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NFkB encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. Additionally we are shipping Nuclear Factor kappa B Antibodies (43) and Nuclear Factor kappa B Kits (42) and many more products for this protein.
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LMP1 (show PDLIM7 Proteins) functions to constitutively activate NF-kappaB (show NFKB1 Proteins) signalling during nasopharynx cancer pathogenesis.
NF-kappaB (show NFKB1 Proteins) signalling may repress ANT1 (show SLC25A4 Proteins) gene transcription and impair mitochondrial functions.
PGF (show PGF Proteins) promotes epithelial-mesenchymal transition-like changes in retinal pigment epithelium cells under hypoxia by activating the NF-kappaB (show NFKB1 Proteins) signaling pathway.
Data indicated that nestin (show NES Proteins) regulated NF-kappa B (NF-kappaB (show NFKB1 Proteins)) activity in foetal spinal cord tissues.
NF-kappaB p50 (show NFKB1 Proteins) and NF-kappaB (show NFKB1 Proteins) p65 (show GORASP1 Proteins) in thyroid carcinoma were positively associated with tumour diameter and the presence of lymph node metastasis
This study establishes PML (show PML Proteins) as an important regulator of NF-kappaB (show NFKB1 Proteins) and demonstrates that PML (show PML Proteins)-RARalpha (show RARA Proteins) dysregulates NF-kappaB (show NFKB1 Proteins).
Notch (show NOTCH1 Proteins) signaling can initiate Asb2 (show ASB2 Proteins) transcription and NF-kappa B (show NFKB1 Proteins) activation in T cell acute lymphoblastic leukemia cells.
Anti-rotavirus effect of TNF-alpha (show TNF Proteins) was achieved by NFkappaB (show NFKB1 Proteins)-regulated genes via the activation of classical nuclear factor kappaB (NF-kappaB (show NFKB1 Proteins)) signaling.
Knockdown of REG-GAMMA (REGgamma (show PSME3 Proteins)) may inhibit the proliferation and migration, and promote the apoptosis of plasma cell myeloma RPMI-8226 cells possibly by downregulating NF-kappa-B (NF-kappaB (show NFKB1 Proteins)) signal pathway.
L5-LDL, a naturally occurring mild oxidized LDL, induced G-CSF (show CSF3 Proteins) and GM-CSF (show CSF2 Proteins) production in human macrophages through LOX-1 (show OLR1 Proteins), ERK2 (show MAPK1 Proteins), and NF-kappaB (show NFKB1 Proteins) dependent pathways
Actinobacillus pleuropneumoniae induces alveolar Macrophages to produce proinflammatory cytokines via upregulation of TLR4 (show TLR4 Proteins) and NF-kappaB (show NFKB1 Proteins).
Here, heat shock protein 27 (Hsp27) has been identified as a novel binding partner of NS5A, a protein functioning in classical swine fever virus genome replication. Further findings clearly demonstrate that the inhibition of viral replication by Hsp27 is mediated via the NF-kappaB signaling pathway.
Porcine parvovirus virus infection significantly induced IL-6 (show IL6 Proteins) expression and this induction depended on NF-kappaB (show NFKB1 Proteins) activation and TLR9 (show TLR9 Proteins) signaling pathways in PK-15 cell.
This study showed that porcine epidemic diarrhea virus inhibited NF-kappaB (show NFKB1 Proteins) activity and nsp1 was a potent NF-kappaB (show NFKB1 Proteins) antagonist for suppression of both interferon (show IFNA Proteins) and early production of pro-inflammatory cytokines.
inhibition of NF-kappaB (show NFKB1 Proteins) increases autophagy via JNK (show MAPK8 Proteins) signaling, and promotes steroidogenesis in porcine granulosa cells
SIRT1 (show SIRT1 Proteins), p53 (show TP53 Proteins) and NF-kappaB (show NFKB1 Proteins) are involved in the control of both the proliferation and the apoptosis of ovarian cells.
porcine CD74 (show CD74 Proteins) significantly enhanced the inflammatory response by regulating the NF-kappaB (show NFKB1 Proteins) signalling pathway during PCV2 infection, which suggests that porcine CD74 (show CD74 Proteins) may be implicated in the pathogenesis of PCV2 infection.
These results suggest that trans-10, cis (show CISH Proteins)-12-conjugated linoleic acid can modulate TNF-alpha (show TNF Proteins) production and NF-kappa B (show NFKB1 Proteins) expression by a PPARgamma (show PPARG Proteins)-dependent pathway in porcine peripheral blood mononuclear cells.
Macrophage-derived IL1B (show IL1B Proteins)/NF-kappaB (show NFKB1 Proteins) signaling mediates parenteral nutrition-associated cholestasis in a mouse model.
SIRT1 (show SIRT1 Proteins) upregulation protects against liver injury induced by a HFD through inhibiting CD36 (show CD36 Proteins) and the NF-kappaB (show NFKB1 Proteins) pathway in mouse Kupffer cells.
activation of NF-kappaB pathway is essential for Bacterial lipoprotein tolerance-augmented antimicrobial activity in innate phagocytes and depends primarily on both NOD1 and NOD2.
High host NF-kappaB p50 (show NFKB1 Proteins) induces murine glioblastoma tumor.
NF-kappaB (show NFKB1 Proteins) is responsible for Morgana (show CHORDC1 Proteins) dependent metastasis.
study indicates that downregulation of NF-kappaB1 (show NFKB1 Proteins) can suppress renal cell carcinoma (show MOK Proteins) tumorigenesis by inducing late apoptosis/necrosis
TNF-alpha (show TNF Proteins) is involved in cardiac PHLPP1 upregulation during reoxygenation, which is mediated by NF-kappaB (show NFKB1 Proteins) transcriptional activity
Nuclear Factor kappa B (NF-kappaB (show NFKB1 Proteins)) pathway in the bone marrow (BM) vascular niche is a critical signalling axis that regulates haematopoietic stem cells (HSCs) function.
NF-kappaB (show NFKB1 Proteins) and survivin are coordinately up-regulated in GBM patient tumors, and functional inhibition of either protein or BRD4 (show BRD4 Proteins) in in vitro and in vivo models restores sensitivity to EGFR (show EGFR Proteins) tyrosine kinase (show TYRO3 Proteins) inhibitors
NF-kappaB1 (show NFKB1 Proteins) phosphorylation is regulated by platelet-activating factor in macrophages.
This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.
DNA binding factor KBF1
, DNA-binding factor KBF1
, nuclear factor NF-kappa-B p105 subunit
, nuclear factor NF-kappa-B p50 subunit
, nuclear factor kappa-B DNA binding subunit
, nuclear factor of kappa light chain gene enhancer in B-cells 1, p105
, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105
, NF-kB p50 subunit
, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)
, nuclear factor kappa-B 1
, NF kappaB1
, NF-kappa-B1 p84/NF-kappa-B1 p98
, NF-kappaB p50
, nuclear factor kappaB p50
, nuclear factor-kappaB p50
, p50 subunit of NF kappaB
, p50 subunit of NF-kappaB