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The product of NUDCD3 functions to maintain the stability of dynein intermediate chain. Additionally we are shipping NUDCD3 Antibodies (18) and and many more products for this protein.
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overexpression of NudCL inhibits cytokinesis
Data characterize a previously undescribed mammalian NudC-like protein (NudCL), which appears to influence the stabilization of dynein intermediate chain
The product of this gene functions to maintain the stability of dynein intermediate chain. Depletion of this gene product results in aggregation and degradation of dynein intermediate chain, mislocalization of the dynein complex from kinetochores, spindle microtubules, and spindle poles, and loss of gamma-tubulin from spindle poles. The protein localizes to the Golgi apparatus during interphase, and levels of the protein increase after the G1/S transition.
, nudC domain-containing protein 3