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anti-Paternally Expressed 10 (PEG10) Antibodies

This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. Additionally we are shipping Paternally Expressed 10 Kits (9) and Paternally Expressed 10 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PEG10 23089 Q86TG7
PEG10 170676 Q7TN75
PEG10 102553587  
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Top anti-Paternally Expressed 10 Antibodies at antibodies-online.com

Showing 10 out of 111 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: PEG10 Sample Type: Lung Tumor lysates Antibody Dilution: 1.0ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: PEG10 Sample Type: Thyroid Tumor lysates Antibody Dilution: 1.0ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, ICC, IHC, WB Figure 1: Western blot analysis using PEG10 mouse mAb against truncated Trx-PEG10 recombinant protein (1),truncated GST-PEG10 (aa1-120) recombinant protein (2) and full-length PEG10 (aa1-325)-hIgGFc transfected CHO-K1 cell lysate (3). Dilution: 1/500 - 1/2000 Figure 2: Immunohistochemical analysis of paraffin-embedded human Placenta tissues using PEG10 mouse mAb Dilution: 1/200 - 1/1000 100 μL Log in to see 10 to 11 Days
$561.00
Details
Human Rabbit Un-conjugated FACS, WB PEG10 Antibody (N-term) (ABIN656590) western blot analysis in U251 cell line lysates (35 µg/lane). This demonstrates the PEG10 antibody detected the PEG10 protein (arrow). 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated EIA, FACS, WB Flow cytometric analysis of U251 cells using PEG10 Antibody (N-term) Cat.-No AP53253PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Western blot analysis of PEG10 Antibody (N-term) in U251 cell line lysates (35ug/lane). This demonstrates the PEG10 antibody detected the PEG10 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated ICC, IF, IHC (p), IHC, ELISA, WB Immunohistochemistry-Paraffin: PEG10 Antibody (1B1C4) [NBP1-28875] - Immunohistochemical analysis of paraffin-embedded human Placenta tissues using PEG10 mouse mAb Western Blot: PEG10 Antibody (1B1C4) [NBP1-28875] - Analysis using PEG10 monoclonal antibody against truncated Trx-PEG10 recombinant protein(1),truncated GST-PEG10(aa1-120) recombinant protein(2) and full-length PEG10(aa1-325)-hIgGFc transfected CHO-K1 cell lysate(3). . 0.1 mL Log in to see 7 to 9 Days
$514.63
Details
Human Mouse Un-conjugated ELISA, IF/ICC, IHC, WB 100 μL Log in to see 11 to 16 Days
$426.40
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: PEG10 Antibody [NBP2-13749] - Staining of human placenta shows strong cytoplasmic positivity in a subset of trophoblastic cells. Immunocytochemistry/Immunofluorescence: PEG10 Antibody [NBP2-13749] - Staining of human cell line Hep G2 shows positivity in nucleus & cytoplasm. Antibody staining is shown in green. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Mouse Un-conjugated ELISA, IF, IHC, IHC (p), WB Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-PEG10 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200. 50 μL Log in to see 11 to 14 Days
$484.00
Details
Human Mouse Un-conjugated IHC, ELISA, WB 100 μL Log in to see 11 to 16 Days
$426.40
Details

Top referenced anti-Paternally Expressed 10 Antibodies

  1. Human Monoclonal PEG10 Primary Antibody for IHC, ELISA - ABIN969349 : Jie, Lang, Jian, Chaoqun, Dehua, Yi, Yanping, Luokun, Qiuping, Hui, Feili, Boquan, Youxin, Jinquan: Androgen activates PEG10 to promote carcinogenesis in hepatic cancer cells. in Oncogene 2007 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal PEG10 Primary Antibody for ICC, IHC - ABIN969348 : Kochetov, Ahmad, Ivanisenko, Volkova, Kolchanov, Sarai: uORFs, reinitiation and alternative translation start sites in human mRNAs. in FEBS letters 2008 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal PEG10 Primary Antibody for ELISA, IHC (p) - ABIN5585534 : Shyu, Lee, Lu, Chen, Chien, Chen, Lin, Tsou, Chen, Hsieh, Huang: miR-122-mediated translational repression of PEG10 and its suppression in human hepatocellular carcinoma. in Journal of translational medicine 2016 (PubMed)

  4. Human Monoclonal PEG10 Primary Antibody for ICC, IF - ABIN449947 : Peng, Zhu, Yin, Zhang, Wei, Liu, Liu, Gao, Jiang, Miao: PEG10 overexpression induced by E2F-1 promotes cell proliferation, migration, and invasion in pancreatic cancer. in Journal of experimental & clinical cancer research : CR 2017 (PubMed)

More Antibodies against Paternally Expressed 10 Interaction Partners

Human Paternally Expressed 10 (PEG10) interaction partners

  1. Results demonstrated that an increased expression of PEG10 is associated vessel invasion, and the overall survival time of PC patients. E2F-1 (show E2F1 Antibodies) mediated PEG10 overexpression promotes pancreatic cancer (PC) cell proliferation via accelerating cell cycle progression and increase migration and invasion through ERK (show EPHB2 Antibodies)/MMP7 (show MMP7 Antibodies) pathway. These results suggest that PEG10 may serve as an oncogene (show RAB1A Antibodies) in PC pathogenesis.

