Peroxisomal Biogenesis Factor 19 Proteins (PEX19)

PEX19 is necessary for early peroxisomal biogenesis. Additionally we are shipping PEX19 Antibodies (116) and and many more products for this protein.

Gene Name	GeneID	UniProt
PEX19	5824	P40855
PEX19	19298	Q8VCI5
PEX19	289233

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Top PEX19 Proteins at antibodies-online.com

Showing 10 out of 17 products:

Catalog No.	Origin	Source	Conjugate	Quantity	Supplier	Delivery	Price	Details
ABIN3085862	Insect Cells	Human	His tag	1 mg	Log in to see	50 Days	$6,869.04	Details
ABIN3126934	Escherichia coli (E. coli)	Mouse	His tag	1 mg	Log in to see	30 to 35 Days	$5,465.26	Details
ABIN2468999	Escherichia coli (E. coli)	Human	Un-conjugated	0.1 mg	Log in to see	2 to 3 Days	$653.13	Details
ABIN5665360	Escherichia coli (E. coli)	Human	His tag	100 μg	Log in to see	15 to 18 Days	$320.00	Details
ABIN5665361	Escherichia coli (E. coli)	Mouse	His tag	100 μg	Log in to see	15 to 18 Days	$496.00	Details
ABIN2728692	HEK-293 Cells	Human	Myc-DYKDDDDK Tag	20 μg	Log in to see	Available	$814.00	Details
ABIN1314699	Wheat germ	Human	GST tag	10 μg	Log in to see	11 to 12 Days	$414.29	Details
ABIN6119499	Escherichia coli (E. coli)	Human	Un-conjugated	100 μg	Log in to see	11 to 18 Days	$369.55	Details
ABIN6119501	Escherichia coli (E. coli)	Mouse	Un-conjugated	100 μg	Log in to see	11 to 18 Days	$497.47	Details
ABIN667549	Escherichia coli (E. coli)	Human	His tag	100 μg	Log in to see	15 to 19 Days	$400.00	Details

PEX19 Proteins by Origin and Source

Origin	Expressed in	Conjugate
Human	, , ,	, ,
Mouse (Murine)
Rat (Rattus)

More product categories related to PEX19 Protein

More Proteins for Peroxisomal Biogenesis Factor 19 (PEX19) Interaction Partners

Human Peroxisomal Biogenesis Factor 19 (PEX19) interaction partners

that newly synthesized UBXD8 (show FAF2 Proteins) is post-translationally inserted into discrete ER subdomains by a mechanism requiring cytosolic PEX19 and membrane-integrated PEX3 (show PEX3 Proteins), proteins hitherto exclusively implicated in peroxisome biogenesis
Thus within the cell, PEX3 (show PEX3 Proteins) is stabilized by PEX19 preventing PEX3 (show PEX3 Proteins) aggregation.
PEX19 formed a complex with the peroxisomal tail anchored protein PEX26 (show PEX26 Proteins) in the cytosol and translocated it directly to peroxisomes by a TRC40 (show ASNA1 Proteins)-independent class I pathway.
PEX3 (show PEX3 Proteins)-PEX19 interaction is crucial for de novo formation of peroxisomes in peroxisome-deficient cells.
The crystal structure of the cytosolic domain of PEX3 (show PEX3 Proteins) in complex with a PEX19-derived peptide. PEX3 (show PEX3 Proteins) adopts a novel fold that is best described as a large helical bundle.
a considerable functional diversity of the proteins encoded by two PEX19 splice variants and thereby provide first experimental evidence for specific biological functions of the different predicted domains of the PEX19 protein.
PEX19 binds and stabilizes newly synthesized PMPs in the cytosol, binds to multiple PMP targeting signals (mPTSs), interacts with the hydrophobic domains of PMP targeting signals, and is essential for PMP targeting and import.
Interaction of PEX3 (show PEX3 Proteins) and PEX19 visualized by fluorescence resonance energy transfer (FRET).
Pex19p has a role in assembly of PTS (show PTS Proteins)-receptor docking complexes
Results suggest that PEX3 (show PEX3 Proteins) plays a selective, essential, and direct role in class I peroxisomal membrane protein import as a docking factor for PEX19.

PEX19 Protein Profile

Protein Summary

This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PEX19

Peroxin 19 (Pex19)
Peroxisomal farnesylated protein (Bm1_19905)
peroxisomal biogenesis factor 19 (PEX19)
peroxisomal biogenesis factor 19 (Pex19)

BEST:GH03076 protein
CG5325 protein
D1S2223E protein
DmelPex19 protein
Dmel\\CG5325 protein
HK33 protein
PBD12A protein
Peroxin-19 protein
PMP1 protein
PMPI protein
PxF protein
PXMP1 protein

Protein level used designations for PEX19

CG5325-PA , CG5325-PB , Pex19-PA , Pex19-PB , peroxin 19 , peroxisomal farnesylated protein , Peroxisomal farnesylated protein , 33 kDa housekeeping protein , housekeeping gene, 33kD , peroxin-19 , peroxisome biogenesis factor 19

GENE ID	SPECIES
34630	Drosophila melanogaster
6098885	Brugia malayi
5824	Homo sapiens
19298	Mus musculus
289233	Rattus norvegicus
521522	Bos taurus
100689302	Cricetulus griseus
100173241	Pongo abelii

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