anti-Peripherin (PRPH) Antibodies

PRPH encodes a cytoskeletal protein found in neurons of the peripheral nervous system. Additionally we are shipping Peripherin Kits (15) and Peripherin Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PRPH 5630 P41219
PRPH 19132  
PRPH 24688  
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Top anti-Peripherin Antibodies at antibodies-online.com

Showing 10 out of 156 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PRPH Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human heart 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PRPH Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of Peripherin expression in HeLa (A) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HepG2 cells, using Peripherin Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Peripherin Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, WB ABIN6266623 at 1/100 staining human colon carcinoma tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of Peripherin expression in Mouse brain lysate 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE Peripherin antibody antibody diluted at 1:1000 100 μL 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB Anti-PRPH / Peripherin antibody IHC staining of human nerve. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1103819 concentration 10 ug/ml. 50 μL 11 to 14 Days
$484.00
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Rat Goat Un-conjugated ELISA, WB   100 μg 6 to 7 Days
$429.84
Details

Top referenced anti-Peripherin Antibodies

  1. Human Polyclonal Peripherin Primary Antibody for ICC, IHC (fro) - ABIN152483 : Burgess, Jucius, Ackerman: Motor axon guidance of the mammalian trochlear and phrenic nerves: dependence on the netrin receptor Unc5c and modifier loci. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 (PubMed)
    Show all 5 Pubmed References

  2. Polyclonal Peripherin Primary Antibody for IHC (fro), IF - ABIN540386 : Arvanian, Bowers, Petruska, Motin, Manuzon, Narrow, Federoff, Mendell: Viral delivery of NR2D subunits reduces Mg2+ block of NMDA receptor and restores NT-3-induced potentiation of AMPA-kainate responses in maturing rat motoneurons. in Journal of neurophysiology 2004 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal Peripherin Primary Antibody for IHC, ELISA - ABIN1533379 : Sekino, Nakano, Hamaue, Chuganji, Sakamoto, Yoshimura, Origuchi, Okita: Sensory hyperinnervation and increase in NGF, TRPV1 and P2X3 expression in the epidermis following cast immobilization in rats. in European journal of pain (London, England) 2014 (PubMed)

  4. Human Monoclonal Peripherin Primary Antibody for ICC, IF - ABIN152484 : Errante, Wiche, Shaw: Distribution of plectin, an intermediate filament-associated protein, in the adult rat central nervous system. in Journal of neuroscience research 1994 (PubMed)

More Antibodies against Peripherin Interaction Partners

Human Peripherin (PRPH) interaction partners

  1. Genome-wide association study of sural nerve conduction amplitude and velocity in 7045 Icelanders and find a low-frequency splice-donor variant in PRPH associated with reduced amplitude of the sural nerve action potential, but not with sural nerve conduction velocity.

  2. Desmin, Glial Fibrillary Acidic Protein, Vimentin, and Peripherin are type III intermediate filaments that have roles in health and disease [review]

  3. To discover of Phosphorylated autoantigens Peripherin as a Major Humoral Autoantigen in Type 1 Diabetes Mellitus.

  4. In patients with HD, a panel using calretinin and peripherin with or without MAP-2 may be most helpful in identifying transition zones

  5. interaction between disease-causing RAB7A mutants and peripherin could play an important role in Charcot-Marie-Tooth type 2B neuropathy

  6. A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration.

  7. This work contributes to determine the role of PRPH gene variants in ALS. Further studies are necessary to define the mechanisms through which the mutant peripherin could cause ALS phenotype.

  8. study analyzed expression of peripherin(PP) in the cochlea; in organ of Corti, PP seems to be specifically expressed in outer hair cell afferents; small or type II spiral ganglion cell bodies also intensely express PP

  9. although the mechanisms underlying peripherin co-localization in Bunina bodies are unknown, peripherin could be involved in forming these inclusions

  10. Transgenic peripherin isoform expression reveals post-transcriptional changes to the normal expression pattern associated with malformed filaments and intracellular inclusions underlying a role in the pathogenesis of amyotrophic lateral sclerosis.

  11. The data of this experiment document the expression of peripherin in Lewy body-like inclusions , which may provide a clue to the pathogenesis of neurodegeneration in ALS.

  12. Peripherin overexpression in transgenic mice can cause defective transport of type IV neurofilament proteins, a phenomenon that may account for the progressive formation of amyotrophic lateral sclerosis-like spheroids in axons.

  13. peripherin is a novel substrate for Akt in vivo and its phosphorylation may play a role in motor nerve regeneration

  14. Peripherin splicing abnormalities occur in amyotrophic lateral sclerosis generating aggregation-prone splice isoforms, one of which causes peripherin aggregation when its expression is upregulated.

