anti-Peripherin (PRPH) Antibodies

PRPH encodes a cytoskeletal protein found in neurons of the peripheral nervous system. Additionally we are shipping Peripherin Kits (15) and Peripherin Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PRPH 5630 P41219
PRPH 19132  
PRPH 24688  
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Top anti-Peripherin Antibodies at antibodies-online.com

Showing 10 out of 142 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IHC (fro), IF, IHC (p), IHC, ELISA, WB Detection of the 57 kDa peripherin protein in whole rat brain stem homogenate using ABIN152483 (1:20,000).  The faint 48 kDa band is a peripherin molecule. Immunocytochemistry/Immunofluorescence: Peripherin Antibody  - Mixed neuron/glia cultures from newborn rat brain stained with  antibody to peripherin (green) and chicken polyclonal antibody to phosphorylated NF-H (red channel). A class of large neurons, like the one at the top right of this image, contain peripherin, while the majority of neurons and their processes contain NF-H and not peripherin. The blue channel reveals the localization of DNA. 0.1 mL Log in to see 7 to 9 Days
$485.88
Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-PRPH Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-PRPH Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of Peripherin expression in HeLa (A) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HepG2 cells, using Peripherin Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Peripherin Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE Peripherin antibody antibody diluted at 1:1000 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Mouse Un-conjugated ICC, IF, ELISA, WB Immunocytochemistry/Immunofluorescence: Peripherin Antibody (8G2)  - Analysis of human neuroblastoma cell line SH-SY5Y (A) and rat pheochromocytoma cell line PC12 (B), stained with mouse mAb to peripherin, , dilution 1:500, in red, and costained with chicken pAb to vimentin, dilution 1:10,000, in green. The blue is DAPI staining of nuclear DNA. Peripherin, one of the Class III family of intermediate filament (IF) subunit proteins is revealed by  antibody in the perinuclear region in some SH-SY5Y cells and in all PC12 cells. Vimentin, a protein also in the Class III IF family, is detected in a subpopulation of SH-SY5Y cells which are negative for peripherin. PC12 cells express peripherin but not vimentin. Western Blot: Peripherin Antibody (8G2)  - Analysis of tissue and cell lysates probed with mouse mAb to peripherin, , dilution 1:500 in green:  protein standard (red),  mouse spinal cord,  rat spinal cord,  cow spinal cord,  SH-SY5Y cells, and  PC12 cells. The band at ~57kDa corresponds to the peripherin protein. Bands at 50 and 25kDa detected in the mouse spinal cord lysate, correspond to the heavy and light chains of mouse IgG. 0.5 mL Log in to see 7 to 9 Days
$415.44
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB Anti-PRPH / Peripherin antibody IHC staining of human nerve. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1103819 concentration 10 ug/ml. 50 μL Log in to see 7 to 9 Days
$484.00
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details

PRPH Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , ,
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Mouse (Murine) , ,
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Rat (Rattus) , ,
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Top referenced anti-Peripherin Antibodies

  1. Human Polyclonal Peripherin Primary Antibody for ICC, IHC (fro) - ABIN152483 : Burgess, Jucius, Ackerman: Motor axon guidance of the mammalian trochlear and phrenic nerves: dependence on the netrin receptor Unc5c and modifier loci. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 (PubMed)
    Show all 5 Pubmed References

  2. Polyclonal Peripherin Primary Antibody for IHC (fro), IF - ABIN540386 : Arvanian, Bowers, Petruska, Motin, Manuzon, Narrow, Federoff, Mendell: Viral delivery of NR2D subunits reduces Mg2+ block of NMDA receptor and restores NT-3-induced potentiation of AMPA-kainate responses in maturing rat motoneurons. in Journal of neurophysiology 2004 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal Peripherin Primary Antibody for IHC, ELISA - ABIN1533379 : Sekino, Nakano, Hamaue, Chuganji, Sakamoto, Yoshimura, Origuchi, Okita: Sensory hyperinnervation and increase in NGF, TRPV1 and P2X3 expression in the epidermis following cast immobilization in rats. in European journal of pain (London, England) 2014 (PubMed)

  4. Human Monoclonal Peripherin Primary Antibody for ICC, IF - ABIN152484 : Errante, Wiche, Shaw: Distribution of plectin, an intermediate filament-associated protein, in the adult rat central nervous system. in Journal of neuroscience research 1994 (PubMed)

