OAZ2 Protein (AA 1-189) (His tag)

Catalog No. ABIN7550230

This Recombinant OAZ2 protein is produced in HEK-293 Cells.

Quick Overview for OAZ2 Protein (AA 1-189) (His tag) (ABIN7550230)

Target: OAZ2 (Ornithine Decarboxylase Antizyme 2 (OAZ2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Product Details

Protein Characteristics: AA 1-189

Purification tag / Conjugate: This OAZ2 protein is labelled with His tag.

Purpose: Predefined custom protein recombinant OAZ2 Protein expressed in mammalian cells.

Sequence: MINTQDSSIL PLSNCPQLQC CRHIVPGPLW CSDAPHPLSK IPGGRGGGRD PSLSALIYKD EKLTVTQDLP VNDGKPHIVH FQYEVTEVKV SSWDAVLSSQ SLFVEIPDGL LADGSKEGLL ALLEFAEEKM KVNYVFICFR KGREDRAPLL KTFSFLGFEI VRPGHPCVPS RPDVMFMVYP LDQNLSDED Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: OAZ2 (Ornithine Decarboxylase Antizyme 2 (OAZ2))

Alternative Name: OAZ2

Background: Ornithine decarboxylase antizyme 2 (AZ2) (ODC-Az 2),FUNCTION: Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimers. Does not target the ODC monomers for degradation, which allows a protein synthesis-independent restoration of ODC activity (PubMed:17900240). Involved in the translocation of AZIN2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol (By similarity). {ECO:0000250|UniProtKB:O08608, ECO:0000269|PubMed:17900240}.

Molecular Weight: 21.0 kDa

UniProt: O95190

AlphaFold: O95190