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Down-regulates transcriptional activation by nuclear receptors such as NR1F2 (By similarity)..
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Human Polyclonal NRIP2 Primary Antibody for ICC, IF - ABIN4340696
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
Results show that NRIP2 was significantly up-regulated in Colorectal cancer initiating cells (CCICs) from both cell lines and primary colorectal cancer tissues, and identified it as a novel molecule acting in Wnt pathway. The interaction between NRIP2 and RORbeta activates downstream target HBP1 and is probably involved in CCIC self-renewal.
Down-regulates transcriptional activation by nuclear receptors such as NR1F2 (By similarity).
nuclear receptor interacting protein 2
, nuclear receptor-interacting protein 2
, neuronal interacting factor 1
, neuronal-interacting factor X 1
, nuclear receptor interacting protein 2-like