anti-PTTG1 Antibodies

The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation.

Data Quality
  • 1
  • 24
Type
  • 69
    Primary
Target
  • 69
Reactivity
  • 68
  • 20
  • 16
  • 1
Application
  • 42
  • 32
  • 25
  • 16
  • 14
Host
  • 50
  • 18
  • 1
Clonality
  • 44
  • 25
Clone
  • 4
  • 3
  • 3
  • 1
  • 1
Binding Specificity
  • 5
  • 5
  • 3
  • 3
  • 3
Conjugate
  • 52
  • 3
  • 2
  • 2
  • 2
Isotype
  • 27
  • 6
  • 4
  • 3
  • 2
Format
  • 34
  • 3
Suggested next Filters
69 Products
ReactivityHuman
Application ELISA, FACS, IF, IHC
Order details Cat. No. ABIN6391382
$429.87
100 μg
Plus shipping costs $45.00
Delivery in 6 to 7 Business Days
ReactivityHuman
Application IHC, WB
Order details Cat. No. ABIN6146486
$393.25
Plus shipping costs $45.00
Delivery in 13 to 14 Business Days
ReactivityHuman
Application ICC, IHC, WB
Order details Cat. No. ABIN5014129
$245.00
100 μL
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
ReactivityHuman, Mouse
Application ELISA, ICC, IF, IHC, WB
Order details Cat. No. ABIN6258307
$390.77
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityMouse
Application ICC, IHC, WB
Order details Cat. No. ABIN5014128
$252.00
100 μL
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
ReactivityHuman, Mouse, Rat
Application ELISA, ICC, IF, IHC, WB
Order details Cat. No. ABIN6258306
$390.77
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application IF, WB
Order details Cat. No. ABIN948782
$440.00
50 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
Mouse, Monoclonal (DCS-280), IgG2a
ReactivityHuman, Mouse, Rat
Application IF, IHC (p), IP, WB
Order details Cat. No. ABIN487310
$467.50
0.1 mg
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman
Application IF, IHC (p), WB
Order details Cat. No. ABIN5534624
$550.00
400 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application IF/ICC, IHC, WB
Order details Cat. No. ABIN3003161
$640.17
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN3042643
$240.00
100 μg
Plus shipping costs $45.00
Delivery in 4 to 6 Business Days
ReactivityHuman, Mouse, Rat
Application IHC, ELISA, WB
Order details Cat. No. ABIN1849460
$323.60
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application IF, ELISA, WB
Order details Cat. No. ABIN1533575
$324.50
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman, Mouse, Rat
Application IHC, ELISA, WB
Order details Cat. No. ABIN1533781
$324.50
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application IF
Order details Cat. No. ABIN948781
$440.00
50 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
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PTTG1 Antigen Profile

Protein Summary

The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box (D box) that is required for its degradation by the APC. The acidic C-terminal region of the encoded protein can act as a transactivation domain. The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus.

Gene names and symbols associated with PTTG1

  • pituitary tumor-transforming 1 (PTTG1) antibody
  • pituitary tumor-transforming gene 1 (Pttg1) antibody
  • pituitary tumor-transforming 1 (Pttg1) antibody
  • securin, sister chromatid separation inhibitor (cut2) antibody
  • AW555095 antibody
  • C87862 antibody
  • EAP1 antibody
  • HPTTG antibody
  • Protein Cut2 antibody
  • Pttg antibody
  • PTTG1 antibody
  • Pttg3 antibody
  • Securin antibody
  • TUTR1 antibody

Protein level used designations for PTTG1

ESP1-associated protein 1 , pituitary tumor-transforming gene 1 protein , securin , tumor-transforming protein 1 , pituitary tumor-transforming protein 1 , pituitary tumor-transforming 1 , Pituitary tumor transforming , Pituitary tumor-transforming gene 1 protein , Cell untimely torn protein 2

GENE ID SPECIES
9232 Homo sapiens
397015 Sus scrofa
416158 Gallus gallus
479307 Canis lupus familiaris
508043 Bos taurus
696143 Macaca mulatta
30939 Mus musculus
64193 Rattus norvegicus
462238 Pan troglodytes
100848911 Bos taurus
2539641 Schizosaccharomyces pombe 972h-