  2. miR (show MLXIP Antibodies)-122 suppresses PEG10 expression via direct binding to the 3'-UTR (show UTS2R Antibodies) of the PEG10 transcript.

  3. PEG10 expression associates with the lymph node metastasis and overall survival of hepatocellular carcinoma patients.PEG10 expression level is essential for TGF-beta1 (show TGFB1 Antibodies) induced epithelialmesenchymal transition.

  4. Knockdown of PEG10 expression by siRNA could lead to growth arrest and cell apoptosis in diffuse large B cell lymphoma cells in vitro.

  5. PEG10 protein could be a potential biomarker predicting early recurrence and recurrence-free survival in HCC (show FAM126A Antibodies) patients after curative resection, even in those with normal serum alpha-fetoprotein (show AFP Antibodies) levels.

  6. Study shows that expression level of PEG10 was significantly elevated in breast cancer tissues and associated with distant metastasis and poor clinical outcome and provides evidence that PEG10 is a crucial oncogene (show RAB1A Antibodies).

  7. important role in trophoblast proliferation and promotes trophoblast invasion through TIMP-1 (show TIMP1 Antibodies)

  8. Results revealed that PEG10 high expression was closely associated with the TNM (show ODZ1 Antibodies) classification in lung cancer and is a critical indicator for poor prognosis. Also, It promotes significantly proliferation, migration and invasion of A549 lung cancer cells.

  9. The downregulated expression of the imprinted gene PEG10 may be an important reason for the occurrence of preeclampsia.

  10. elevated expression of PEG10 is likely to be involved in the pathophysiology of preeclampsia

Mouse (Murine) Paternally Expressed 10 (PEG10) interaction partners

  1. Loss of DNA methylation (show HELLS Antibodies) at the Peg10 imprinted gDMD associated with decreased embryonic viability and decreased labyrinthine volume.

  2. Knockdown of Syncytin-A (show ERVW-1 Antibodies) demonstrated a functional regulation of cell-cell fusion, where knockdown of Peg10 showed no involvement in cell fusion

  3. Programmed -1 ribosomal frameshifting in mouse and human Peg10 genes.

  4. Peg10 gene is imprinted, with preferential expression from the paternal allele, and its deletion results in early embryonic lethality.

  5. Results indicate that the induction of the imprinted gene paternally expressed 10 (PEG10) may play an important role during liver regeneration or carcinogenesis of the hepatocyte.

  6. These findings strongly indicate that peg10 plays a crucial role at the immediate early (show JUN Antibodies) stage of adipocyte differentiation.

  7. the ORF1 (show MED14 Antibodies)-2 protein of PEG10, synthesized utilizing the most efficient -1 frameshift mechanism yet documented in vivo, will have an essential function that is intrinsic to the importance of PEG10 in mammals

Cow (Bovine) Paternally Expressed 10 (PEG10) interaction partners

  1. the abnormal DNA methylation (show HELLS Antibodies) epigenetic reprogramming of imprinting PEG10 gene in placenta may be one of the main causes of the abnormal development and death of the transgenic cloned cattle.

Pig (Porcine) Paternally Expressed 10 (PEG10) interaction partners

  1. polymorphisms in PEG10 and PPP1R9A (show PPP1R9A Antibodies) were associated with fat deposition and carcass traits

  2. The imprinting status of PEG10 is conserved in swine as paternal expression was demonstrated by quantitative allelic sequencing of reciprocal crosses in fetal tissues of whole brain, carcass, liver and placentae.

  3. The expression patterns of PLAGL1 (show PLAGL1 Antibodies) and PEG10 genes in two breeds of swine are reported.

Paternally Expressed 10 (PEG10) Antigen Profile

Protein Summary

This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.

Gene names and symbols associated with PEG10

  • paternally expressed 10 (PEG10) antibody
  • paternally expressed 10 (Peg10) antibody
  • AA407948 antibody
  • Edr antibody
  • HB-1 antibody
  • Mar2 antibody
  • Mart2 antibody
  • MEF3L antibody
  • MyEF-3 antibody
  • RGAG3 antibody

Protein level used designations for PEG10

MEF3 like 1 , MEF3-like protein 1 , embryonal carcinoma differentiation regulated , embryonal carcinoma differentiation-regulated protein , mammalian retrotransposon-derived protein 2 , myelin expression factor 3-like protein 1 , paternally expressed gene 10 protein , retrotransposon gag domain containing 3 , retrotransposon gag domain-containing protein 3 , retrotransposon-derived gag-like polyprotein , retrotransposon-derived protein PEG10 , ty3/Gypsy-like protein , MyEF-3 like , embryonal carcinoma differentiation regulated protein , myelin expression factor 3 , paternally expressed 10 , LOW QUALITY PROTEIN: retrotransposon-derived protein PEG10 , retrotransposon-derived protein PEG10-like

GENE ID SPECIES
23089 Homo sapiens
170676 Mus musculus
472446 Pan troglodytes
482307 Canis lupus familiaris
618138 Bos taurus
654416 Sus scrofa
700853 Macaca mulatta
100062501 Equus caballus
100359412 Ovis aries
102553587 Rattus norvegicus
100352080 Oryctolagus cuniculus
100720271 Cavia porcellus
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