PTTG1 ELISA Kits
The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation.
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PTTG1 ELISA Kit (Pituitary Tumor-Transforming 1) ELISA Kit
PTTG1 ELISA Kit (Pituitary Tumor-Transforming 1) ELISA Kit
PTTG1 Antigen Profile
Protein Summary
The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box (D box) that is required for its degradation by the APC. The acidic C-terminal region of the encoded protein can act as a transactivation domain. The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus.
Gene names and symbols associated with PTTG1
- pituitary tumor-transforming 1 (PTTG1) antibody
- pituitary tumor-transforming gene 1 (Pttg1) antibody
- pituitary tumor-transforming 1 (Pttg1) antibody
- securin, sister chromatid separation inhibitor (cut2) antibody
- AW555095 antibody
- C87862 antibody
- EAP1 antibody
- HPTTG antibody
- Protein Cut2 antibody
- Pttg antibody
- PTTG1 antibody
- Pttg3 antibody
- Securin antibody
- TUTR1 antibody
Protein level used designations for PTTG1
ESP1-associated protein 1 , pituitary tumor-transforming gene 1 protein , securin , tumor-transforming protein 1 , pituitary tumor-transforming protein 1 , pituitary tumor-transforming 1 , Pituitary tumor transforming , Pituitary tumor-transforming gene 1 protein , Cell untimely torn protein 2
| GENE ID | SPECIES |
|---|---|
| 9232 | Homo sapiens |
| 397015 | Sus scrofa |
| 416158 | Gallus gallus |
| 479307 | Canis lupus familiaris |
| 508043 | Bos taurus |
| 696143 | Macaca mulatta |
| 30939 | Mus musculus |
| 64193 | Rattus norvegicus |
| 462238 | Pan troglodytes |
| 100848911 | Bos taurus |
| 2539641 | Schizosaccharomyces pombe 972h- |
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