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Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. Additionally we are shipping OAZ2 Antibodies (25) and many more products for this protein.
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Gene expression studies have identified altered expression of ornithine decarboxylase antizyme 2 in suicide completers with a history of mood disorders.
This study demomistrated that H3K4me3 modification plays an important role in up regulation of OAZ2 in prefrontal cortex.
elevated ODC (show ODC1 Proteins) and low OAZ2 mRNA expression levels correlate with several unfavorable genetic and clinical features in neuroblastoma (show ARHGEF16 Proteins).
The level of AZ2 mRNA decreased during mammary gland development.
Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits ornithine decarboxylase but does not accelerate its degradation.
ornithine decarboxylase antizyme 2 , ODC-Az 2 , antizyme 2 , seizure-related protein 15 , AZ2 , ODC antizyme, long form , ODC-Az-L