anti-Oxysterol Binding Protein (OSBP) Antibodies

Oxysterol binding protein is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase [provided by RefSeq, Jul 2008]. Additionally we are shipping Oxysterol Binding Protein Proteins (6) and Oxysterol Binding Protein Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
OSBP 5007 P22059
OSBP 76303 Q3B7Z2
OSBP 365410  
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Top anti-Oxysterol Binding Protein Antibodies at antibodies-online.com

Showing 10 out of 69 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
€255.75
Details
Human Goat Un-conjugated ELISA, WB ABIN185113 (2µg/ml) staining of Human Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
€380.39
Details
Human Goat Un-conjugated ELISA, WB ABIN185379 (0.1µg/ml) staining of Human Placenta lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
€380.39
Details
Human Goat Un-conjugated ELISA, WB Western Blot: OSBP Antibody [ABIN250354] - ABIN250354 (0.1ug/ml) staining of Hela lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Western Blot: OSBP1 Antibody [ABIN250354] - Analysis of Human Placenta lysate (35ug protein in RIPA buffer) using ABIN250354 (0.1ug/ml). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
€432.50
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
€488.35
Details
Human Goat Un-conjugated IP, ELISA, WB Western Blot: OSBP1 Antibody [ABIN250053] - (2ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
€432.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 11 to 14 Days
€449.41
Details
Cow Goat Un-conjugated ELISA, WB 100 μg Log in to see 11 to 14 Days
€540.27
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 11 to 14 Days
€540.27
Details
Human Rabbit Un-conjugated IHC, WB ABIN6272972 at 1/100 staining Mouse colon tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of extracts of HeLa cells, using OSBP antibody. 100 μL Log in to see 11 to 12 Days
€345.81
Details

Top referenced anti-Oxysterol Binding Protein Antibodies

  1. Human Polyclonal OSBP Primary Antibody for ELISA, WB - ABIN250354 : Romeo, Kazlauskas: Oxysterol and diabetes activate STAT3 and control endothelial expression of profilin-1 via OSBP1. in The Journal of biological chemistry 2008 (PubMed)
    Show all 5 Pubmed References

  2. Cow (Bovine) Polyclonal OSBP Primary Antibody for WB - ABIN611390 : Watanabe, Ikejima, Suzuki, Shimada: Genomic organization and expression of the human MSH3 gene. in Genomics 1997 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal OSBP Primary Antibody for IP, ELISA - ABIN250053 : Moreira, Jaworski, Li, Rodriguez: Molecular and biochemical characterization of a novel oxysterol-binding protein (OSBP2) highly expressed in retina. in The Journal of biological chemistry 2001 (PubMed)
    Show all 2 Pubmed References

  4. Dog (Canine) Polyclonal OSBP Primary Antibody for ELISA, WB - ABIN547424 : Wang, Weng, Anderson: OSBP is a cholesterol-regulated scaffolding protein in control of ERK 1/2 activation. in Science (New York, N.Y.) 2005 (PubMed)

More Antibodies against Oxysterol Binding Protein Interaction Partners

Fruit Fly (Drosophila melanogaster) Oxysterol Binding Protein (OSBP) interaction partners

  1. Study identified an OSBP- and FAN-mediated sterol requirement in Drosophila spermatogenesis

Human Oxysterol Binding Protein (OSBP) interaction partners

  1. the component proteins of the machinery, OSBP, VAP, SAC1, and PITPNB, are all essential host factors for AiV replication. Importantly, the machinery is directly recruited to the RNA replication sites through previously unknown interactions of VAP/OSBP/SAC1 with the AiV proteins and with ACBD3.

  2. results demonstrate that Sac1 expression in either the ER or Golgi apparatus has a minimal impact on the PI-4P that regulates OSBP activity or recruitment to contact sites

  3. Cholesterol transfer, PI4P consumption, and control of membrane lipid order by endogenous OSBP have been described.

  4. Data suggest that OSBP shifts the distribution of phosphatidylinositol 4-phosphate upon localization to endoplasmic reticulum-Golgi contact sites.

