Peroxisomal Biogenesis Factor 19 Proteins (PEX19)

PEX19 is necessary for early peroxisomal biogenesis. Additionally we are shipping PEX19 Antibodies (105) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PEX19 5824 P40855
PEX19 19298 Q8VCI5
PEX19 289233  
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Top PEX19 Proteins at

Showing 10 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
Escherichia coli (E. coli) Human Un-conjugated 0.1 mg Log in to see 2 to 3 Days
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 18 Days
Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 15 to 18 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
Yeast Chinese Hamster His tag   1 mg Log in to see 60 to 71 Days
Yeast Orang-Utan His tag   1 mg Log in to see 60 to 71 Days

PEX19 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Peroxisomal Biogenesis Factor 19 (PEX19) Interaction Partners

Human Peroxisomal Biogenesis Factor 19 (PEX19) interaction partners

  1. that newly synthesized UBXD8 (show FAF2 Proteins) is post-translationally inserted into discrete ER subdomains by a mechanism requiring cytosolic PEX19 and membrane-integrated PEX3 (show PEX3 Proteins), proteins hitherto exclusively implicated in peroxisome biogenesis

  2. Thus within the cell, PEX3 (show PEX3 Proteins) is stabilized by PEX19 preventing PEX3 (show PEX3 Proteins) aggregation.

  3. PEX19 formed a complex with the peroxisomal tail anchored protein PEX26 (show PEX26 Proteins) in the cytosol and translocated it directly to peroxisomes by a TRC40 (show ASNA1 Proteins)-independent class I pathway.

  4. PEX3 (show PEX3 Proteins)-PEX19 interaction is crucial for de novo formation of peroxisomes in peroxisome-deficient cells.

  5. The crystal structure of the cytosolic domain of PEX3 (show PEX3 Proteins) in complex with a PEX19-derived peptide. PEX3 (show PEX3 Proteins) adopts a novel fold that is best described as a large helical bundle.

  6. a considerable functional diversity of the proteins encoded by two PEX19 splice variants and thereby provide first experimental evidence for specific biological functions of the different predicted domains of the PEX19 protein.

  7. PEX19 binds and stabilizes newly synthesized PMPs in the cytosol, binds to multiple PMP targeting signals (mPTSs), interacts with the hydrophobic domains of PMP targeting signals, and is essential for PMP targeting and import.

  8. Interaction of PEX3 (show PEX3 Proteins) and PEX19 visualized by fluorescence resonance energy transfer (FRET).

  9. Pex19p has a role in assembly of PTS (show PTS Proteins)-receptor docking complexes

  10. Results suggest that PEX3 (show PEX3 Proteins) plays a selective, essential, and direct role in class I peroxisomal membrane protein import as a docking factor for PEX19.

PEX19 Protein Profile

Protein Summary

This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PEX19

  • Peroxin 19 (Pex19)
  • Peroxisomal farnesylated protein (Bm1_19905)
  • peroxisomal biogenesis factor 19 (PEX19)
  • peroxisomal biogenesis factor 19 (Pex19)
  • BEST:GH03076 protein
  • CG5325 protein
  • D1S2223E protein
  • DmelPex19 protein
  • Dmel\\CG5325 protein
  • HK33 protein
  • PBD12A protein
  • Peroxin-19 protein
  • PMP1 protein
  • PMPI protein
  • PxF protein
  • PXMP1 protein

Protein level used designations for PEX19

CG5325-PA , CG5325-PB , Pex19-PA , Pex19-PB , peroxin 19 , peroxisomal farnesylated protein , Peroxisomal farnesylated protein , 33 kDa housekeeping protein , housekeeping gene, 33kD , peroxin-19 , peroxisome biogenesis factor 19

34630 Drosophila melanogaster
6098885 Brugia malayi
5824 Homo sapiens
19298 Mus musculus
289233 Rattus norvegicus
521522 Bos taurus
100689302 Cricetulus griseus
100173241 Pongo abelii
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