anti-Notum Pectinacetylesterase Homolog (Drosophila) (NOTUM) Antibodies

May deacetylate GlcNAc residues on cell surface glycans (Potential).. Additionally we are shipping NOTUM Kits (6) and NOTUM Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NOTUM 147111 Q6P988
NOTUM 77583 Q8R116
NOTUM 303743  
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Top anti-NOTUM Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated IHC, WB 100 μg 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 0.1 mg 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (fro), WB 0.1 mg 6 to 8 Days
$467.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB   100 μg 15 to 19 Days
$527.03
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg 2 to 3 Days
$522.50
Details
Human Rabbit Un-conjugated ELISA, FM, IHC, WB Immunofluorescence of NOTUM Antibody Immunofluorescence Microscopy of NOTUM antibody. Tissue: mouse kidney cells. Fixation: 0.5% PFA. Antigen retrieval: not required. Primary antibody: NOTUM antibody at 20 µg/mL for 1 h at RT. Secondary antibody: Fluorescein rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: NOTUM is secreted into the extracellular space Staining: NOTUM as red fluorescent signal. Immunohistochemistry of NOTUM Antibody Immunohistochemistry of NOTUM antibody. Tissue: human brain tissue. Fixation: formalin fixed paraffin embedded. Antigen retrieval: not required. Primary antibody: NOTUM antibody at 2.5 µg/mL for 1 h at RT. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: NOTUM is secreted into the extracellular space. Staining: NOTUM as precipitated pink signal with purple nuclear counterstain. 100 μg 1 to 2 Days
$394.90
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Immunohistochemistry of NOTUM in human brain tissue with NOTUM polyclonal antibody  at 2.5 ug/mL . Western blot analysis of NOTUM in human kidney tissue lysate with NOTUM polyclonal antibody  at (A) 0.5 and (B) 1 ug/mL . 100 μg 11 to 12 Days
$356.00
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL 11 to 16 Days
$658.43
Details
Human Rabbit PE ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Details
Human Rabbit HRP ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Details

Top referenced anti-NOTUM Antibodies

  1. Human Polyclonal NOTUM Primary Antibody for IHC (fro), WB - ABIN538283 : Kozmik, Machon, Králová, Kreslová, Paces, Vlcek: Characterization of mammalian orthologues of the Drosophila osa gene: cDNA cloning, expression, chromosomal localization, and direct physical interaction with Brahma chromatin-remodeling complex. in Genomics 2001 (PubMed)
    Show all 3 Pubmed References

More Antibodies against NOTUM Interaction Partners

Human Notum Pectinacetylesterase Homolog (Drosophila) (NOTUM) interaction partners

  1. results reveal a role of the stem cell niche in ageing and demonstrate that targeting of Notum can promote regeneration of aged tissues

  2. NOTUM expression was increased in metastatic cells. Proliferation was suppressed by inhibiting expression of NOTUM. Knockdown of NOTUM genes inhibited proliferation as well as migration, with possible involvement of p38 and c-JUN N-terminal kinase in this process.

  3. Data show that notum and glypican-1 and glypican-3 gene expression during colorectal cancer (CRC) development and present evidence to suggest them as potential new biomarkers of CRC pathogenesis.

  4. Kinetic and mass spectrometric analyses of human proteins show that Notum is a carboxylesterase that removes an essential palmitoleate moiety from Wnt proteins and thus constitutes the first known extracellular protein deacylase

  5. Overexpression of NOTUM is associated with hepatocellular carcinoma

Mouse (Murine) Notum Pectinacetylesterase Homolog (Drosophila) (NOTUM) interaction partners

  1. results reveal a role of the stem cell niche in ageing and demonstrate that targeting of Notum can promote regeneration of aged tissues

  2. Notum influences mesenchymal cell differentiation by generating a barrier for Wnt ligands produced and secreted by airway epithelial cells to attenuate Wnt signaling.

  3. The findings support a significant role for NOTUM in modulating WNT signaling pathways that have pleiotropic effects on tooth and kidney development.

  4. Data show that notum and glypican-1 and glypican-3 gene expression during colorectal cancer (CRC) development and present evidence to suggest them as potential new biomarkers of CRC pathogenesis.

  5. Male mice deficient in Notum specifically in the liver develop metabolic dysfunctions implicating Notum in the development of Type 2 diabetes.

  6. Describes the human ortholog, and analyzes both the human and mouse promoters.

NOTUM Antigen Profile

Protein Summary

May deacetylate GlcNAc residues on cell surface glycans (Potential).

Gene names and symbols associated with NOTUM

  • notum, palmitoleoyl-protein carboxylesterase (NOTUM) antibody
  • notum pectinacetylesterase homolog (Drosophila) (Notum) antibody
  • NOTUM, palmitoleoyl-protein carboxylesterase (Notum) antibody
  • 5730593N15Rik antibody
  • RGD1307119 antibody

Protein level used designations for NOTUM

protein notum homolog , notum pectinacetylesterase homolog

GENE ID SPECIES
147111 Homo sapiens
77583 Mus musculus
303743 Rattus norvegicus
483374 Canis lupus familiaris
525682 Bos taurus
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