  15. PKCepsilon through its interaction with peripherin facilitates its aggregation and subsequent cell death

  16. Expression of the 2 markers, peripherin and alpha-internexin, in a small round cell tumor strongly favors the diagnosis of neuroblastoma.

  17. Transgenic mice expressing the PRPH-EGFP genomic reporter display intrinsic peripheral nervous system fluorescence.

Mouse (Murine) Peripherin (PRPH) interaction partners

  1. Data suggest that the underlying molecular mechanisms in amyotrophic lateral sclerosis pathogenesis involve peripherin mis-splicing and altered homeostasis of nerve fibers.

  2. Contralateral and ipsilateral olivocochlear efferent-mediated suppression of the cochlear amplifier were absent in Prph null mice.

  3. Data suggest anti-peripherin (PRPH) B cells represent a heterogeneous population that is generated early in life but proliferates as diabetes is established.

  4. peripherin appears to be a participant in learning and memory impairment in mice

  5. rather than forming an independent structure, peripherin is a subunit of neurofilaments in the adult peripheral nervous system

  6. Peripherin isoform expression and inclusion formation serve a physiologically relevant role in the pathology of amyotrophic lateral sclerosis.

  7. Complex post-transcriptional processes may underlie the continuum between peripherin-mediated neuronal repair and its pathogenic role in a transgenic model of amyotrophic lateral sclerosis.

  8. Peripherin may interact with other cytoskeletal elements to regulate outgrowth of the peripheral neurites of type II SGN, distinguishing these neurons from the type I SGN innervating the inner hair cells.

  9. peripherin gene sequences direct Cre recombinase expression to peripheral neurons in transgenic mice.

  10. Overexpression of peripherin in mice deficient for neurofilament light (NF-L) subunits induced a progressive ALS-like spinal motor neuron degeneration prevented by simultaneous overexpression of NF-H

  11. Of the three peripherin isoforms, Per 61 was neurotoxic, being assembly incompetent and inducing degeneration of cultured motor neurons. Per 61 was detected in motor neurons of SOD1G37R transgenic mice but not of control or peripherin transgenic mice.

  12. Peripherin is not a key contributor of motor neuron degeneration associated with toxicity of mutant superoxide dismutase 1.

  13. In the hippocampus of Per mice, the levels of MAP2 were decreased, though synaptophysin and PSD95 remained unchanged. These intriguing findings suggest a role of peripherin in the alteration of hippocampal synaptic plasticity.

  14. mutations in peripherin/rds have roles in retinal diseases [review]

  15. Mouse models on genetic macular degeneration include studies on Prph.

  16. Peripherin is a major autoantigen targeted during development of type 1 diabetes mellitus; peripherin-specific B lymphocytes are mainly attracted to the islet during disease.

  17. In the adult mouse hindbrain, peripherin is expressed in discrete neuronal subpopulations that have sensory, motor and autonomic functions.

  18. Genetic supplementation of Prph alleviates a loss-of-function phenotype in C214S model of retinitis pigmentosa.

  19. Per-45 isophorm is required for normal network formation, with the absence of Per-45 leading to irregular filamentous structures

  20. Peripherin is expressed in the tuberomammillary neurons of the mouse hypothalamus.The complete overlap between histidine decarboxylase and peripherin renders peripherin a useful new marker for histaminergic neurons in the hypothalamus.

Peripherin (PRPH) Antigen Profile

Protein Summary

This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility to amyotrophic lateral sclerosis.

Gene names and symbols associated with anti-Peripherin (PRPH) Antibodies

  • peripherin (PRPH) antibody
  • peripherin (Prph) antibody
  • peripherin (prph) antibody
  • peripherin L homeolog (prph.L) antibody
  • if3 antibody
  • MGC69454 antibody
  • nef4 antibody
  • Perf antibody
  • plasticin antibody
  • prph1 antibody
  • zgc:111926 antibody

Protein level used designations for anti-Peripherin (PRPH) Antibodies

neurofilament 4 (57kD) , peripherin 1 , peripherin , neuronal intermediate filament IF3

GENE ID SPECIES
5630 Homo sapiens
19132 Mus musculus
24688 Rattus norvegicus
407916 Xenopus (Silurana) tropicalis
477618 Canis lupus familiaris
510082 Bos taurus
100059208 Equus caballus
100152434 Sus scrofa
380221 Xenopus laevis
100357822 Oryctolagus cuniculus
101082247 Felis catus
100726499 Cavia porcellus
30259 Danio rerio
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