMC element 2 antibody
  • NSE2 antibody
  • RGD1305156 antibody
  • ZMIZ7 antibody

Protein level used designations for NSMCE2

E3 SUMO-protein ligase NSE2 , MMS21 homolog , non-structural maintenance of chromosomes element 2 homolog , non-SMC element 2 homolog , hMMS21 , methyl methanesulfonate sensitivity gene 21 , zinc finger, MIZ-type containing 7 , non-SMC element 2 homolog (MMS21, S. cerevisiae) , Non-structural maintenance of chromosomes element 2

GENE ID SPECIES
68501 Mus musculus
299957 Rattus norvegicus
286053 Homo sapiens
519974 Bos taurus
379272 Xenopus laevis
100724833 Cavia porcellus
2542312 Schizosaccharomyces pombe 972h-

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