Nuclear Factor kappa B Proteins (NFkB)

NFkB encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. Additionally we are shipping Nuclear Factor kappa B Antibodies (43) and Nuclear Factor kappa B Kits (42) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NFkB 4790 P19838
NFkB 81736  
Mouse NFkB NFkB 18033 P25799
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Top Nuclear Factor kappa B Proteins at

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag,HIS-T7 100 μg Log in to see 15 to 18 Days
Escherichia coli (E. coli) Rat GST tag,His tag 100 μg Log in to see 15 to 18 Days
Escherichia coli (E. coli) Chicken His tag 100 μg Log in to see 15 to 18 Days

NFkB Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

More Proteins for Nuclear Factor kappa B (NFkB) Interaction Partners

Human Nuclear Factor kappa B (NFkB) interaction partners

  1. HMGB1 (show HMGB1 Proteins) promoted lung cancer invasion and metastasis by upregulating the expression and activity of MMP-2 (show MMP2 Proteins) in an NF-kappaB (show NFKB1 Proteins)-dependent manner.

  2. NF-kappaB (show NFKB1 Proteins) activation in breast cance (show CHORDC1 Proteins)r cells depends on the presence of the CHORDC1 gene product Morgana.

  3. Data suggest the angiopoietin-like 8 (ANGPTL8)/p62 (show GTF2H1 Proteins)-IKKgamma (show IKBKG Proteins) axis as a negative feedback loop that regulates NF-kappaB (show NFKB1 Proteins) activation, and extends the role of selective autophagy in fine-tuned inflammatory responses.

  4. Studied role of bone marrow stromal cell antigen 2 (BST2 (show BST2 Proteins)) in gastric cancer (GC); results show BST2 (show BST2 Proteins) is overexpressed in GC tissues and BST2 (show BST2 Proteins) silencing inhibits cell proliferation and migration, partly by regulating NF-kappaB (show NFKB1 Proteins) signaling.

  5. vaspin (show SERPINA12 Proteins) decreased miR (show MLXIP Proteins)-33a levels, which in turn increased ABCA1 (show ABCA1 Proteins) expression and cholesteorl efflux.

  6. these results define a tumor-supportive role for CDCA3 (show CDCA3 Proteins).

  7. NFKB1 (show NFKB1 Proteins) variants were significantly associated with type 2 diabetes

  8. NF-kappaB (show NFKB1 Proteins) has been identified as the main transcription factor regulating the induction of inflammation-related genes in intracranial aneurysms lesions. This transcription factor has also been related to intracranial aneurysms rupture and resulting Subarachnoid Hemorrhage. [review]

  9. miR (show MLXIP Proteins)-150 predicts survival in patients with sepsis and inhibits lipopolysaccharide-induced inflammatory factors and apoptosis by targeting NF-kappaB1 (show NFKB1 Proteins) in human umbilical vein endothelial cells.

  10. These results illustrate an alternative mechanism of HIV-1 Vpr regulation of Kaposi's sarcoma-associated herpesvirus (KSHV) latency and aberrant cytokines through the miR-711/Notch/NF-kappaB axis. Our novel findings further demonstrate the role of an HIV-1-secreted regulatory protein in the KSHV life cycle and KSHV-related malignancies.

Pig (Porcine) Nuclear Factor kappa B (NFkB) interaction partners

  1. Actinobacillus pleuropneumoniae induces alveolar Macrophages to produce proinflammatory cytokines via upregulation of TLR4 (show TLR4 Proteins) and NF-kappaB (show NFKB1 Proteins).

  2. Here, heat shock protein 27 (Hsp27) has been identified as a novel binding partner of NS5A, a protein functioning in classical swine fever virus genome replication. Further findings clearly demonstrate that the inhibition of viral replication by Hsp27 is mediated via the NF-kappaB signaling pathway.

  3. Porcine parvovirus virus infection significantly induced IL-6 (show IL6 Proteins) expression and this induction depended on NF-kappaB (show NFKB1 Proteins) activation and TLR9 (show TLR9 Proteins) signaling pathways in PK-15 cell.

  4. This study showed that porcine epidemic diarrhea virus inhibited NF-kappaB (show NFKB1 Proteins) activity and nsp1 was a potent NF-kappaB (show NFKB1 Proteins) antagonist for suppression of both interferon (show IFNA Proteins) and early production of pro-inflammatory cytokines.

  5. inhibition of NF-kappaB (show NFKB1 Proteins) increases autophagy via JNK (show MAPK8 Proteins) signaling, and promotes steroidogenesis in porcine granulosa cells

  6. SIRT1 (show SIRT1 Proteins), p53 (show TP53 Proteins) and NF-kappaB (show NFKB1 Proteins) are involved in the control of both the proliferation and the apoptosis of ovarian cells.

