anti-Paroxysmal Nonkinesigenic Dyskinesia (PNKD) Antibodies

PNKD is thought to play a role in the regulation of myofibrillogenesis. Additionally we are shipping PNKD Kits (6) and PNKD Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PNKD 25953 Q8N490
PNKD 56695 Q69ZP3
PNKD    
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Top anti-PNKD Antibodies at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Pnkd Antibody   Titration: 1.0 ug/ml   Positive Control: Mouse Heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue reacted with PNKD Antibody (N-term) followed which was peroxidase conjugated to the secondary antibody and followed by DAB staining. This data demonstrates the use of PNKD Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis of PNKD Antibody (N-term) in mouse liver tissue lysates (35ug/lane). This demonstrates the PNKD antibody detected the PNKD protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Mouse Rabbit Un-conjugated IHC (p), WB PNKD Antibody (N-term)  western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PNKD antibody detected the PNKD protein (arrow). PNKD Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PNKD Antibody (N-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: PNKD Antibody [NBP1-88347] - Staining of human cell line U-2 OS shows positivity in mitochondria. Immunohistochemistry-Paraffin: PNKD Antibody [NBP1-88347] - Immunohistochemical staining of human vagina shows strong cytoplasmic positivity in squamous epithelial cells. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Horse Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: PNKD Antibody [NBP1-88348] Staining of human cell line U-251MG shows positivity in mitochondria. Immunohistochemistry-Paraffin: PNKD Antibody [NBP1-88348] - Staining of human kidney shows cytoplasmic positivity in renal tubules. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 16 Days
$293.00
Details
Mouse Rabbit Un-conjugated WB Western Blot: PNKD Antibody [NBP1-74205] - Mouse Heart lysate, concentration 1 ug/ml. 100 μL Log in to see 8 to 11 Days
$488.73
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using PNKD antibody. 200 μL Log in to see 12 to 14 Days
$438.90
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μL Log in to see 11 to 14 Days
$390.50
Details

Top referenced anti-PNKD Antibodies

  1. Human Polyclonal PNKD Primary Antibody for ICC, IF - ABIN4346528 : Guo, Dong, Ji, Wu: Myofibrillogenesis regulator-1 overexpression is associated with poor prognosis of gastric cancer patients. in World journal of gastroenterology 2012 (PubMed)

  2. Human Polyclonal PNKD Primary Antibody for ICC, IF - ABIN4346527 : Sadegh, Ekman, Krawczyk, Svensson, Göransson, Dahan, Nilsson, Albinsson, Uvelius, Swärd: Detrusor induction of miR-132/212 following bladder outlet obstruction: association with MeCP2 repression and cell viability. in PLoS ONE 2015 (PubMed)

More Antibodies against PNKD Interaction Partners

Human Paroxysmal Nonkinesigenic Dyskinesia (PNKD) interaction partners

  1. The short isoform of the myofibrillogenesis regulator 1 (MR-1S) as a new COX assembly factor, which works with the highly conserved PET100 and PET117 chaperones to assist COX biogenesis in higher eukaryotes.

  2. The combined analysis identified a new risk association for colorectal cancer (CRC) at 2q35 marked by rs992157 which is intronic to PNKD and TMBIM1.Intriguingly this susceptibility single-nucleotide polymorphism (SNP) is in strong linkage disequilibrium (r(2) = 0.90, D' = 0.96) with the previously discovered GWAS SNP rs2382817 for inflammatory bowel disease (IBD).

  3. study highlights the frequency, novel mutations and clinical and molecular spectrum of PRRT2, SLC2A1 and PNKD mutations as well as the phenotype-genotype overlap among these paroxysmal movement disorders.

  4. This study present the pedigree is the first PNKD family from Chinese Mainland, which is also the largest PNKD family among those reported across the globe. It included 5 generations and 26 patients.

  5. MR-1 functions as a tumor promoter in MCF7 cells by activating the MEK/ERK signaling

  6. MR-1 overexpression was tightly associated with more aggressive tumor behavior and a poor prognosis in pancreatic ductal adenocarcinoma.

  7. MR-1 was up-regulated in gastric cancer tissues. High expression of MR-1 in gastric cancer was significantly correlated with clinical stage. Postoperative survival of the MR-1 positive group tended to be poorer than that of the MR-1 negative group.

  8. A Taiwanese family with paroxysmal nonkinesigenic dyskinesia has a heterozygous c.20 C>T (p.Ala7Val) mutation which was clearly segregated in the five affected patients.

  9. MR-1S is highly expressed in ovarian cancer cells and tissues.

  10. In this report we present two families with paroxysmal non-kinesigenic dyskinesia of Southern European origin carrying a PNKD protein recurrent mutation.

  11. Mutations in PNKD causing paroxysmal dyskinesia alters protein cleavage and stability.

  12. The pnkd mutation alters such a response, suggesting that a less flexible AC region may be more effective in coupling Ca(2+) binding to channel opening.

  13. MR-1 is a novel myofibrillogenesis regulator in human muscle

  14. Different missense mutations in exon 1 of MR1 that cosegregate with PNKD were identified in each multiplex family. These single-nucleotide mutations predicted substitution of valine for alanine in residue 7 in one family and residue 9 in the other.

  15. autosomal dominant paroxysmal nonkinesigenic dyskinesia seems to be a homogenous disorder, for which the MR-1 gene is the major disease gene.

  16. The Serbian family further demonstrates that recurrent MR-1 mutations are associated with paroxysmal nonkinesigenic dyskinesia.

  17. Following down-regulation of MR-1, the phosphorylations of MLC2, focal adhesion kinase (FAK), and Akt were dramatically decreased

  18. Our family was 1 of 8 families originally reported in which a mutation in the myofibrillogenesis regulator 1 (MR-1) gene caused the paroxysmal non-kinesigenic dyskinesia phenotype

PNKD Antigen Profile

Protein Summary

This gene is thought to play a role in the regulation of myofibrillogenesis. Mutations in this gene have been associated with the movement disorder paroxysmal non-kinesigenic dyskinesia. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PNKD

  • paroxysmal nonkinesigenic dyskinesia (PNKD) antibody
  • paroxysmal nonkinesiogenic dyskinesia (Pnkd) antibody
  • 2210013N15Rik antibody
  • 2810403H05Rik antibody
  • AI854243 antibody
  • Brp17 antibody
  • DYT8 antibody
  • FPD1 antibody
  • KIPP1184 antibody
  • MNCb-5687 antibody
  • MR-1 antibody
  • MR1 antibody
  • PDC antibody
  • PKND1 antibody
  • Tahccp2 antibody

Protein level used designations for PNKD

brain protein 17 , myofibrillogenesis regulator 1 , probable hydrolase PNKD , trans-activated by hepatitis C virus core protein 2 , paroxysmal nonkinesiogenic dyskinesia , paroxysmal nonkinesiogenic dyskinesia protein

GENE ID SPECIES
25953 Homo sapiens
616561 Bos taurus
56695 Mus musculus
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