PTTG1 ELISA Kits

The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation.

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3 Products
Pre-coated, Samples: Serum, Plasma, Tissue Homogenate, Cell Lysate
ReactivityHuman
Detection MethodColorimetric, Sandwich ELISA
Detection Range31.2-2000 pg/mL
Order details Cat. No. ABIN821247
$910.56
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
Uncoated, Samples: Cell Culture Cells
ReactivityHuman
Detection MethodColorimetric, Cell ELISA
Detection RangeQualitative
Order details Cat. No. ABIN5648206
$380.00
96 tests
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
Uncoated, Samples: Cell Culture Cells
ReactivityHuman, Mouse, Rat
Detection MethodColorimetric, Cell ELISA
Detection RangeQualitative
Order details Cat. No. ABIN5648205
$380.00
96 tests
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
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PTTG1 Antigen Profile

Protein Summary

The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box (D box) that is required for its degradation by the APC. The acidic C-terminal region of the encoded protein can act as a transactivation domain. The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus.

Gene names and symbols associated with PTTG1

  • pituitary tumor-transforming 1 (PTTG1) antibody
  • pituitary tumor-transforming gene 1 (Pttg1) antibody
  • pituitary tumor-transforming 1 (Pttg1) antibody
  • securin, sister chromatid separation inhibitor (cut2) antibody
  • AW555095 antibody
  • C87862 antibody
  • EAP1 antibody
  • HPTTG antibody
  • Protein Cut2 antibody
  • Pttg antibody
  • PTTG1 antibody
  • Pttg3 antibody
  • Securin antibody
  • TUTR1 antibody

Protein level used designations for PTTG1

ESP1-associated protein 1 , pituitary tumor-transforming gene 1 protein , securin , tumor-transforming protein 1 , pituitary tumor-transforming protein 1 , pituitary tumor-transforming 1 , Pituitary tumor transforming , Pituitary tumor-transforming gene 1 protein , Cell untimely torn protein 2

GENE ID SPECIES
9232 Homo sapiens
397015 Sus scrofa
416158 Gallus gallus
479307 Canis lupus familiaris
508043 Bos taurus
696143 Macaca mulatta
30939 Mus musculus
64193 Rattus norvegicus
462238 Pan troglodytes
100848911 Bos taurus
2539641 Schizosaccharomyces pombe 972h-