anti-PDZ Domain Containing 2 (PDZD2) Antibodies

Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PDZD2 23037 O15018
PDZD2 68070  
PDZD2 65034 Q9QZR8
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Top anti-PDZD2 Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Goat Un-conjugated ELISA   100 μg 6 to 7 Days
$291.53
Details
Human Rabbit Un-conjugated IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human heart tissue, using PDZD2 Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of HepG2 cells, using PDZD2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: A549 5% SDS PAGE antibody diluted at 1:1000 100 μL 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, IHC (p) 100 μL 11 to 14 Days
$493.17
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC ABIN6266697 staining HeLa cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibody. ABIN6266697 at 1/100 staining human lymph node tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated ELISA, IF, IHC   100 μL Available
$363.46
Details
Bat Goat Un-conjugated ELISA   100 μg 11 to 14 Days
$507.83
Details
Human Rabbit Un-conjugated WB   100 μL 11 to 14 Days
$537.17
Details
Human Rabbit Cy5 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit Cy7 IF (p)   100 μL 14 to 21 Days
$416.90
Details

Top referenced anti-PDZD2 Antibodies

  1. Human Polyclonal PDZD2 Primary Antibody for ELISA - ABIN547222 : Deguchi, Iizuka, Hata, Nishimura, Hirao, Yao, Kawabe, Takai: PAPIN. A novel multiple PSD-95/Dlg-A/ZO-1 protein interacting with neural plakophilin-related armadillo repeat protein/delta-catenin and p0071. in The Journal of biological chemistry 2000 (PubMed)

More Antibodies against PDZD2 Interaction Partners

Human PDZ Domain Containing 2 (PDZD2) interaction partners

  1. Study results revealed that MG-63 osteosarcoma cells contained low levels of miR-363, and that overexpression of miR-363 in MG-63 cells significantly inhibited the vitality, proliferation, and colony formation ability of the cells. Bioinformatics analysis and luciferase reporter assay indicated that PDZD2 was a direct target of miR-363. In vivo xenograft model further confirmed that miR-363 functioned as tumor suppressor.

  2. we systematically evaluating RCC risk-associated SNPs indentified from previous GWAS in a Chinese population, finding that one SNP located in PDZD2 and two SNPs located in ITPR2 were ccRCC-risk associated in Chinese population.

  3. The DNA copy number variations disrupt PDZD2 and GOLPH3 genes predominantly expressed in placenta, and it may represent a novel risk factor for recurrent miscarriage.

  4. This study does not support the association of PDZD2, GOLPH3, and MTMR12 genes with schizophrenia.

  5. the first reported multi-PDZ protein that is processed by proteolytic cleavage to generate a secreted peptide containing two PDZ domains

  6. The mitogenic effect of secreted PDZD2 was concentration-dependent, and was associated with a slight inhibition of the insulin promoter activity at high sPDZD2 concentrations.

  7. Results show that a novel pancreatic developmental factor, PDZD2, is sufficient to promote the proliferation of human fetal PPCs while limiting differentiation of ICCs into islet/endocrine cells.

  8. sPDZD2 sensitized mutant p53-positive DU145 cells and wild-type p53-positive MCF-7 cells to apoptosis induction through genotoxic stress imposed by sub-lethal concentration of hydrogen peroxide

  9. PDZ-domain containing-2 (PDZD2) drives the maturity of human fetal pancreatic progenitor-derived islet-like cell clusters with functional responsiveness against membrane depolarization.

Mouse (Murine) PDZ Domain Containing 2 (PDZD2) interaction partners

  1. Results provide the first evidence that Pdzd2 is required for normal regulation of basal insulin secretion.

  2. These findings reveal that Pdzd2 and p11 play collaborative roles in regulation of Na(V)1.8 expression in sensory neurons.

PDZD2 Antigen Profile

Protein Summary

Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.

Gene names and symbols associated with PDZD2

  • PDZ domain containing 2 (PDZD2) antibody
  • PDZ domain containing 2 (Pdzd2) antibody
  • 4930537L06Rik antibody
  • A930022H17Rik antibody
  • AIPC antibody
  • Gm82 antibody
  • mKIAA0300 antibody
  • Papin antibody
  • Pdzk3 antibody
  • PIN1 antibody

Protein level used designations for PDZD2

PDZ domain containing 3 , PDZ domain-containing protein 2 , PDZ domain-containing protein 3 , activated in prostate cancer protein , plakophilin-related armadillo repeat protein-interacting PDZ protein

GENE ID SPECIES
23037 Homo sapiens
68070 Mus musculus
65034 Rattus norvegicus
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