anti-P21-Activated Kinase 6 (PAK6) Antibodies

PAK6 represents readthrough transcription between the genes BUB1B (mitotic checkpoint serine/threonine-protein kinase BUB1 beta) and PAK6 (serine/threonine-protein kinase PAK 6). Additionally we are shipping P21-Activated Kinase 6 Proteins (9) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PAK6 56924 Q9NQU5
PAK6 214230 Q3ULB5
PAK6 296078  
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Top anti-P21-Activated Kinase 6 Antibodies at antibodies-online.com

Showing 10 out of 178 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated EIA, IP, WB 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of PAK6 expression in HeLa (A), LOVO (B), mouse brain (C), rat brain (D) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-PAK6 antibody, IHC(P) IHC(P): Rat Brain Tissue 100 μg 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB   0.4 mL 16 Days
$522.50
Details
Cow Rabbit Un-conjugated WB Host:  Rabbit  Target Name:  PAK6  Sample Type:  HepG2 Whole Cell lysates  Antibody Dilution:  1.0ug/ml 100 μL 2 to 3 Days
$289.00
Details
Dog Rabbit Un-conjugated IHC, IHC (p) Anti-PAK6 antibody  ABIN1049227 IHC staining of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-PAK6 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Anti-PAK6 antibody  ABIN1049228 IHC staining of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-PAK6 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from mouse lung, using PAK6 (Phospho-Ser165) Antibody. Western blot analysis of PAK6 (Phospho-Ser165) using UV treated Jurkat whole cell lysates 100 μL 11 to 12 Days
$450.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg 4 to 8 Days
$522.50
Details
Bat Rabbit Un-conjugated ELISA, IHC, IHC (p) Human Testis (formalin-fixed, paraffin-embedded) stained with PAK6 antibody ABIN213527 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-PAK6 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 to 14 Days
$484.00
Details

Top referenced anti-P21-Activated Kinase 6 Antibodies

  1. Human Polyclonal PAK6 Primary Antibody for IHC (fro), IF - ABIN541200 : Yang, Li, Sharma, Zarnegar, Lim, Sun: Androgen receptor specifically interacts with a novel p21-activated kinase, PAK6. in The Journal of biological chemistry 2001 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal PAK6 Primary Antibody for IP, ELISA - ABIN543265 : Ching, Leong, Wong, Kung: Identification of an autoinhibitory domain of p21-activated protein kinase 5. in The Journal of biological chemistry 2003 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal PAK6 Primary Antibody for ELISA, WB - ABIN548449 : Lee, Ramos, Ko, Masiello, Swanson, Lu, Balk: AR and ER interaction with a p21-activated kinase (PAK6). in Molecular endocrinology (Baltimore, Md.) 2002 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal PAK6 Primary Antibody for ELISA, WB - ABIN548431 : Schrantz, da Silva Correia, Fowler, Ge, Sun, Bokoch: Mechanism of p21-activated kinase 6-mediated inhibition of androgen receptor signaling. in The Journal of biological chemistry 2004 (PubMed)
    Show all 3 Pubmed References

  5. Human Polyclonal PAK6 Primary Antibody for IHC, ELISA - ABIN1002959 : Jaffer, Chernoff: p21-activated kinases: three more join the Pak. in The international journal of biochemistry & cell biology 2002 (PubMed)
    Show all 3 Pubmed References

  6. Human Polyclonal PAK6 Primary Antibody for EIA, IP - ABIN360326 : Pandey, Dan, Kristiansen, Watanabe, Voldby, Kajikawa, Khosravi-Far, Blagoev, Mann: Cloning and characterization of PAK5, a novel member of mammalian p21-activated kinase-II subfamily that is predominantly expressed in brain. in Oncogene 2002 (PubMed)
    Show all 4 Pubmed References

  7. Dog (Canine) Polyclonal PAK6 Primary Antibody for IHC (p) - ABIN4343483 : Kwek, Dao, Roy, Hou, Alajajian, Simko, Small, Fong: Diversity of antigen-specific responses induced in vivo with CTLA-4 blockade in prostate cancer patients. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)

  8. Human Polyclonal PAK6 Primary Antibody for ELISA, ICC - ABIN4343485 : Raja, Sahasrabuddhe, Radhakrishnan, Syed, Solanki, Puttamallesh, Balaji, Nanjappa, Datta, Babu, Renuse, Patil, Izumchenko, Prasad, Chang, Rangarajan, Sidransky, Pandey, Gowda, Chatterjee: Chronic exposure to cigarette smoke leads to activation of p21 (RAC1)-activated kinase 6 (PAK6) in non-small cell lung cancer cells. in Oncotarget 2016 (PubMed)

More Antibodies against P21-Activated Kinase 6 Interaction Partners

Human P21-Activated Kinase 6 (PAK6) interaction partners

  1. inhibition of PAK6 leads to reduction in cell proliferation, migration and invasion of cigarette smoke treated non-small cell lung cancer cells

  2. Study shows that high PAK6 expression is associated with poor prognosis and increased chemoresistance to 5-FU/oxaliplatin chemotherapy of gastric tumor.

