Phosphogluconate Dehydrogenase (PGD) ELISA Kits

6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Additionally we are shipping PGD Antibodies (80) and PGD Proteins (19) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
PGD 5226 P52209
PGD 110208 Q9DCD0
PGD 100360180 P85968;
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Top PGD ELISA Kits at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.2 ng/mL 0.78-50 ng/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
$1,026.67
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Rat
  96 Tests Log in to see 15 to 18 Days
$875.60
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Mouse
  96 Tests Log in to see 15 to 18 Days
$875.60
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Pig
  96 Tests Log in to see 15 to 18 Days
$1,029.60
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More ELISA Kits for PGD Interaction Partners

Human Phosphogluconate Dehydrogenase (PGD) interaction partners

  1. identified that 6-phosphogluconate dehydrogenase (6PGD) is critically involved in the development of anaplastic thyroid cancer (ATC (show SRPK1 ELISA Kits)) resistance to doxorubicin. 6PGD inhibition disrupts metabolic reprogramming in doxorubicin-resistant ATC (show SRPK1 ELISA Kits) cells.

  2. Studies indicate link between the 6-phosphogluconate dehydrogenase, oxidative pentose phosphate pathway (PPP) and lipogenesis through Ru-5-P-dependent inhibition of serine/threonine protein kinase LKB1 (show STK11 ELISA Kits)-AMPK (show PRKAA1 ELISA Kits) signalling.

  3. copy number gain of the PGD gene was consistently identified in cervical cancers but not in the normal tissues

  4. Results show that 6PGD activity is upregulated with increased lysine acetylation in primary leukemia cells from human patients, providing mechanistic insights into 6PGD upregulation in cancer cells.

  5. Expression of 6PGD positively correlates with advancing stage of lung carcinoma. Knockdown of 6PGD by shRNA potently inhibits c-Met tyrosine phosphorylation.

  6. Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence

  7. Data suggest that the affinity of Nox2 (show CYBB ELISA Kits) for NADPH (show NQO1 ELISA Kits) is increased in the presence of 6PGDH on cell stimulation.

  8. Hsa (show CD24 ELISA Kits)-miR (show MLXIP ELISA Kits)-132 and -212 were negatively correlated with PGD in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders.

Mouse (Murine) Phosphogluconate Dehydrogenase (PGD) interaction partners

  1. Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence

  2. Taken together, these data suggest that ADD1/SREBP1c (show SREBF1 ELISA Kits) is a key transcription factor for 6PGDH gene expression and would coordinate glucose metabolism and lipogenesis for energy homeostasis.

PGD Antigen Profile

Antigen Summary

6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies.

Gene names and symbols associated with PGD

  • phosphogluconate dehydrogenase (PGD) antibody
  • Phosphogluconate dehydrogenase (Pgd) antibody
  • phosphogluconate dehydrogenase (Pgd) antibody
  • phosphogluconate dehydrogenase L homeolog (pgd.L) antibody
  • phosphogluconate dehydrogenase (pgd) antibody
  • 6-phosphogluconate dehydrogenase, decarboxylating (GND1a|GND1b) antibody
  • 6-phosphogluconate dehydrogenase, decarboxylating (Thal_1580) antibody
  • 6-phosphogluconate dehydrogenase, decarboxylating (GY4MC1_3101) antibody
  • 6-phosphogluconate dehydrogenase, decarboxylating (Odosp_2189) antibody
  • 6-phosphogluconate dehydrogenase, decarboxylating (Marky_1024) antibody
  • 6-phosphogluconate dehydrogenase, decarboxylating (gnd) antibody
  • 6-phosphogluconate dehydrogenase, decarboxylating-like (LOC101451876) antibody
  • 6-pgd antibody
  • 6-PGDH antibody
  • 6Pgd antibody
  • 6pgdh antibody
  • 0610042A05Rik antibody
  • A7 antibody
  • AU019875 antibody
  • C78335 antibody
  • Cc2-27 antibody
  • CG3724 antibody
  • Dmel\\CG3724 antibody
  • EG:87B1.4 antibody
  • fi03d03 antibody
  • GND1b antibody
  • l(1)2Dc antibody
  • l(1)2De antibody
  • l(1)A7 antibody
  • l(1)G0385 antibody
  • l(1)N1 antibody
  • l(1)N3[90] antibody
  • l(1)Pgd antibody
  • l(1)Pgd-A antibody
  • l35 antibody
  • N1 antibody
  • Pdg antibody
  • Pgd antibody
  • wu:fi03d03 antibody
  • zgc:55585 antibody
  • zgc:111848 antibody

Protein level used designations for PGD

6-phosphogluconate dehydrogenase, decarboxylating , 6-phosphogluconate , 6-phosphogluconate dehydrogenase , CG3724-PA , CG3724-PB , NADP-6 phosphogluconate dehydrogenase , Pgd-PA , Pgd-PB , dehydrogenase , phosphogluconate dehydrogenase , 6-phosphogluconate dehydrogenase (decarboxylating) , 6-phosphogluconate dehydrogenase, decarboxylating-like

GENE ID SPECIES
5226 Homo sapiens
31185 Drosophila melanogaster
110208 Mus musculus
398848 Xenopus laevis
406762 Danio rerio
419450 Gallus gallus
443541 Ovis aries
514939 Bos taurus
5722476 Chlamydomonas reinhardtii
8815110 Thermocrinis albus DSM 14484
9929981 Geobacillus sp. Y4.1MC1
10253936 Odoribacter splanchnicus DSM 220712
10433922 Marinithermus hydrothermalis DSM 14884
10448388 Chlamydophila pecorum E58
100534626 Taeniopygia guttata
100598383 Nomascus leucogenys
397546 Sus scrofa
101451876 Ceratitis capitata
100360180 Rattus norvegicus
101788565 Cavia porcellus
101866917 Macaca fascicularis
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