Peroxisomal Biogenesis Factor 3 Proteins (PEX3)

The product of PEX3 is involved in peroxisome biosynthesis and integrity. Additionally we are shipping PEX3 Antibodies (23) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PEX3 8504 P56589
PEX3 56535 Q9QXY9
Rat PEX3 PEX3 83519 Q9JJK4
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Top PEX3 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,744.22
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$6,616.87
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,649.05
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,744.22
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Yeast Yeast His tag   1 mg Log in to see 60 to 71 Days
$3,113.00
Details
Yeast Yeast His tag   1 mg Log in to see 60 to 71 Days
$3,175.33
Details

PEX3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for Peroxisomal Biogenesis Factor 3 (PEX3) Interaction Partners

Human Peroxisomal Biogenesis Factor 3 (PEX3) interaction partners

  1. that newly synthesized UBXD8 (show FAF2 Proteins) is post-translationally inserted into discrete ER subdomains by a mechanism requiring cytosolic PEX19 (show PEX19 Proteins) and membrane-integrated PEX3, proteins hitherto exclusively implicated in peroxisome biogenesis

  2. This insertion of PEX3 into the ER is physiologically relevant.

  3. PEX16 (show PEX16 Proteins) mediates the peroxisomal trafficking of two distinct peroxisomal membrane proteins, PEX3 and PMP34 (show SLC25A17 Proteins), via the endoplasmic reticulum

  4. Thus within the cell, PEX3 is stabilized by PEX19 (show PEX19 Proteins) preventing PEX3 aggregation.

  5. Mutations in the PEX19 (show PEX19 Proteins)-binding domain of PEX3 reduce the affinity for PEX19 (show PEX19 Proteins) and destabilize PEX3.

  6. The crystal structure of the cytosolic domain of PEX3 in complex with a PEX19 (show PEX19 Proteins)-derived peptide. PEX3 adopts a novel fold that is best described as a large helical bundle.

  7. Interaction of PEX3 and PEX19 (show PEX19 Proteins) visualized by fluorescence resonance energy transfer (FRET).

  8. Results suggest that PEX3 plays a selective, essential, and direct role in class I peroxisomal membrane protein import as a docking factor for PEX19 (show PEX19 Proteins).

  9. either one or two tryptophan residues of Pex3p (Trp (show TBPL1 Proteins)-104 and Trp (show TBPL1 Proteins)-224) are directly involved in binding to Pex19p.

  10. The cytosolic domain of PEX3, a protein involved in the biogenesis of peroxisomes, binds membrane lipids.

PEX3 Protein Profile

Protein Summary

The product of this gene is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS).

Gene names and symbols associated with PEX3

  • peroxisomal biogenesis factor 3 (LOC692959)
  • peroxisomal biogenesis factor 3 (CpipJ_CPIJ013204)
  • peroxin 3 (pex3)
  • peroxisomal biogenesis factor 3 (PEX3)
  • peroxisomal biogenesis factor 3 (pex3)
  • peroxisomal biogenesis factor 3 L homeolog (pex3.L)
  • peroxisomal biogenesis factor 3 (Pex3)
  • 1700014F15Rik protein
  • 2810027F19Rik protein
  • 2900010N04Rik protein
  • DDBDRAFT_0204086 protein
  • DDBDRAFT_0238047 protein
  • DDB_0204086 protein
  • DDB_0238047 protein
  • PBD10A protein
  • Peroxin-3 protein
  • TRG18 protein
  • zgc:56313 protein

Protein level used designations for PEX3

peroxisomal biogenesis factor 3 , transmembrane protein , peroxin-3 , peroxisomal assembly protein PEX3 , transformation-related protein 18 , Peroxisomal assembly protein PEX3 , peroxisomal assembly protein 3 , Peroxisomal biogenesis factor 3

GENE ID SPECIES
692959 Bombyx mori
6046074 Culex quinquefasciatus
8622947 Dictyostelium discoideum AX4
100230879 Taeniopygia guttata
100582200 Nomascus leucogenys
393197 Danio rerio
444067 Xenopus laevis
421669 Gallus gallus
8504 Homo sapiens
484015 Canis lupus familiaris
515730 Bos taurus
56535 Mus musculus
83519 Rattus norvegicus
100760471 Cricetulus griseus
Selected quality suppliers for PEX3 Proteins (PEX3)
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