  3. RhoD recruits Pak6 to the plasma membrane to antagonize RhoC signaling during cell contraction and blebbing

  4. PAK6 localization to cell-cell adhesions is Cdc42-dependent

  5. p21-activated kinase 6 (PAK6) as a novel interactor of leucine-rich repeat kinase 2 (LRRK2), a kinase involved in Parkinson's disease

  6. PAK6 is directly targeted by miR-328. miR-328 inhibits cell growth and promotes cell apoptosis in prostate cancer cells.

  7. negative correlation between PAK6 and EZH2 expression was observed in hepatoma tissues from HCC patients. These data identified the tumor suppressive role and potential underlying mechanism of PAK6 in hepatocarcinogenesis

  8. the results of the present study suggested that miR-429 inhibits the migration and invasion of colon cancer cells, partly at least, by mediating the expression of PAK6, as well as the activity of cofilin signaling

  9. we report that in colon cancer PAK6 promotes tumor progression and chemoresistance both in vitro and in vivo

  10. PAK6 is specifically required for carcinoma cell-cell dissociation downstream of hepatocyte growth factor (HGF) for both DU145 prostate cancer and HT29 colon cancer cells.

  11. PAK5 plays an essential role in the initiation and progression of hepatocellular carcinoma.

  12. These results demonstrate that androgen-stimulated PAK6 activation is mediated through a direct interaction between AR and PAK6 and PAK6 activation promotes prostate cancer cells motility and invasion.

  13. PAK6 is overexpressed in hepatocellular carcinoma, compared with the adjacent noncancerous liver tissues, and is associated with poor prognosis.

  14. PAK6 phosphorylates Mdm2 on Thr-158 and Ser-186, which is critical for AR ubiquitin-mediated degradation.

  15. Hypermethylation of PAK6 gene is associated with adenocarcinoma.

  16. Results indicate that all of the 3 prostate cancer specimens showed positive staining in the stroma, suggesting that PAK6 may participate in the stroma-cancer cell interaction in prostate cancer.

  17. The activation of PAK6 by both p38 MAP kinase and MKK6 suggests that PAK6 plays a role in the cellular response to stress-related signals.

  18. PAK5 is a potent regulator of Raf-1 activity and may control Raf-1 dependent signaling at mitochondria

  19. PAK6 was weakly expressed in normal prostate epithelium. Its expression was increased in primary and metastatic prostate cancer, and was further increased in tumors that relapsed after androgen deprivation therapy.

Mouse (Murine) P21-Activated Kinase 6 (PAK6) interaction partners

  1. p21-activated kinase 6 (PAK6) as a novel interactor of leucine-rich repeat kinase 2 (LRRK2), a kinase involved in Parkinson's disease

  2. data suggest that PAK-6 p21-activated kinase plays a role in weight gain unrelated to exercise and caloric intake

  3. functional deficits in PAK5, PAK6 and PAK5/PAK6 knockout mice

  4. Our results indicate that Pak5 and Pak6 together are not required for viability, but are required for a normal level of locomotion and activity as well as for learning and memory.

P21-Activated Kinase 6 (PAK6) Antigen Profile

Protein Summary

This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PAK6

  • p21 (RAC1) activated kinase 6 (PAK6) antibody
  • p21 protein (Cdc42/Rac)-activated kinase 6 (Pak6) antibody
  • p21 (RAC1) activated kinase 6 (Pak6) antibody
  • p21 protein (Cdc42/Rac)-activated kinase 6b (pak6b) antibody
  • p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6) antibody
  • 4732456M09 antibody
  • PAK5 antibody
  • pak6 antibody
  • si:ch211-158b22.3 antibody

Protein level used designations for PAK6

p21(CDKN1A)-activated kinase 6 , serine/threonine-protein kinase PAK 6 , PAK-6 , p21-activated kinase 6 , p21 (CDKN1A)-activated kinase 6 , p21 protein (Cdc42/Rac)-activated kinase 6

GENE ID SPECIES
56924 Homo sapiens
214230 Mus musculus
296078 Rattus norvegicus
567874 Danio rerio
100172971 Pongo abelii
100348921 Oryctolagus cuniculus
428837 Gallus gallus
100071463 Equus caballus
100153981 Sus scrofa
539224 Bos taurus
487490 Canis lupus familiaris
100713585 Cavia porcellus
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