anti-Peptidyl Arginine Deiminase, Type II Antibodies

Protein Summary

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.

Gene names and symbols associated with PADI2

• peptidyl arginine deiminase 2 (PADI2) antibody
• peptidyl arginine deiminase, type II (padi2) antibody
• protein-arginine deiminase type-2 (LOC100357368) antibody
• peptidyl arginine deiminase, type II S homeolog (padi2.S) antibody
• peptidyl arginine deiminase, type II (PADI2) antibody
• Show all gene names
• peptidyl arginine deiminase, type II (Padi2) antibody
• peptidyl arginine deiminase 2 (Padi2) antibody

• mKIAA0994 antibody
• PAD-H19 antibody
• PAD2 antibody
• PADI2 antibody
• Pdi antibody
• Show all synonym aliases
• Pdi2 antibody

Protein level used designations for PADI2

peptidyl arginine deiminase, type II , protein-arginine deiminase type-2-like , peptidlyarginine deiminase type II , peptidylarginine deiminase II , protein arginine deiminase , protein-arginine deiminase type II , protein-arginine deiminase type-2 , peptidyl arginine deiminase, type 2 , PAD type II , peptidyl arginine deiminase, type II; PAD type II