  5. Our results identify OspB as a regulator of mTORC1 and mTORC1-dependent cell proliferation early during S. flexneri infection and establish a role for IQGAP1 in mTORC1 signaling

  6. These results suggest that poliovirus proteins modulate PI4KB activity and provide PI4P for recruitment of OSBP to accumulate unesterified cholesterol on virus-induced membrane structure for formation of a virus replication complex.

  7. OSBP-mediated back transfer of phosphatidylinositol 4-phosphate might coordinate the transfer of other lipid species at the endoplasmic reticulum-Golgi interface.

  8. OSBP is required for efficient replication of intracellular S. Typhimurium.

  9. Data indicate that phosphorylation on two serine-rich motifs, S381-S391 (site 1) and S192, S195, S200 (site 2), specifically controls oxysterol-binding protein (OSBP) activity at the endoplasmic reticulum (ER).

  10. PKD negatively regulates HCV secretion/release by attenuating OSBP and CERT functions by phosphorylation inhibition. This study identifies the key role of the Golgi components in the HCV maturation process.

  11. Results identify a novel substrate of protein kinase D at the Golgi, the oxysterol-binding protein OSBP.

  12. This review summarizes recent evidence of sterol transfer activity by OSBP, suggesting seemingly disparate functions that could be the result of alterations in membrane sterol distribution or ancillary to this primary activity.

  13. Electrostatic interaction between oxysterol-binding protein and VAMP-associated protein A revealed by NMR and mutagenesis studies.

  14. OSBP was found to function as a cholesterol-binding scaffolding protein coordinating the activity of two phosphatases to control the extracellular signal-regulated kinase (ERK) signaling pathway

  15. Regulation of ceramide transport protein by OSBP, sterols, and vesicle-associated protein reveals a novel mechanism for integrating sterol regulatory signals with ceramide transport and phingomyelin synthesis in the Golgi apparatus.

  16. OSBP is able to sense both membrane cholesterol and oxidized sterols and link this information to the ERK1/2 signaling pathway.

  17. functional role of OSBP in the HCV maturation process.

Mouse (Murine) Oxysterol Binding Protein (OSBP) interaction partners

  1. OSBP may be a target and downstream effector of miR-124 for regulating neurite outgrowth and elongation.

  2. roles of different ORP proteins as regulators of macrophage lipid composition, with implications for inflammatory signaling

  3. Partitioning of Osbp between the endoplasmic reticulum and the Golgi apparatus is regulated by Vapa.

  4. OSBP opposes the activity of LXR by negatively regulating ABCA1 activity in the cytoplasm by sterol-binding domain-dependent protein destabilization

Rabbit Oxysterol Binding Protein (OSBP) interaction partners

  1. Oxysterol-binding protein is required for the perinuclear localization of intra-Golgi v-SNAREs.

Oxysterol Binding Protein (OSBP) Antigen Profile

Protein Summary

Oxysterol binding protein is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase

Gene names and symbols associated with OSBP

  • Oxysterol binding protein (Osbp) antibody
  • oxysterol binding protein (OSBP) antibody
  • oxysterol binding protein (Osbp) antibody
  • 1110018F06Rik antibody
  • AW559088 antibody
  • CG6708 antibody
  • Dmel\\CG6708 antibody
  • mKIAA4220 antibody
  • osbp antibody
  • OSBP-Dm antibody
  • OSBP1 antibody

Protein level used designations for OSBP

CG6708-PA , Osbp-PA , oxysterol binding protein , oxysterol-binding protein , oxysterol-binding protein 1

GENE ID SPECIES
42985 Drosophila melanogaster
5007 Homo sapiens
483448 Canis lupus familiaris
530000 Bos taurus
76303 Mus musculus
365410 Rattus norvegicus
451213 Pan troglodytes
100009048 Oryctolagus cuniculus
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