anti-Peptidyl Arginine Deiminase, Type IV (PADI4) Antibodies

PADI4 is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. Additionally we are shipping PADI4 Kits (20) and PADI4 Proteins (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PADI4 23569 Q9UM07
PADI4 18602 Q9Z183
PADI4 29512 O88807
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Top anti-PADI4 Antibodies at antibodies-online.com

Showing 10 out of 118 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: PADI4 Sample Type: 721_B Cell lysates Antibody Dilution: 1.0ug/ml  There is BioGPS gene expression data showing that PADI4 is expressed in 721_B 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, IF, IHC, IHC (p), WB 100 μL Log in to see 7 to 9 Days
$522.50
Details
Human Mouse Un-conjugated IHC, IHC (p), WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Human Rabbit Un-conjugated WB Western blot analysis of anti-PAD4 Pab (ABIN389125) in 293 cell line lysate. PAD4(arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Goat Un-conjugated ELISA, WB ABIN185308 (0.3µg/ml) staining of human spleen lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$358.02
Details
Human Mouse Un-conjugated IF, IHC, IHC (p), WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Human Mouse Un-conjugated FACS, WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Human Rabbit Un-conjugated IF, IHC, WB 100 μL Log in to see 16 Days
$334.02
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details

Top referenced anti-PADI4 Antibodies

  1. Human Polyclonal PADI4 Primary Antibody for ELISA, WB - ABIN250318 : Wang, Wysocka, Sayegh, Lee, Perlin, Leonelli, Sonbuchner, McDonald, Cook, Dou, Roeder, Clarke, Stallcup, Allis, Coonrod: Human PAD4 regulates histone arginine methylation levels via demethylimination. in Science (New York, N.Y.) 2004 (PubMed)
    Show all 2 Pubmed References

  2. Cow (Bovine) Polyclonal PADI4 Primary Antibody for WB - ABIN2785937 : Costenbader, Chang, De Vivo, Plenge, Karlson: Genetic polymorphisms in PTPN22, PADI-4, and CTLA-4 and risk for rheumatoid arthritis in two longitudinal cohort studies: evidence of gene-environment interactions with heavy cigarette smoking. in Arthritis research & therapy 2008 (PubMed)

More Antibodies against PADI4 Interaction Partners

Human Peptidyl Arginine Deiminase, Type IV (PADI4) interaction partners

  1. PADI4 may be closely associated with hypoxiainduced autophagy, and the inhibition of hypoxiainduced autophagy by PADI4 knockdown may contribute to an increase in the apoptosis of RAFLS.

  2. MiRNA-146a rs2910164 and IRAK1 (show IRAK1 Antibodies) rs3027898 polymorphisms were a risk factor for predisposition to Rheumatoid Arthritis in Egyptian Population in codominant and dominant tested inheritance models, while, the miRNA-499 rs3746444 and PADI4 rs1748033 polymorphisms were a risk factor in codominant and recessive one.

  3. Meta-analysis indicated a significantly increased association between PADI -104C/T polymorphism and rheumatoid arthritis (RA) in Chinese and Japanese populations (which were the majority of included populations in the analysis).

  4. PADI4 interacted with SYVN1 (show SYVN1 Antibodies) directly and that overexpression of PADI4 suppressed the ubiquitination of proteins. Thus, a reduction in ER stress induced by PADI4 may abrogate the initiation of chronic RA by suppressing the proliferative signals of RA synoviocytes.

  5. mRNA expression of PADI2 (show PADI2 Antibodies), PADI4 and Sp1 (show PSG1 Antibodies) is upregulated in rheumatoid arthritis bone marrow CD34 (show CD34 Antibodies)+ cells independently of the systemic inflammation or treatment regimen.

  6. this study in a Southern Mexican population suggests that PADI4 individual polymorphisms and the related susceptibility haplotype (GTG (show GGT1 Antibodies)) are also genetic risk markers for rheumatoid arthritis

  7. The T allele of PADI4 rs2240340 is associated with Rheumatoid Arthritis in Asians.

  8. PADI4 contributes to gastric tumorigenesis by upregulating CXCR2 (show CXCR2 Antibodies), KRT14 (show KRT14 Antibodies) and TNF-alpha (show TNF Antibodies) expression.

  9. In this case-control study with sufficient sample size to detect associations, we observed that PADI4 SNPS rs11203367 and rs874881 do not significantly determine RA susceptibility

  10. SNPs of PADI4 may be a risk factor for airway abnormalities in RA.

Mouse (Murine) Peptidyl Arginine Deiminase, Type IV (PADI4) interaction partners

  1. PADi4 is critical for neutrophil extracellular traps formation, but is dispensable for generalized citrullination

  2. sFlt-1 overexpression in Padi4(-/-) mice resulted in dramatically lower inflammatory and thrombotic response, which was accompanied by significant reduction in pregnancy losses. Inhibition of NETosis may serve as a novel target in disorders of impaired placentation.

  3. a role for NETs in cardiac fibrosis and conclude that PAD4 regulates age-related organ fibrosis and dysfunction.

  4. PADI4 exacerbates arthritis with diverse immunological modifications.

  5. Selective inhibition of peptidylarginine deiminase IV with Cl-amidine blocked NET formation, reduced atherosclerotic lesion area, and delayed time to carotid artery thrombosis in a photochemical injury model.

  6. Padi4 is part of the pluripotency transcriptional network, binding to regulatory elements of key stem-cell genes and activating their expression

  7. PAD4 regulates the proliferation of multipotent progenitors in the bone marrow by controlling c-myc (show MYC Antibodies) expression.

  8. PAD4-mediated chromatin decondensation in the neutrophil is crucial for pathological venous thrombosis and present neutrophil activation and PAD4 as potential drug targets for deep vein thrombosis.

  9. PAD4 is dispensable in this effector phase model of arthritis

  10. analysis of regulation of histone modification and chromatin structure by the p53 (show TP53 Antibodies)-PADI4 pathway

PADI4 Antigen Profile

Protein Summary

This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response.

Gene names and symbols associated with PADI4

  • peptidyl arginine deiminase 4 (PADI4) antibody
  • peptidyl arginine deiminase, type IV (Padi4) antibody
  • peptidyl arginine deiminase 4 (Padi4) antibody
  • PAD antibody
  • Pad4 antibody
  • PADI5 antibody
  • Pdi4 antibody
  • PDI5 antibody

Protein level used designations for PADI4

peptidyl arginine deiminase, type IV , protein-arginine deiminase type-4-like , HL-60 PAD , PADI-H protein , peptidyl arginine deiminase, type V , protein-arginine deiminase type IV , protein-arginine deiminase type-4 , PAD type IV , peptidylarginine deiminase IV , PAD-R4 , peptidyl arginine deiminase, type 4 , peptidylarginine deiminase type alpha

GENE ID SPECIES
100026011 Monodelphis domestica
100049826 Equus caballus
100415489 Callithrix jacchus
100471129 Ailuropoda melanoleuca
100592291 Nomascus leucogenys
23569 Homo sapiens
18602 Mus musculus
456530 Pan troglodytes
29512 Rattus norvegicus
606921 Canis lupus familiaris
508161 Bos taurus
100524749 Sus scrofa
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