  7. porcine CD74 (show CD74 Proteins) significantly enhanced the inflammatory response by regulating the NF-kappaB (show NFKB1 Proteins) signalling pathway during PCV2 infection, which suggests that porcine CD74 (show CD74 Proteins) may be implicated in the pathogenesis of PCV2 infection.

  8. These results suggest that trans-10, cis (show CISH Proteins)-12-conjugated linoleic acid can modulate TNF-alpha (show TNF Proteins) production and NF-kappa B (show NFKB1 Proteins) expression by a PPARgamma (show PPARG Proteins)-dependent pathway in porcine peripheral blood mononuclear cells.

Mouse (Murine) Nuclear Factor kappa B (NFkB) interaction partners

  1. NF-kappaB (show NFKB1 Proteins) is responsible for Morgana (show CHORDC1 Proteins) dependent metastasis.

  2. study indicates that downregulation of NF-kappaB1 (show NFKB1 Proteins) can suppress renal cell carcinoma (show MOK Proteins) tumorigenesis by inducing late apoptosis/necrosis

  3. TNF-alpha (show TNF Proteins) is involved in cardiac PHLPP1 upregulation during reoxygenation, which is mediated by NF-kappaB (show NFKB1 Proteins) transcriptional activity

  4. Nuclear Factor kappa B (NF-kappaB (show NFKB1 Proteins)) pathway in the bone marrow (BM) vascular niche is a critical signalling axis that regulates haematopoietic stem cells (HSCs) function.

  5. NF-kappaB (show NFKB1 Proteins) and survivin are coordinately up-regulated in GBM patient tumors, and functional inhibition of either protein or BRD4 (show BRD4 Proteins) in in vitro and in vivo models restores sensitivity to EGFR (show EGFR Proteins) tyrosine kinase (show TYRO3 Proteins) inhibitors

  6. NF-kappaB1 (show NFKB1 Proteins) phosphorylation is regulated by platelet-activating factor in macrophages.

  7. Blockade of CD38 diminishes lipopolysaccharide-induced macrophage classical activation and acute kidney injury involving NF-kappaB (show NFKB1 Proteins) signaling suppression.

  8. NF-kappaBmiR15abFGF/VEGFA (show VEGFA Proteins) axis contributes to the impaired angiogenic capacity of bone marrowmesenchymal stem cells in high fat dietfed mice.

  9. ESP of fifth-stage larval Angiostrongylus cantonensis stimulates astrocyte activation and IL-1beta (show IL1B Proteins) and IL-6 (show IL6 Proteins) production through NF-kappaB (show NFKB1 Proteins) and the Shh (show SHH Proteins) signaling pathway.

  10. Tyr42 phosphorylation of RhoA GTPase promotes tumorigenesis through NF-kappaB (show NFKB1 Proteins).

Nuclear Factor kappa B (NFkB) Protein Profile

Protein Summary

This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Nuclear Factor kappa B Proteins (NFkB)

  • nuclear factor kappa B subunit 1 (NFKB1)
  • nuclear factor kappa B subunit 1 (Nfkb1)
  • nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 (Nfkb1)
  • EBP-1 protein
  • KBF1 protein
  • NF-kappa-B protein
  • NF-kappaB protein
  • NF-kappaB1 protein
  • NF-kB protein
  • NF-KB1 protein
  • NFkappaB protein
  • NFKB-p50 protein
  • NFKB-p105 protein
  • p50 protein
  • p50/p105 protein
  • p105 protein

Protein level used designations for Nuclear Factor kappa B Proteins (NFkB)

DNA binding factor KBF1 , DNA-binding factor KBF1 , NF-kappabeta , nuclear factor NF-kappa-B p105 subunit , nuclear factor NF-kappa-B p50 subunit , nuclear factor kappa-B DNA binding subunit , nuclear factor of kappa light chain gene enhancer in B-cells 1, p105 , nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 , NF-kB p50 subunit , nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) , nuclear factor kappa-B 1 , EBP-1 , NF kappaB1 , NF-kappa-B1 p84/NF-kappa-B1 p98 , NF-kappaB p50 , nuclear factor kappaB p50 , nuclear factor-kappaB p50 , p50 subunit of NF kappaB , p50 subunit of NF-kappaB

4790 Homo sapiens
81736 Rattus norvegicus
396033 Gallus gallus
442859 Canis lupus familiaris
751869 Sus scrofa
18033 Mus musculus
100730075 Cavia porcellus
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