Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing Proteins (NACC1)

The vertebrate sodium channel is a voltage-gated ion channel essential for the generation and propagation of action potentials, mainly in nerve and muscle. Additionally we are shipping Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing Antibodies (93) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NACC1 112939 Q96RE7
NACC1 66830 Q7TSZ8
NACC1 171454 O35260
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Top Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing Proteins at antibodies-online.com

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Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$8,498.50
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Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$8,498.50
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Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,461.33
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NACC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Mouse (Murine)

Rat (Rattus)

More Proteins for Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) Interaction Partners

Human Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) interaction partners

  1. NAC1 forms a protein complex to function as a transcriptional regulator in cancer cells

  2. a mutation in NACC1 causes microcephaly, profound developmental delays and/or intellectual disability, cataracts, severe epilepsy including infantile spasms, irritability, failure to thrive, and stereotypic hand movements

  3. miR (show MLXIP Proteins)-339-5p inhibits migration and invasion in ovarian cancer by targeting NACC1 and BCL6 (show BCL6 Proteins). miR (show MLXIP Proteins)-339-5p may be a biomarker of metastasis in ovarian cancer; NACC1 had a predictive value for ovarian cancer progression

  4. NAC1 has potential as a marker for distinguishing OED from CIS (show CISH Proteins)/OSCC

  5. NACC1 can be modified by SUMO paralogues, and cooperates with promyelocytic leukemia protein (show PML Proteins).

  6. strategy for the purification of tethered POZ domains that form forced heterodimers is described, and crystal structures of the heterodimeric POZ domains of Miz1 (show ZBTB17 Proteins)/BCL6 (show BCL6 Proteins) and of Miz1 (show ZBTB17 Proteins)/NAC1 are reported

  7. NAC1 is essential and sufficient for activation of FOXQ1 (show FOXQ1 Proteins)

  8. low expression of NAC1 predicts poor prognosis for patients with pancreatic ductal adenocarcinoma.

  9. The identification of an NAC1 NLS (show ALDH1A2 Proteins) thus clarifies the mechanism through which NAC1 translocates to the nucleus to regulate the transcription of genes involved in oncogenicity and pluripotency.

  10. Uterine sarcomas with NAC1 overexpression are clinically the most aggressive, chemoresistant, and radioresistant tumors.

Mouse (Murine) Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) interaction partners

  1. a sub-network of four factors, Nac1, Oct4 (show POU5F1 Proteins), Tcf3 (show TCF7L1 Proteins), and Sox2 (show SOX2 Proteins), regulates mouse embryonic stem cell differentiation into the alternative mesendodermal and neuroectodermal fates.

  2. The interaction of Nac1 with Miz1 (show PIAS2 Proteins) may thus be relevant to its mechanism of tumourigenesis in ovarian cancer.

  3. NAC1 participates in the motility and differentiation of developing chondrocytes and cartilaginous tissues, and its expression is necessary to maintain normal axial patterning of murine skeleton.

  4. The mouse Nac1 gene consist of six exons, with exon 2 containing an alternative splice donor, providing a molecular explanation of the splice variants observed in mouse and rat.

  5. these data indicate involvement of NAC1 in the acute behavioral and neurochemical responses to psychomotor stimulants

  6. Nanog (show NANOG Proteins) interacts with Nac1 through WNAAP to regulate the cell cycle of stem cells via the ERas/phosphatidylinositol 3-kinase/Akt (show AKT1 Proteins) pathway, but not pluripotency

Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) Protein Profile

Protein Summary

This gene encodes a member of the BTB/POZ protein family. BTB/POZ proteins are involved in several cellular processes including proliferation, apoptosis and transcription regulation. The encoded protein is a transcriptional repressor that plays a role in stem cell self-renewal and pluripotency maintenance. The encoded protein also suppresses transcription of the candidate tumor suppressor Gadd45GIP1, and expression of this gene may play a role in the progression of multiple types of cancer. A pseudogene of this gene is located on the short arm of chromosome 9.

Gene names and symbols associated with NACC1

  • nucleus accumbens associated 1 (NACC1)
  • nucleus accumbens associated 1, BEN and BTB (POZ) domain containing (Nacc1)
  • nucleus accumbens associated 1 (Nacc1)
  • 2010001H03Rik protein
  • 4930511N13Rik protein
  • BEND8 protein
  • Btbd14b protein
  • BTBD30 protein
  • Nac-1 protein
  • Nac1 protein
  • NACC1 protein

Protein level used designations for NACC1

BEN domain containing 8 , BTB/POZ domain-containing protein 14B , nucleus accumbens-associated protein 1 , transcriptional repressor NAC1 , nucleus accumbens associated 1, BEN and BTB (POZ) domain containing , BTB (POZ) domain containing 14B , NAC-1 , nucleus accumbens-1

GENE ID SPECIES
112939 Homo sapiens
484918 Canis lupus familiaris
525378 Bos taurus
66830 Mus musculus
171454 Rattus norvegicus
100063244 Equus caballus
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