More Antibodies against Peripherin Interaction Partners

Human Peripherin (PRPH) interaction partners

  1. Desmin (show DES Antibodies), Glial Fibrillary Acidic Protein (show GFAP Antibodies), Vimentin (show VIM Antibodies), and Peripherin are type III intermediate filaments that have roles in health and disease [review]

  2. To discover of Phosphorylated autoantigens Peripherin as a Major Humoral Autoantigen in Type 1 Diabetes Mellitus.

  3. In patients with HD, a panel using calretinin and peripherin with or without MAP-2 may be most helpful in identifying transition zones

  4. interaction between disease-causing RAB7A (show RAB7A Antibodies) mutants and peripherin could play an important role in Charcot-Marie-Tooth type 2B neuropathy

  5. This work contributes to determine the role of PRPH gene variants in ALS. Further studies are necessary to define the mechanisms through which the mutant peripherin could cause ALS phenotype.

  6. study analyzed expression of peripherin(PP) in the cochlea; in organ of Corti, PP seems to be specifically expressed in outer hair cell afferents; small or type II spiral ganglion cell bodies also intensely express PP

  7. although the mechanisms underlying peripherin co-localization in Bunina bodies are unknown, peripherin could be involved in forming these inclusions

  8. Transgenic peripherin isoform expression reveals post-transcriptional changes to the normal expression pattern associated with malformed filaments and intracellular inclusions underlying a role in the pathogenesis of amyotrophic lateral sclerosis.

  9. The data of this experiment document the expression of peripherin in Lewy body-like inclusions , which may provide a clue to the pathogenesis of neurodegeneration in ALS.

  10. Peripherin overexpression in transgenic mice can cause defective transport of type IV neurofilament proteins, a phenomenon that may account for the progressive formation of amyotrophic lateral sclerosis-like spheroids in axons.

Mouse (Murine) Peripherin (PRPH) interaction partners

  1. Data suggest that the underlying molecular mechanisms in amyotrophic lateral sclerosis pathogenesis involve peripherin mis (show AMH Antibodies)-splicing and altered homeostasis of nerve fibers.

  2. Contralateral and ipsilateral olivocochlear efferent-mediated suppression of the cochlear amplifier were absent in Prph null mice.

  3. Data suggest anti-peripherin (PRPH) B cells represent a heterogeneous population that is generated early in life but proliferates as diabetes is established.

  4. peripherin appears to be a participant in learning and memory impairment in mice

  5. rather than forming an independent structure, peripherin is a subunit of neurofilaments in the adult peripheral nervous system

  6. Peripherin isoform expression and inclusion formation serve a physiologically relevant role in the pathology of amyotrophic lateral sclerosis.

  7. Complex post-transcriptional processes may underlie the continuum between peripherin-mediated neuronal repair and its pathogenic role in a transgenic model of amyotrophic lateral sclerosis.

  8. Peripherin may interact with other cytoskeletal elements to regulate outgrowth of the peripheral neurites of type II SGN, distinguishing these neurons from the type I SGN innervating the inner hair cells.

  9. peripherin gene sequences direct Cre recombinase (show RAG1 Antibodies) expression to peripheral neurons in transgenic mice.

  10. Overexpression of peripherin in mice deficient for neurofilament light (NF-L (show NEFL Antibodies)) subunits induced a progressive ALS-like spinal motor neuron degeneration (show CLN8 Antibodies) prevented by simultaneous overexpression of NF-H (show NEFH Antibodies)

Peripherin (PRPH) Antigen Profile

Protein Summary

This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility to amyotrophic lateral sclerosis.

Gene names and symbols associated with anti-Peripherin (PRPH) Antibodies

  • peripherin (PRPH) antibody
  • peripherin (Prph) antibody
  • peripherin (prph) antibody
  • peripherin L homeolog (prph.L) antibody
  • if3 antibody
  • MGC69454 antibody
  • nef4 antibody
  • Perf antibody
  • plasticin antibody
  • prph1 antibody
  • zgc:111926 antibody

Protein level used designations for anti-Peripherin (PRPH) Antibodies

neurofilament 4 (57kD) , peripherin 1 , peripherin , neuronal intermediate filament IF3

GENE ID SPECIES
5630 Homo sapiens
19132 Mus musculus
24688 Rattus norvegicus
407916 Xenopus (Silurana) tropicalis
477618 Canis lupus familiaris
510082 Bos taurus
100059208 Equus caballus
100152434 Sus scrofa
380221 Xenopus laevis
100357822 Oryctolagus cuniculus
101082247 Felis catus
100726499 Cavia porcellus
30259 Danio rerio
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