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NAF1 encodes an A20-binding protein which plays a role in autoimmunity and tissue homeostasis through the regulation of nuclear factor kappa-B activation. Additionally we are shipping Nuclear ssembly factor 1 ribonucleoprotein Antibodies (8) and many more products for this protein.
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the current study has identified that rs2320615 in the NAF1 was associated with the risk of esophageal cancer in the Han Chinese population.
These findings point to a key role for the unique 3Cys-1His cluster of NAF-1 (show TNIP1 Proteins) in promoting rapid tumor growth through cellular resistance to oxidative stress.
Data indicate that disease in NAF1 (show TNIP1 Proteins) mutation carriers is telomere-mediated; they show that NAF1 (show TNIP1 Proteins) haploinsufficiency selectively disturbs telomere length homeostasis by decreasing the levels of telomerase RNA while sparing rRNA pseudouridylation.
RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4 (By similarity).
H/ACA ribonucleoprotein complex non-core subunit NAF1
, nuclear assembly factor 1 homolog